Sepsis monitor

• US 7,941,199 B2
• Filed: 05/15/2007
• Issued: 05/10/2011
• Est. Priority Date: 05/15/2006
• Status: Active Grant

• Current Assignee: Masimo Corporation
• Original Assignee: Masimo Laboratories, Inc. (Masimo Corporation)
• Inventors: Kiani, Massi E.
• Primary Examiner(s): Layno; Carl H
• Assistant Examiner(s): SORIANO, BOBBY GILES
• Application Number:
  US11/803,936
• Publication Number:
  US 20080091088A1
• Time in Patent Office: 1,456 Days
• Field of Search: None
• US Class Current: 600/324
• CPC Class Codes: A61B 2560/0276 Determining malfunction
• CPC Class Codes: A61B 5/0205 Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
• CPC Class Codes: A61B 5/022 by applying pressure to close blood vessels, e.g. against the skin; Ophthalmodynamometers
• CPC Class Codes: A61B 5/02455 provided with high/low alarm devices
• CPC Class Codes: A61B 5/08 Detecting, measuring or recording devices for evaluating the respiratory organs A61B5/0205 takes precedence
• CPC Class Codes: A61B 5/082 Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath A61B5/083, A61B5/091 take precedence
• CPC Class Codes: A61B 5/14551 for measuring blood gases
• CPC Class Codes: A61B 5/412 Detecting or monitoring sepsis
• CPC Class Codes: A61B 5/6826 Finger
• CPC Class Codes: A61B 5/6838 Clamps or clips
• CPC Class Codes: A61B 7/04 Electric stethoscopes microphones, acoustic transducers therefor H04R
• CPC Class Codes: A61M 5/1723 using feedback of body parameters, e.g. blood-sugar, pressure measurement of body parameters A61B5/00

Abstract

Sensors are attached to a living being so as to generate corresponding sensor signals. A monitor is in communications with the sensors so as to derive physiological parameters responsive to the sensor signals. Predetermined limits are applied to the physiological parameters. At least one indicator responsive to the physiological parameters and the predetermined limits signal the onset of a sepsis condition in the living being.

Claims

1. A sepsis monitor comprising:

a plurality of sensors adapted to be attached to a living being so as to generate a corresponding plurality of sensor signals, at least one of said sensors comprising an optical sensor outputting a first signal of said at least one of said plurality of sensor signals, said first signal indicative of a blood parameter including at least one of oxygen saturation, methemoglobin, or carboxyhemoglobin;

a monitor in communication with the sensors so as to derive a plurality of physiological parameters responsive to the sensor signals, said parameters including at least one of methemoglobin or carboxyhemoglobin responsive to said first signal, and to apply a plurality of predetermined limits to the physiological parameters associated with sepsis; and

at least one indicator responsive to the monitor'"'"'s application of the predetermined limits to signal the onset of a sepsis condition in the living being.

2. The sepsis monitor according to claim 1 further comprising:

a treatment device adapted to be attached to the patient; and

a control in communication with the treatment device, wherein the control is responsive to the monitor so as to moderate treatment provided by the treatment device to the living being according to the sepsis condition.

3. The sepsis monitor according to claim 1 wherein the physiological parameters include at least two of respiration rate, pulse rate and temperature of the living being.

4. The sepsis monitor according to claim 1 wherein the physiological parameters include at least another of HbCO, HbMet, and blood pressure.

5. The sepsis monitor according to claim 2 wherein the treatment device is a drug administration device adapted to be intravenously connected to the living being so as to administer at least one drug to the patient in response to the control.

6. A method of electronically monitoring signals indicative of a patient condition to determine when to warn a caregiver that said patient condition is indicative of sepsis, the method comprising:

outputting a first signal from a noninvasive optical sensor indicative of an absorption of light by body tissue of said patient, said first signal also indicative of one or more physiological parameters of said patient;

outputting a second signal from one of (i) a noninvasive acoustic sensor applied to an area of skin around a patient'"'"'s throat where said second signal is indicative of acoustically sensed tracheal sounds or (ii) a noninvasive blood pressure cuff device where said second signal is indicative of blood pressure;

electronically processing with a processor said first signal to output measurement values for said one or more physiological parameters including at least one of methemoglobin or carboxyhemoglobin and processing with said processor said second signal to output measurement values for said one of said respiration or said blood pressure;

electronically applying with said processor a plurality of predetermined rules associated with sepsis to said measurement values; and

when said application of said rules indicates said patient condition is indicative of sepsis, outputting at least one of an audio or visual indication to said caregiver that a potential for sepsis exists.

7. The method according to claim 6, wherein the outputting includes activating a first colored light to indicate nonexistence of said potential for said sepsis and a second colored light to indicate said potential of said sepsis.

8. The method according to claim 6, further comprising sending a control signal to a drug administration device intravenously in communications with said patient, said control signal responsive to said indication of said sepsis, said device providing treatment for said sepsis.