Method for determining fluctuation in attentional state and overall attentional state
First Claim
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1. A method for diagnosing a psychological, neurological, or behavioral disorder in a subject, said method comprising:
- (a) providing from said subject scoring data that has been collected by (i) presenting to said subject a sequence comprising target and nontarget stimuli during a continuous testing period; and
(ii) scoring the response of said subject on the number of targets responded to and the number of nontargets responded to;
(b) on the basis of said scoring data, (i) dividing said sequence into three or more epochs and classifying the attentional state of said subject during each epoch, (ii) calculating the number of shifts in the attentional state of said subject during said continuous testing period, (iii) identifying epochs in which said subject is in an impulsive attentional state, and (iv) calculating the amount of time said subject is in an impulsive attentional state during said continuous testing period; and
(c) on the basis of the results of step (b), diagnosing said subject.
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Abstract
The invention provides methods for determining shifts in the attentional state of a subject. These methods are useful for diagnosing subjects with a psychological or behavioral disorder. The invention also features methods for determining the effect of a therapy on the overall attentional state and shifts in the attentional state of a subject.
31 Citations
100 Claims
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1. A method for diagnosing a psychological, neurological, or behavioral disorder in a subject, said method comprising:
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(a) providing from said subject scoring data that has been collected by (i) presenting to said subject a sequence comprising target and nontarget stimuli during a continuous testing period; and
(ii) scoring the response of said subject on the number of targets responded to and the number of nontargets responded to;(b) on the basis of said scoring data, (i) dividing said sequence into three or more epochs and classifying the attentional state of said subject during each epoch, (ii) calculating the number of shifts in the attentional state of said subject during said continuous testing period, (iii) identifying epochs in which said subject is in an impulsive attentional state, and (iv) calculating the amount of time said subject is in an impulsive attentional state during said continuous testing period; and (c) on the basis of the results of step (b), diagnosing said subject. - View Dependent Claims (3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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2. A method for diagnosing a psychological, neurological, or behavioral disorder in a subject, said method comprising:
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(a) presenting to said subject a sequence comprising target and nontarget stimuli during a continuous testing period, recording the responses of said subject to produce subject data, and transmitting said subject data to a computer for analysis; (b) receiving the results of said analysis, wherein said analysis comprises (i) scoring the response of said subject on the number of targets responded to and the number of nontargets responded to; and
(ii) on the basis of said scoring data, (b1) dividing said sequence into three or more epochs and classifying the attentional state of said subject during each epoch, (b2) calculating the number of shifts in the attentional state of said subject during said continuous testing period, (b3) identifying epochs in which said subject is in an impulsive attentional state, and (b4) calculating the amount of time said subject is in an impulsive attentional state during said continuous testing period; and(c) on the basis of the analysis of step (b), diagnosing said subject.
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13. A method for diagnosing a psychological, neurological, or behavioral disorder in a subject, said method comprising:
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(a) providing from said subject scoring data that has been collected by (i) presenting to said subject a sequence comprising target and nontarget stimuli during a continuous testing period; and
(ii) scoring the response of said subject on the number of targets responded to and the number of nontargets responded to;(b) on the basis of said scoring data, (i) dividing said sequence into three or more epochs and classifying the attentional state of said subject during each epoch, (ii) calculating the number of shifts in the attentional state of said subject during said continuous testing period, (iii) identifying epochs in which said subject is in a distracted attentional state, and (iv) calculating the amount of time said subject is in a distracted attentional state during said continuous testing period; and (c) on the basis of the results of step (b), diagnosing said subject. - View Dependent Claims (15, 16, 17, 18, 19, 20, 21, 22, 23, 24)
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14. A method for diagnosing a psychological, neurological, or behavioral disorder in a subject, said method comprising:
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(a) presenting to said subject a sequence comprising target and nontarget stimuli during a continuous testing period, recording the responses of said subject to produce subject data, and transmitting said subject data to a computer for analysis; (b) receiving the results of said analysis, wherein said analysis comprises (i) scoring the response of said subject on the number of targets responded to and the number of nontargets responded to; and
(ii) on the basis of said scoring data, (b1) dividing said sequence into three or more epochs and classifying the attentional state of said subject during each epoch, (b2) calculating the number of shifts in the attentional state of said subject during said continuous testing period, (b3) identifying epochs in which said subject is in a distracted attentional state, and (b4) calculating the amount of time said subject is in a distracted attentional state during said continuous testing period; and(c) on the basis of the analysis of step (b), diagnosing said subject.
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25. A method for diagnosing a psychological, neurological, or behavioral disorder in a subject, said method comprising:
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(a) providing from said subject scoring data that has been collected by (i) presenting to said subject a sequence comprising target and nontarget stimuli during a continuous testing period; and
(ii) scoring the response of said subject on the number of targets responded to and the number of nontargets responded to;(b) on the basis of said scoring data, (i) dividing said sequence into three or more epochs and classifying the attentional state of said subject during each epoch, (ii) calculating the number of shifts in the attentional state of said subject during said continuous testing period, (iii) identifying epochs in which said subject is in an on-task attentional state, and (iv) calculating the amount of time said subject is in an on-task attentional state during said continuous testing period; and (c) on the basis of the results of step (b), diagnosing said subject. - View Dependent Claims (27, 28, 29, 30, 31, 32, 33, 34, 35, 36)
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26. A method for diagnosing a psychological, neurological, or behavioral disorder in a subject, said method comprising:
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(a) presenting to said subject a sequence comprising target and nontarget stimuli during a continuous testing period, recording the responses of said subject to produce subject data, and transmitting said subject data to a computer for analysis; (b) receiving the results of said analysis, wherein said analysis comprises (i) scoring the response of said subject on the number of targets responded to and the number of nontargets responded to; and
(ii) on the basis of said scoring data, (b1) dividing said sequence into three or more epochs and classifying the attentional state of said subject during each epoch, (b2) calculating the number of shifts in the attentional state of said subject during said continuous testing period, (b3) identifying epochs in which said subject is in an on-task attentional state, and (b4) calculating the amount of time said subject is in an on-task attentional state during said continuous testing period; and(c) on the basis of the analysis of step (b), diagnosing said subject.
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37. A method for diagnosing a psychological, neurological, or behavioral disorder in a subject, said method comprising:
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(a) providing from said subject scoring data that has been collected by (i) presenting to said subject a sequence comprising target and nontarget stimuli during a continuous testing period; and
(ii) scoring the response of said subject on the number of targets responded to and the number of nontargets responded to;(b) on the basis of said scoring data, (i) dividing said sequence into three or more epochs and classifying the attentional state of said subject during each epoch, (ii) calculating the number of shifts in the attentional state of said subject during said continuous testing period, (iii) identifying epochs in which said subject is in a randomly responding attentional state, and (iv) calculating the amount of time said subject is in a randomly responding attentional state during said continuous testing period; and (c) on the basis of the results of step (b), diagnosing said subject. - View Dependent Claims (39, 40, 41, 42, 43, 44, 45, 46, 47, 48)
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38. A method for diagnosing a psychological, neurological, or behavioral disorder in a subject, said method comprising:
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(a) presenting to said subject a sequence comprising target and nontarget stimuli during a continuous testing period, recording the responses of said subject to produce subject data, and transmitting said subject data to a computer for analysis; (b) receiving the results of said analysis, wherein said analysis comprises (i) scoring the response of said subject on the number of targets responded to and the number of nontargets responded to; and
(ii) on the basis of said scoring data, (b1) dividing said sequence into three or more epochs and classifying the attentional state of said subject during each epoch, (b2) calculating the number of shifts in the attentional state of said subject during said continuous testing period, (b3) identifying epochs in which said subject is in a randomly responding attentional state, and (b4) calculating the amount of time said subject is in a randomly responding attentional state during said continuous testing period; and(c) on the basis of the analysis of step (b), diagnosing said subject.
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49. A method for determining the efficacy of a therapy for a subject, said method comprising:
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(a) providing from said subject scoring data that has been collected by (i) presenting to said subject a sequence comprising target and nontarget stimuli during a continuous testing period; and
(ii) scoring the response of said subject on the number of targets responded to and the number of nontargets responded to;(b) on the basis of said scoring data, (i) dividing said sequence into three or more epochs and classifying the attentional state of said subject during each epoch, (ii) calculating the number of shifts in the attentional state of said subject during said continuous testing period, (iii) identifying epochs in which said subject is in an impulsive attentional state, and (iv) calculating the amount of time said subject is in an impulsive attentional state during said continuous testing period; (c) providing control data produced by performing steps (a) and (b) on either said subject when not undergoing treatment with said therapy or on a control subject not undergoing treatment with said therapy; and (d) comparing the results of steps (b) to the control data of step (c) to determine the effect of said therapy on said subject. - View Dependent Claims (51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61)
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50. A method for determining the efficacy of a therapy for a subject, said method comprising:
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(a) presenting to said subject a sequence comprising target and nontarget stimuli during a continuous testing period, recording the responses of said subject to produce subject data, and transmitting said subject data to a computer for analysis; (b) receiving the results of said analysis, wherein said analysis comprises (i) scoring the response of said subject on the number of targets responded to and the number of nontargets responded to; and
(ii) on the basis of said scoring data, (b1) dividing said sequence into three or more epochs and classifying the attentional state of said subject during each epoch, (b2) calculating the number of shifts in the attentional state of said subject during said continuous testing period, (b3) identifying epochs in which said subject is in an impulsive attentional state, and (b4) calculating the amount of time said subject is in an impulsive attentional state during said continuous testing period;(c) providing control data produced by performing steps (a) and (b) on either said subject when not undergoing treatment with said therapy or on a control subject not undergoing treatment with said therapy; and (d) on the basis of a comparison of the results of step (b) to the control data of step (c), determining the effect of said therapy on said subject.
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62. A method for determining the efficacy of a therapy for a subject, said method comprising:
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(a) providing from said subject scoring data that has been collected by (i) presenting to said subject a sequence comprising target and nontarget stimuli during a continuous testing period; and
(ii) scoring the response of said subject on the number of targets responded to and the number of nontargets responded to;(b) on the basis of said scoring data, (i) dividing said sequence into three or more epochs and classifying the attentional state of said subject during each epoch, (ii) calculating the number of shifts in the attentional state of said subject during said continuous testing period, (iii) identifying epochs in which said subject is in a distracted attentional state, and (iv) calculating the amount of time said subject is in a distracted attentional state during said continuous testing period; (c) providing control data produced by performing steps (a) and (b) on either said subject when not undergoing treatment with said therapy or on a control subject not undergoing treatment with said therapy; and (d) comparing the results of steps (b) to the control data of step (c) to determine the effect of said therapy on said subject. - View Dependent Claims (64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74)
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63. A method for determining the efficacy of a therapy for a subject, said method comprising:
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(a) presenting to said subject a sequence comprising target and nontarget stimuli during a continuous testing period, recording the responses of said subject to produce subject data, and transmitting said subject data to a computer for analysis; (b) receiving the results of said analysis, wherein said analysis comprises (i) scoring the response of said subject on the number of targets responded to and the number of nontargets responded to; and
(ii) on the basis of said scoring data, (b1) dividing said sequence into three or more epochs and classifying the attentional state of said subject during each epoch, (b2) calculating the number of shifts in the attentional state of said subject during said continuous testing period, (b3) identifying epochs in which said subject is in a distracted attentional state, and (b4) calculating the amount of time said subject is in a distracted attentional state during said continuous testing period;(c) providing control data produced by performing steps (a) and (b) on either said subject when not undergoing treatment with said therapy or on a control subject not undergoing treatment with said therapy; and (d) on the basis of a comparison of the results of step (b) to the control data of step (c), determining the effect of said therapy on said subject.
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75. A method for determining the efficacy of a therapy for a subject, said method comprising:
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(a) providing from said subject scoring data that has been collected by (i) presenting to said subject a sequence comprising target and nontarget stimuli during a continuous testing period; and
(ii) scoring the response of said subject on the number of targets responded to and the number of nontargets responded to;(b) on the basis of said scoring data, (i) dividing said sequence into three or more epochs and classifying the attentional state of said subject during each epoch, (ii) calculating the number of shifts in the attentional state of said subject during said continuous testing period, (iii) identifying epochs in which said subject is in an on-task attentional state, and (iv) calculating the amount of time said subject is in an on-task attentional state during said continuous testing period; (c) providing control data produced by performing steps (a) and (b) on either said subject when not undergoing treatment with said therapy or on a control subject not undergoing treatment with said therapy; and (d) comparing the results of steps (b) to the control data of step (c) to determine the effect of said therapy on said subject. - View Dependent Claims (77, 78, 79, 80, 81, 82, 83, 84, 85, 86, 87)
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76. A method for determining the efficacy of a therapy for a subject, said method comprising:
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(a) presenting to said subject a sequence comprising target and nontarget stimuli during a continuous testing period, recording the responses of said subject to produce subject data, and transmitting said subject data to a computer for analysis; (b) receiving the results of said analysis, wherein said analysis comprises (i) scoring the response of said subject on the number of targets responded to and the number of nontargets responded to; and
(ii) on the basis of said scoring data, (b1) dividing said sequence into three or more epochs and classifying the attentional state of said subject during each epoch, (b2) calculating the number of shifts in the attentional state of said subject during said continuous testing period, (b3) identifying epochs in which said subject is in an on-task attentional state, and (b4) calculating the amount of time said subject is in an on-task attentional state during said continuous testing period;(c) providing control data produced by performing steps (a) and (b) on either said subject when not undergoing treatment with said therapy or on a control subject not undergoing treatment with said therapy; and (d) on the basis of a comparison of the results of step (b) to the control data of step (c), determining the effect of said therapy on said subject.
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88. A method for determining the efficacy of a therapy for a subject, said method comprising:
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(a) providing from said subject scoring data that has been collected by (i) presenting to said subject a sequence comprising target and nontarget stimuli during a continuous testing period; and
(ii) scoring the response of said subject on the number of targets responded to and the number of nontargets responded to;(b) on the basis of said scoring data, (i) dividing said sequence into three or more epochs and classifying the attentional state of said subject during each epoch, (ii) calculating the number of shifts in the attentional state of said subject during said continuous testing period, (iii) identifying epochs in which said subject is in a randomly responding attentional state, and (iv) calculating the amount of time said subject is in a randomly responding attentional state during said continuous testing period; (c) providing control data produced by performing steps (a) and (b) on either said subject when not undergoing treatment with said therapy or on a control subject not undergoing treatment with said therapy; and (d) comparing the results of steps (b) to the control data of step (c) to determine the effect of said therapy on said subject. - View Dependent Claims (90, 91, 92, 93, 94, 95, 96, 97, 98, 99, 100)
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89. A method for determining the efficacy of a therapy for a subject, said method comprising:
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(a) presenting to said subject a sequence comprising target and nontarget stimuli during a continuous testing period, recording the responses of said subject to produce subject data, and transmitting said subject data to a computer for analysis; (b) receiving the results of said analysis, wherein said analysis comprises (i) scoring the response of said subject on the number of targets responded to and the number of nontargets responded to; and
(ii) on the basis of said scoring data, (b1) dividing said sequence into three or more epochs and classifying the attentional state of said subject during each epoch, (b2) calculating the number of shifts in the attentional state of said subject during said continuous testing period, (b3) identifying epochs in which said subject is in a randomly responding attentional state, and (b4) calculating the amount of time said subject is in a randomly responding attentional state during said continuous testing period;(c) providing control data produced by performing steps (a) and (b) on either said subject when not undergoing treatment with said therapy or on a control subject not undergoing treatment with said therapy; and (d) on the basis of a comparison of the results of step (b) to the control data of step (c), determining the effect of said therapy on said subject.
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Specification