Measuring method and measuring device

• US 7,942,831 B2
• Filed: 04/24/2007
• Issued: 05/17/2011
• Est. Priority Date: 04/28/2006
• Status: Expired due to Fees

• Current Assignee: Sysmex Corporation
• Original Assignee: Sysmex Corporation
• Inventors: Maekawa, Yasunori, Ohnishi, Yasuhito, Mishima, Katsutoshi, Sawa, Kenichi
• Primary Examiner(s): Hidenburg; Max
• Assistant Examiner(s): Foreman; Jonathan M
• Application Number:
  US11/789,373
• Publication Number:
  US 20080021290A1
• Time in Patent Office: 1,484 Days
• Field of Search: 600/562, 600/573, 600/583, 600/584, 600/345
• US Class Current: 600/573
• CPC Class Codes: A61B 10/0045 Devices for taking samples of body liquids devices for taking blood samples A61B5/15
• CPC Class Codes: A61B 2010/008 Interstitial fluid
• CPC Class Codes: A61B 5/14514 using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/681 Wristwatch-type devices

Abstract

The present invention is to present a measuring device which can conduct stable extraction and measurement of interstitial fluid. The measuring device comprises: a device body which comprises an extraction part for extracting body fluid from a living body and a measuring part for measuring a biological component contained in the extracted body fluid; a holding member which holds the device body and has an opening part for defining a measurement area on the living body; and a mounting member for mounting the holding member on the living body; wherein the measurement area on the living body is defined by the opening part when the holding member is mounted on the living body by the mounting member.

Claims

1. A measuring device, comprising:

a device body which comprises an extraction part for extracting body fluid from a living body and a measuring part for measuring a biological component contained in the extracted body fluid;

a holding member which holds the device body and has an opening part for defining a measurement area on the living body; and

a mounting member for mounting the holding member on the living body;

wherein the measurement area on the living body is defined by the opening part when the holding member is mounted on the living body by the mounting member, and

wherein the mounting member comprises a tightening part which is configured to tighten the living body between the tightening part and the holding part, and a connecting part which connects the tightening part and the holding part so that a distance between the tightening part and the holding part is changeable.

2. The measuring device of claim 1,

wherein the opening part of the holding member is configured to receive a micropore forming device for forming a micropore on the living body to form a micropore in the measurement area via the opening part, and

wherein the extraction part is configured to extract the body fluid from the micropore formed by the micropore forming device.

3. The measuring device of claim 1, wherein

the extraction part is detachably attached to the device body.

4. The measuring device of claim 1,

wherein the device body is held by the holding member so that the measuring device has a first state and a second state, and

wherein, in the first state, the extraction part contacts the living body via the opening part, and in the second state, the extraction part is separated from the living body.

5. The measuring device of claim 4, wherein

the device body is held by the holding member so that the device body is movable relative to the holding member, and the measuring device changes between the first state and the second state by movements of the device body.

6. The measuring device of claim 1, wherein

the connecting part connects the tightening part to the holding part so that the tightening part is linearly movable relative to the holding part.

7. The measuring device of claim 1, wherein

one end of the holding part and one end of the tightening part are connected by the connecting part, and the other end of the holding part and the other end of the tightening part are separated from each other.

8. The measuring device of claim 1, wherein

the measurement area is defined by the opening part when the living body is held between the tightening part and the holding member.

9. The measuring device of claim 1, wherein

the tightening part is flexible so as to become in close contact with the living body while the living body is held between the tightening part and the holding member.

10. The measuring device of claim 1, wherein

a surface of the tightening part, which is facing the holding member, is formed concavely.

11. The measuring device of claim 1, wherein

a surface of the holding member, which is facing the tightening part, is formed concavely.

12. The measuring device of claim 1,

wherein the connecting part comprises a first part, and the holding member comprises a second part, and

wherein the first part and the second part form a ratchet mechanism which regulates a moving direction of the tightening part relative to the holding member.

13. The measuring device of claim 12, wherein

the ratchet mechanism allows the tightening part to move toward the holding member and restricts the tightening part from moving in a separating direction from the holding member.

14. The measuring device of claim 13, wherein

the second part of the holding member comprises a release mechanism which releases the tightening part from restriction by the ratchet mechanism on moving in the separating direction.

15. The measuring device of claim 1, further comprising

a power source for supplying a voltage,

wherein the extraction part comprises a first electrode connected to one pole of the power source, and at least one of the holding member and the mounting member is used as a second electrode connected to the other pole of the power source so that the power source supplies a voltage to the living body through the first electrode and the second electrode.

16. The measuring device of claim 1, wherein

a contact surface of at least one of the holding member and the mounting member, which contacts the living body, is formed of an electrically conductive material.

17. A measuring device, comprising:

a device body which comprises an extraction part for extracting body fluid from a living body and a measuring part for measuring a biological component contained in the extracted body fluid;

an area defining member which has an opening part for defining a measurement area on the living body and to which the device body is detachably attached; and

a mounting member for mounting the area defining member on the living body;

wherein the measurement area on the living body is defined by the opening part when the area defining member is mounted on the living body by the mounting member, and

the mounting member comprises a tightening part which is configured to tighten the living body between the tightening part and the holding part, and a connecting part which connects the tightening part and the area defining member so that a distance between the tightening part and the area defining member is changeable.