Treating valve failure

• US 7,942,927 B2
• Filed: 03/09/2005
• Issued: 05/17/2011
• Est. Priority Date: 03/15/2004
• Status: Expired due to Fees

• Current Assignee: Clif Alferness, David Kaye, John Power
• Original Assignee: Baker Medical Research Institute
• Inventors: Bilney, Adam Lucas, Alferness, Clifton A., Power, John Melmouth, Kaye, David Martin
• Primary Examiner(s): Ho; (Jackie) Tan-Uyen T
• Assistant Examiner(s): Dang; Son
• Application Number:
  US10/592,839
• Publication Number:
  US 20080071364A1
• Time in Patent Office: 2,260 Days
• Field of Search: 623/2.11, 623/2.36, 623/2.38, 623/2.39, 623/2.4, 623/1.36, 606/153
• US Class Current: 623/2.11
• CPC Class Codes: A61F 2/2445 Annuloplasty rings in direct contact with the valve annulus

Abstract

A device (1) for treating valve failure in a patient is provided. The device has one or more engaging zones (3) for engaging the device with the annulus of the valve being treated. The device also has pre-disposition means for changing the geometry of the device to a predetermined configuration which is suitable for constricting the valve annulus. The device is compressible for percutaneous delivery to the valve. When in the predetermined configuration, the engaged device constricts the valve annulus facilitating substantial closure of leaflets of the valve.

Claims

1. A device for treating valve failure in a patient, the device having:

(a) one or more engaging zones for engaging the device with a valve annulus of the valve being treated;

(b) pre-disposition means for changing the geometry of the device to a predetermined configuration suitable for constricting the valve annulus; and

(c) releasably engageable expansion means including one or more struts configured to expand the periphery of the device to substantially match the internal diameter geometry of the valve annulus

wherein the device is compressible within a delivery lumen for percutaneous delivery to the valve, and wherein the one or more struts facilitate expansion of the device when released from the delivery lumen to facilitate engagement of one or more engaging zones of the device with the untreated valve annulus, and wherein upon release of the one or more struts the device assumes the predetermined configuration and constricts the valve annulus facilitating substantial closure of leaflets of the valve.

2. A device for treating valve failure according to claim 1 wherein the device when released from the delivery lumen, is expandable to substantially match the geometry of the untreated valve annulus to facilitate engagement of the one or more engaging zones with the valve annulus, and capable of returning to the predetermined configuration.

3. A device for treating valve failure according to claim 1 wherein the device is made from a biocompatible material and the pre-disposition means includes a shape memory inherent in the material, said shape memory corresponding to the predetermined configuration.

4. A device for treating valve failure according to claim 3 wherein the biocompatible material includes a metal alloy.

5. A device for treating valve failure according to claim 4 wherein the alloy includes nickel and titanium.

6. A device for treating valve failure according to claim 1 wherein one or more of the engaging zones includes a tooth for engaging the valve annulus.

7. A device for treating valve failure according to claim 1 wherein one or more of the engaging zones includes a barb.

8. A device for treating valve failure according to claim 1 wherein the device is substantially annular and torsionally compressible for percutaneous delivery to the valve by coiling the device upon itself within the delivery lumen.

9. A device for treating valve failure according to claim 1 wherein the device is substantially annular and radially compressible within the delivery lumen for percutaneous delivery to the valve.

10. A device for treating valve failure according to claim 1 wherein the device is a nitinol coil and the engaging zones include laser-cut teeth formed in a surface of the device, said surface being configured to engage with the valve annulus.

11. A device for treating valve failure according to claim 1 wherein the valve being treated is a valve of the heart.

12. A device for treating valve failure according to claim 1 wherein the heart valve is the tricuspid valve.

15. A device for treating valve failure according to claim 1 wherein the device comprises Nitinol tubing having engaging zones in the form of teeth, and having helical shape when compressed within the delivery lumen for percutaneous delivery to the valve, wherein when released from the delivery lumen, the teeth rotate outward to engage the valve annulus.

16. A device for treating valve failure according to claim 1 further including retaining means selected from the group comprising a hook, anchor or screw for engaging tissue in the vicinity of the valve and adapted to maintain the position of the repair device when attached to the valve annulus.

17. A device for treating valve failure according to claim 1, the device having annular shape and compressible for percutaneous delivery by inwardly collapsing the device to fit within the delivery lumen.

13. Apparatus for deploying a valve repair device in a patient, the apparatus including:

(a) positioning means to position the repair device relative to the valve;

(b) coupling means for releasably coupling the repair device to the positioning means; and

(c) releasably engageable expansion means including one or more struts configured to expand the periphery of the repair device to substantially match the internal diameter geometry of the untreated valve annulus;

wherein the repair device comprises a pre-disposition means for changing the geometry of the device to a predetermined configuration suitable for constricting the valve annulus, and

wherein the positioning means and the coupling means are configured to deliver the repair device to a region of the valve within a percutaneous delivery lumen and wherein after delivery of the valve repair device from the delivery lumen the releasably engageable expansion means facilitates engagement of one or more engaging zones of the repair device with the valve annulus.

14. Apparatus for deploying a valve repair device according to claim 13 in combination with a valve repair device that is coupled by said coupling means to said positioning means where the device comprises one or more engaging zones for engaging the device with a valve annulus of the valve being treated.

18. The combination of claim 14, wherein the apparatus is adapted to deploy the valve repair device from a delivery lumen by rotating the device in a first direction and is adapted to engage the engaging zones of the deployed device with the annular tissue by rotating the device in a second direction.