Ultrasound within MRI scanners for guidance of MRI pulse sequences

• US 7,945,304 B2
• Filed: 11/20/2001
• Issued: 05/17/2011
• Est. Priority Date: 11/20/2001
• Status: Active Grant

• Current Assignee: David A. Feinberg
• Original Assignee: David A. Feinberg
• Inventors: Feinberg, David A.
• Primary Examiner(s): Casler; Brian
• Assistant Examiner(s): CWERN, JONATHAN
• Application Number:
  US10/472,838
• Publication Number:
  US 20040267111A1
• Time in Patent Office: 3,465 Days
• Field of Search: 324/307, 324/309, 600/411, 600/413, 600/427, 600/437, 600/439
• US Class Current: 600/411
• CPC Class Codes: A61B 5/0035 adapted for acquisition of images from more than one imaging mode, e.g. combining MRI and optical tomography
• CPC Class Codes: A61B 5/7285 for synchronising or triggering a physiological measurement or image acquisition with a physiological event or waveform, e.g. an ECG signal A61B6/5205, A61B6/541, A61B8/5207, A61B8/543 take precedence
• CPC Class Codes: A61B 5/7289 Retrospective gating, i.e. associating measured signals or images with a physiological event after the actual measurement or image acquisition, e.g. by simultaneously recording an additional physiological signal during the measurement or image acquisition
• CPC Class Codes: A61B 5/7292 Prospective gating, i.e. predicting the occurrence of a physiological event for use as a synchronisation signal
• CPC Class Codes: A61B 8/08 Detecting organic movements or changes, e.g. tumours, cysts, swellings A61B8/02 - A61B8/06 take precedence
• CPC Class Codes: A61B 8/0883 for diagnosis of the heart
• CPC Class Codes: A61B 8/4245 involving determining the position of the probe, e.g. with respect to an external reference frame or to the patient
• CPC Class Codes: A61B 8/4416 related to combined acquisition of different diagnostic modalities, e.g. combination of ultrasound and X-ray acquisitions
• CPC Class Codes: A61B 8/4477 using several separate ultrasound transducers or probes
• CPC Class Codes: A61B 8/488 involving Doppler signals
• CPC Class Codes: A61B 8/543 involving acquisition triggered by a physiological signal

Abstract

A process and system acquiring both ultrasound and MRI data from a patient in an MRI scanner and using one to automatically guide or improve the other. The ultrasound data can track the motion of an organ such as a cardiac artery or the diaphragm and the resulting motion information can automatically guide MRI data acquisition to keep the imaging volume at the organ or interest, or can be used to accept or reject MRI data in the process of forming an MRI image, based on whether the organ of interest was within an acceptable range of positions. Conversely, the MRI unit can guide the ultrasound data acquisition so it is properly timed or otherwise controlled in accordance with MRI data acquisition.

Claims

1. A process of acquiring ultrasound data and magnetic resonance imaging (MRI) data of a patient in an MRI scanner such that a magnetic resonance (MR) imaging volume moves relative to the MRI scanner, under guidance from said ultrasound data, to track movement of an organ of the patient that moves relative to the MRI scanner to a plurality of different positions relative to the MRI scanner, comprising:

acquiring ultrasound data indicative of a changing position of a body organ of the patient while the organ is moving relative to the MRI scanner;

acquiring MRI data from an MR imaging volume in the patient substantially concurrently with the acquisition of the ultrasound data;

computer-processing the ultrasound data to generate guidance information causing said MR imaging volume to move relative to the MRI scanner to track the changing position of said body organ such that the MR imaging volume and said moving organ undergo matching movement with respect to the MRI scanner during said MRI data acquisition;

and

computer-processing the MRI data to generate images of at least said body organ with inherent correction for motion artifacts due to said movement of the organ relative to the MRI scanner.

2. A process as in claim 1 in which said acquiring of ultrasound data comprises using at least one ultrasound transducer acoustically coupled with the patient.

3. A process as in claim 2 in which said acquiring of ultrasound data comprises using a plurality of ultrasound transducer assemblies spaced from each other along the patient and acoustically coupled to the patient to transmit ultrasound energy along beam paths at an angle to each other.

4. A process as in claim 2 in which the acquiring of ultrasound data comprises forming ultrasound images of patient anatomy.

5. A process as in claim 4 in which said forming of ultrasound images comprises forming said ultrasound images at a rate exceeding 10 images per second.

6. A process as in claim 4 including using edge detection processing to identify and track motion in space of said moving patient organ at times related to said acquiring said MRI data.

7. A process as in claim 4 in which said acquiring of said MRI data includes forming an MR image.

8. A process as in claim 7 including selectively displaying said ultrasound and MR images.

9. A process as in claim 8 including displaying a fused image related to a combination of said ultrasound and MR images.

10. A process as in claim 4 comprising using said ultrasound data to alter, during said acquisition of said MRI data, at least one of a magnetic gradient amplitude, a magnetic gradient phase, and a radio frequency pulse used in said acquisition of said MRI data.