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Detecting incomplete fill of biosensors

  • US 7,945,394 B2
  • Filed: 06/16/2005
  • Issued: 05/17/2011
  • Est. Priority Date: 06/17/2004
  • Status: Active Grant
First Claim
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1. A method of detecting an incomplete filling of a liquid sample in an electrochemical biosensor having working and counter electrodes, the method comprising the acts of:

  • (a) applying a constant electrical potential across said working and counter electrodes for a predetermined period of time;

    (b) measuring the current passing between said working and counter electrodes;

    (c) collecting values of the current measured in act (b) at predetermined times during said predetermined period of time of act (a);

    (d) determining by linear regression the slope of a line defined by the values of current collected in act (c); and

    (e) reporting as incompletely filled a biosensor exhibiting a positive slope of a line as determined in act (d).

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