Devices, systems, methods and tools for continuous glucose monitoring
First Claim
1. A method of in vivo monitoring of an individual'"'"'s interstitial fluid comprising:
- creating a plurality of fluid paths through a stratum corneum area of the individual'"'"'s skin, the fluid paths each comprising a distal end in fluid communication with interstitial fluid of the individual, a proximal end in analyte communication with a sensing area located outside of the patient'"'"'s body, and an interior space extending between the distal and proximal ends of the fluid path;
moving sensing fluid out of a sensing fluid reservoir and into the sensing area;
holding the sensing fluid in the sensing area in a non-flowing manner;
allowing at least one analyte to passively diffuse from the patient'"'"'s interstitial fluid through the fluid paths and into the sensing area;
sensing a concentration of the at least one analyte in the sensing fluid using a sensor located at least partially in the sensing area during the holding step.
4 Assignments
0 Petitions
Accused Products
Abstract
One aspect of the invention provides a glucose monitor having a plurality of tissue piercing elements, each tissue piercing element having a distal opening, a proximal opening and interior space extending between the distal and proximal openings; a sensing area in fluid communication with the proximal openings of the tissue piercing elements; sensing fluid extending from the sensing area into substantially the entire interior space of the tissue piercing elements; and a glucose sensor adapted to detect a concentration of glucose in the sensing fluid within the sensing area. Another aspect of the invention provides a method of in vivo monitoring of an individual'"'"'s interstitial fluid glucose concentration including the following steps: inserting distal ends of a plurality of tissue piercing elements through a stratum corneum area of the individual'"'"'s skin, the tissue piercing elements each having a distal opening, a proximal opening, an interior space extending between the distal and proximal openings, and a sensing fluid filling substantially the entire interior space; and sensing a glucose concentration of the sensing fluid.
-
Citations
16 Claims
-
1. A method of in vivo monitoring of an individual'"'"'s interstitial fluid comprising:
creating a plurality of fluid paths through a stratum corneum area of the individual'"'"'s skin, the fluid paths each comprising a distal end in fluid communication with interstitial fluid of the individual, a proximal end in analyte communication with a sensing area located outside of the patient'"'"'s body, and an interior space extending between the distal and proximal ends of the fluid path; moving sensing fluid out of a sensing fluid reservoir and into the sensing area; holding the sensing fluid in the sensing area in a non-flowing manner; allowing at least one analyte to passively diffuse from the patient'"'"'s interstitial fluid through the fluid paths and into the sensing area; sensing a concentration of the at least one analyte in the sensing fluid using a sensor located at least partially in the sensing area during the holding step. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16)
Specification