Using implanted sensors for feedback control of implanted medical devices

• US 7,949,394 B2
• Filed: 05/12/2010
• Issued: 05/24/2011
• Est. Priority Date: 09/09/2005
• Status: Expired due to Fees

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Chavan, Abhijeet V., Salo, Rodney W.
• Primary Examiner(s): Layno; Carl H.
• Assistant Examiner(s): MORALES, JON ERIC C
• Application Number:
  US12/778,779
• Publication Number:
  US 20100222833A1
• Time in Patent Office: 377 Days
• Field of Search: 607/44, 607/23, 607/17, 607/3
• US Class Current: 607/17
• CPC Class Codes: A61N 1/3621 for treating or preventing abnormally high heart rate
• CPC Class Codes: A61N 1/36564 controlled by blood pressure
• CPC Class Codes: A61N 1/3925 Monitoring; Protecting

Abstract

A system and method for administering a therapeutic treatment to the heart includes a pressure sensor positioned in the pulmonary artery, an implantable medical device located remotely from the sensor, and communication means for communicating pressure data from the pressure sensor to the implantable medical device. The system includes a control module operatively coupled to the implantable medical device. The control module is adapted for comparing the pulmonary arterial pressure data to a pre-programmed value, adjusting an operating parameter of the implantable medical device based on the relationship of the pulmonary arterial pressure to the pre-programmed value, and repeating this process until the relationship between the pulmonary arterial pressure data and the pre-programmed value is such that no adjustment is necessary.

Claims

1. A system for administering a therapeutic treatment, the system comprising:

a pressure sensor adapted for positioning in the pulmonary artery and collecting data representative of at least one of systolic pressure, diastolic pressure, pulse pressure, heart rate or pre-ejection period based on pressure in the pulmonary artery;

an implantable medical device including a lead located remotely in a different body lumen from the sensor, the implantable medical device configured to adjust cardiac pacing therapy delivered to the heart based at least in part on the data from the pressure sensor;

a control module operatively coupled to the implantable medical device; and

communication means for communicating pressure data from the pressure sensor to the control module, wherein the control module is adapted for relating the at least one of systolic pressure, diastolic pressure, pulse pressure, heart rate or pre-ejection period to a pre-programmed value, adjusting at least one cardiac pacing parameter relating to cardiac pacing therapy provided by the implantable medical device based on the relationship of the at least one of systolic pressure, diastolic pressure, pulse pressure, heart rate or pre-ejection period to the pre-programmed value, and repeating this process until the relationship is such that no adjustment is necessary.

2. The system of claim 1, wherein the at least one cardiac pacing parameter is one of timing, amplitude or site of electrical stimulation.

3. The system of claim 1, wherein the communication means includes a radio frequency communicator operatively coupled with the pressure sensor and the implantable medical device.

4. The system of claim 1, wherein the communication means includes an ultrasound communicator operatively coupled to the pressure sensor and the implantable medical device.

5. The system of claim 1, wherein the communication means includes an acoustic communicator operatively coupled with the pressure sensor and the implantable medical device.

6. The system of claim 1, wherein the communication means is a physical connection between the pressure sensor and the implantable medical device.

7. The system of claim 1, further including an external device in communication with the processor and the implantable medical device.

8. The system of claim 1, wherein the implantable medical device is one of a pulse generator, a pacemaker, a defibrillator or a drug pump.

9. The system of claim 1, further comprising an anchor for fixing the pressure sensor in the pulmonary artery.

10. The system of claim 1, further comprising:

a second sensor positioned within the heart and adapted for measuring a physiologic parameter; and

communication means for communicating data representative of the physiologic parameter to the control module, wherein the control module is adapted for adjusting an operating parameter of the implantable medical device based on the relationship of the at least one of systolic pressure, diastolic pressure, pulse pressure, heart rate or pre-ejection period to the pre-programmed value in conjunction with the physiologic parameter data.

11. A system for administering a therapeutic treatment, the system comprising:

a pressure sensor adapted for positioning in the pulmonary artery and collecting data representative of mean pulmonary artery pressure based on pressure in the pulmonary artery;

an implantable medical device including a lead located remotely in a different body lumen from the sensor, the implantable medical device configured to adjust cardiac pacing therapy delivered to the heart based at least in part on the data from the pressure sensor;

a control module operatively coupled to the implantable medical device; and

communication means for wirelessly communicating pressure data from the pressure sensor to the control module, wherein the control module is adapted for relating the mean pulmonary artery pressure to a pre-programmed value, adjusting at least one cardiac pacing parameter relating to cardiac pacing therapy provided by the implantable medical device based on the relationship of the mean pulmonary artery pressure to the pre-programmed value, the at least one cardiac pacing parameter including a timing or pacing amplitude parameter associated with the cardiac pacing therapy, and repeating this process until the relationship is such that no adjustment is necessary.

12. The system of claim 11, wherein the at least one cardiac pacing parameter further includes a site of electrical stimulation parameter.

13. The system of claim 11, wherein the at least one cardiac pacing parameter includes an AV delay parameter.

14. The system of claim 11, further including an external device in communication with the processor and the implantable medical device.

15. The system of claim 11, wherein the implantable medical device is one of a pulse generator, a pacemaker, a defibrillator or a drug pump.

16. The system of claim 11, further comprising an anchor for fixing the pressure sensor in the pulmonary artery.

17. The system of claim 11, further comprising:

a second sensor positioned within the heart and adapted for measuring a physiologic parameter; and

communication means for communicating data representative of the physiologic parameter to the control module, wherein the control module is adapted for adjusting an operating parameter of the implantable medical device based on the relationship of the mean pulmonary artery pressure to the pre-programmed value in conjunction with the physiologic parameter data.

18. The system of claim 11, wherein said communication means is configured to wirelessly communicate data to the control module.

19. A method of administering a cardiac rhythm management therapy to the heart, the method comprising:

sensing a number of pulmonary artery pressure readings from within the pulmonary artery;

determining a mean pulmonary artery pressure from the pulmonary artery pressure readings;

communicating data representative of the mean pulmonary artery pressure from the sensor to an implantable medical device;

comparing the mean pulmonary artery pressure to a pre-programmed value;

limiting increases in the heart'"'"'s pacing rate by sending a cardiac pacing signal to the heart based at least in part on the sensed data representative of mean pulmonary artery pressure to maintain the mean pulmonary artery pressure below the pre-programmed value; and

repeating the process until the relationship between the mean pulmonary artery pressure and the pre-programmed value is such that no adjustment is necessary.