Multiple electrode vectors for implantable cardiac treatment devices

• US 7,953,489 B2
• Filed: 11/30/2009
• Issued: 05/31/2011
• Est. Priority Date: 11/21/2001
• Status: Expired due to Fees

• Current Assignee: Cameron Incorporated (Schlumberger NV)
• Original Assignee: Cameron Incorporated (Schlumberger NV)
• Inventors: Bardy, Gust H., Warren, Jay A.
• Primary Examiner(s): Getzow; Scott M
• Application Number:
  US12/627,861
• Publication Number:
  US 20100076513A1
• Time in Patent Office: 547 Days
• Field of Search: 607 4- 28, 600508-523
• US Class Current: 607/27
• CPC Class Codes: A61B 5/076 Permanent implantations telemetry using implanted circuitry A61B5/0031; implanted stimulators for therapy A61N1/3605, A61N1/362, A61N1/372
• CPC Class Codes: A61B 5/276 Protection against electrode failure
• CPC Class Codes: A61B 5/283 Invasive
• CPC Class Codes: A61B 5/304 Switching circuits
• CPC Class Codes: A61B 5/318 Heart-related electrical modalities, e.g. electrocardiography [ECG]
• CPC Class Codes: A61B 5/7207 of noise induced by motion artifacts
• CPC Class Codes: A61N 1/3622 comprising two or more electrodes co-operating with different heart regions
• CPC Class Codes: A61N 1/3925 Monitoring; Protecting

Abstract

The implantable cardiac treatment system of the present invention is capable of choosing the most appropriate electrode vector to sense within a particular patient. In certain embodiments, the implantable cardiac treatment system determines the most appropriate electrode vector for continuous sensing based on which electrode vector results in the greatest signal amplitude, or some other useful metric such as signal-to-noise ratio (SNR). The electrode vector possessing the highest quality as measured using the metric is then set as the default electrode vector for sensing. Additionally, in certain embodiments of the present invention, a next alternative electrode vector is selected based on being generally orthogonal to the default electrode vector. In yet other embodiments of the present invention, the next alternative electrode vector is selected based on possessing the next highest quality metric after the default electrode vector. In some embodiments, if analysis of the default vector is ambiguous, the next alternative electrode vector is analyzed to reduce ambiguity.

Claims

1. A method of cardiac signal analysis in an implantable medical device comprising a canister and a lead system, the implantable medical device including at least first, second and third electrodes, and being configured such that one or more pairs of electrodes can be selected for use in cardiac signal sensing, the method comprising:

selecting and using a default sensing vector defined between a selected pair of electrodes to monitor a patient'"'"'s cardiac rhythm;

analyzing, monitoring and, if necessary, treating the patient'"'"'s cardiac rhythm by;

a) detecting electrical events using the selected default sensing vector

b) determining whether detected events appear to be cardiac beats by performing beat validation of the detected events;

c) using those events that appear to be cardiac beats to identify whether the patient is experiencing a malignant cardiac rhythm; and

d) if a malignant cardiac rhythm is identified, delivering electrical stimulus to the patient;

if detected events consistently fail to pass beat validation, determining the default sensing vector is unsuitable for cardiac signal analysis; and

in response to determining that the default sensing vector is unsuitable, selecting a different default sensing vector.

2. The method of claim 1 wherein:

step a) comprises establishing at least a first event representation for a detected event using signal captured using the default sensing vector; and

step c) comprises comparing the first event representation to a default vector event template using a correlation analysis.

3. The method of claim 2 wherein:

step a) further comprises establishing a second event representation for the detected event using signal captured using a vector other than the default sensing vector; and

step c) comprises determining whether the correlation analysis of the first event representation yields;

a determinative result, in which case the second event representation is not used to characterize the cardiac rhythm of the patient;

or

an ambiguous result, in which case step b) further comprises comparing the second event representation to another event template to characterize the cardiac rhythm of the patient.

4. The method of claim 1 further comprising determining whether a previously selected default vector continues to be valid by:

attempting to form a template using captured signals, the template being indicative of normal cardiac signals; and

if the attempt to form a template succeeds, determining that the previously selected default vector continues to be valid;

or

if the attempt to form a template fails, determining that the previously selected default vector is no longer valid.

5. The method of claim 4 wherein:

step a) comprises establishing at least a first event representation for a detected event using signal captured using the default sensing vector; and

step c) comprises comparing the first event representation to a default vector event template using a correlation analysis.

6. An implantable cardiac therapy system (ICTS) comprising:

a canister housing operational circuitry for the system, the operational circuitry configured to receive and analyze cardiac signals of a patient and, when indicated by sensed conditions, to provide therapeutic energy for the patient, the housing comprising at least one electrode disposed thereon; and

a lead electrode assembly coupled to the canister with at least first and second lead electrodes disposed thereon and electrically coupled to operational circuitry;

wherein the operational circuitry is configured to perform a method comprising;

selecting and using a default sensing vector defined between a selected pair of electrodes to monitor a patient'"'"'s cardiac rhythm;

analyzing, monitoring and, if necessary, treating the patient'"'"'s cardiac rhythm by;

a) detecting electrical events using the selected default sensing vector

b) determining whether detected events appear to be cardiac beats by performing beat validation of the detected events;

c) using those events that appear to be cardiac beats to identify whether the patient is experiencing a malignant cardiac rhythm; and

d) if a malignant cardiac rhythm is identified, delivering electrical stimulus to the patient;

if detected events consistently fail to pass beat validation, determining the default sensing vector is unsuitable for cardiac signal analysis; and

in response to determining that the default sensing vector is unsuitable, selecting a different default sensing vector.

7. The ICTS of claim 6 wherein the operational circuitry is configured such that:

step a) comprises establishing at least a first event representation for a detected event using signal captured using the default sensing vector; and

step c) comprises comparing the first event representation to a default vector event template using a correlation analysis.

8. The ICTS of claim 7 wherein the operational circuitry is further configured such that the method will be performed as follows:

step a) further comprises establishing a second event representation for the detected event using signal captured using a vector other than the default sensing vector; and

step c) comprises determining whether the correlation analysis of the first event representation yields;

a determinative result, in which case the second event representation is not used to characterize the cardiac rhythm of the patient;

or

an ambiguous result, in which case step b) further comprises comparing the second event representation to another event template to characterize the cardiac rhythm of the patient.

9. The ICTS of claim 6 wherein the lead electrode assembly further comprises a stimulus electrode disposed between the first and second lead electrodes wherein the operational circuitry is electrically coupled to the stimulus electrode to provide cardiac electrical therapy, when indicated, using the stimulus electrode.

10. The ICTS of claim 6 wherein the operational circuitry is further configured to determine whether a previously selected default vector continues to be valid by:

attempting to form a template using captured signals, the template being indicative of normal cardiac signals; and

if the attempt to form a template succeeds, determining that the previously selected default vector continues to be valid;

or

if the attempt to form a template fails, determining that the previously selected default vector is no longer valid.

11. The ICTS of claim 10 wherein:

step a) comprises establishing at least a first event representation for a detected event using signal captured using the default sensing vector; and

step c) comprises comparing the first event representation to a default vector event template using a correlation analysis.

12. An implantable cardiac therapy system (ICTS) comprising:

a plurality of implantable electrodes configured for tissue interfacing to capture electrical signals;

operational circuitry configured to receive and analyze cardiac signals of a patient from the implantable electrodes, the operational circuitry further configured to provide electrical stimulus therapy to the patient when indicated; and

a housing for containing the operational circuitry for implantation in a patient;

wherein the operational circuitry is configured to perform a method comprising;

selecting and using a default sensing vector defined between a selected pair of electrodes to monitor a patient'"'"'s cardiac rhythm;

analyzing, monitoring and, if necessary, treating the patient'"'"'s cardiac rhythm by;

a) detecting electrical events using the selected default sensing vector

b) determining whether detected events appear to be cardiac beats by performing beat validation of the detected events;

c) using those events that appear to be cardiac beats to identify whether the patient is experiencing a malignant cardiac rhythm; and

d) if a malignant cardiac rhythm is identified, delivering electrical stimulus to the patient;

if detected events consistently fail to pass beat validation, determining the default sensing vector is unsuitable for cardiac signal analysis; and

in response to determining that the default sensing vector is unsuitable, selecting a different default sensing vector.

13. The ICTS of claim 12 wherein the operational circuitry is configured such that:

step a) comprises establishing at least a first event representation for a detected event using signal captured using the default sensing vector; and

step c) comprises comparing the first event representation to a default vector event template using a correlation analysis.

14. The ICTS of claim 13 wherein the operational circuitry is configured such that:

step a) further comprises establishing a second event representation for the detected event using signal captured using a vector other than the default sensing vector; and

step c) comprises determining whether the correlation analysis of the first event representation yields;

a determinative result, in which case the second event representation is not used to characterize the cardiac rhythm of the patient;

or

an ambiguous result, in which case step b) further comprises comparing the second event representation to another event template to characterize the cardiac rhythm of the patient.

15. The ICTS of claim 12 wherein the operational circuitry and electrodes are coupled together such that at least two of the plurality of electrodes serve as therapy delivery electrodes, and therapy output by the operational circuitry is directed through the therapy delivery electrodes.

16. The ICTS of claim 12 wherein the operational circuitry is further configured to determine whether a previously selected default vector continues to be valid by:

attempting to form a template using captured signals, the template being indicative of normal cardiac signals; and

if the attempt to form a template succeeds, determining that the previously selected default vector continues to be valid;

or

if the attempt to form a template fails, determining that the previously selected default vector is no longer valid.

17. The ICTS of claim 16 wherein:

step a) comprises establishing at least a first event representation for a detected event using signal captured using the default sensing vector; and

step c) comprises comparing the first event representation to a default vector event template using a correlation analysis.