Method and apparatus for treatment of skin using RF and ultrasound energies

• US 7,955,262 B2
• Filed: 07/26/2005
• Issued: 06/07/2011
• Est. Priority Date: 07/26/2005
• Status: Active Grant

• Current Assignee: Syneron Medical Limited (Syneron Incorporated)
• Original Assignee: Syneron Medical Limited (Syneron Incorporated)
• Inventors: Rosenberg, Avner
• Primary Examiner(s): Jung; Unsu
• Assistant Examiner(s): Laryea; Lawrence N
• Application Number:
  US11/189,129
• Publication Number:
  US 20070038156A1
• Time in Patent Office: 2,142 Days
• Field of Search: 606 37- 41, 606/27, 600/439, 601/2, 601/3, 607/99, 607/101
• US Class Current: 600/439
• CPC Class Codes: A61B 18/14 Probes or electrodes therefor
• CPC Class Codes: A61B 2018/00452 Skin
• CPC Class Codes: A61B 2018/00994 combining two or more different kinds of non-mechanical energy or combining one or more non-mechanical energies with ultrasound
• CPC Class Codes: A61N 2007/0078 with multiple treatment transducers
• CPC Class Codes: A61N 7/02 Localised ultrasound hyperthermia hyperthermia in general A61F7/00

Abstract

A system and method for treating skin. The System comprises one or more ultrasound transducers and one or more pairs of RF electrodes. The ultrasound transducers are adapted to focus ultrasound energy at one or more focal volumes in the skin. The RF electrodes are adapted to deliver RF energy to the one or more focal volumes. The method comprises heating the skin to a first temperature at one or more focal volumes in the skin by focusing ultrasound energy at the one or more focal volumes. The focal regions are then heated to a second temperature, the second temperature being higher than the first temperature, by generating an RF current in a region of the skin containing the focal regions.

Claims

1. A system for generating a guided current path in a skin volume, said system comprising:

(a) at least one transducer configured to focus ultrasound energy at least one focal volume in the skin and heat said volume so as to raise the volume electrical conductivity;

(b) at least a pair of RF electrodes configured to deliver RF energy to the same focal volume; and

(c) a control unit configured to enable an RF current generated by the RF energy to flow between the pair of RF electrodes through a central part of the heated focal volume,

wherein the parameters of the RF energy are selected from the group consisting of a frequency of an RF voltage between 100 KHz and 100 MHz, an intensity of the RF voltage, and a duration of the RF energy, and

wherein the ultrasound energy has a frequency between 500 KHz and 50 MHz.

2. The system according to claim 1, wherein the control unit is configured to:

(a) activate at least one of the ultrasound transducer for a first predetermined amount of time; and

(b) apply an RF voltage to the RF electrodes for a second predetermined amount of time.

3. The system according to claim 2, wherein said RF electrodes are configured to generate at least one of spatially matching or time matching with said skin volume affected by ultrasound electric field.

4. The system according to claim 3, wherein said space matching electric field generated by the RF electrodes covers the focal volume of the ultrasound transducer.

5. The system according to claim 3, wherein said time matching electric field generated by the RF electrodes is the time between the focusing of the ultrasound energy and delivery of the RF energy to the skin.

6. The system according to claim 1, wherein the at least one ultrasound transducer is configured to focus ultrasound energy to at least one focal volume located in a dermis layer of the skin.

7. The system according to claim 1, further comprising a cooling system cooling the skin surface.

8. The system according to claim 1, further comprising an applicator configured to be applied to the skin surface, the applicator containing the ultrasound transducer and the RF electrodes.

9. The system according to claim 8, wherein at least one pair of the RF electrodes and at least one of the ultrasound transducer are contained in the applicator in which the at least one ultrasound transducer is located between the pair of RF electrodes configured to generate electric current in the same ultrasound heated skin volume.

10. The system according to claim 1, wherein at least one of the focal volumes is located between 0.2 mm and 5 mm below the skin surface.

11. The system according to claim 10, wherein at least one of the focal volumes is located between 0.2 mm to 2 mm below the skin surface.

12. The system according to claim 1, wherein a lateral width of at least one of the focal volumes is between 0.05 mm to 1 mm.

13. The system according to claim 12, wherein the lateral width of at least one of the focal volumes is between 0.1 mm to 0.3 mm.

14. The system according to claim 1, wherein a lateral spacing between the focal volumes is between 0.3 mm to 3 mm.

15. The system according to claim 14, wherein the lateral spacing between focal volumes is between the 0.5 mm to 1 mm.

16. The system according to claim 1, wherein a longitudinal length of the focal volumes between the RF electrodes is between 1 mm to 20 mm.

17. The system according to claim 16, wherein the longitudinal length of the focal volumes between the RF electrodes is between 3 mm to 10 mm.

18. The system according to claim 1, wherein a electric field generated by the RF electrode coincides with the focal volume of the ultrasound transducer.

19. The system according to claim 1, wherein the delivery of the RF energy to at least one of the focal volumes of the skin immediately follows the focusing of the ultrasound energy to the same focal volumes.

20. A method for treating skin, said method comprising:

(a) heating at least one focal volume of the skin by focusing ultrasound energy at said focal volume to a first temperature, said temperature being sufficient to raise an electrical conductivity of said focal volume; and

,

(b) increasing further the temperature of the same focal volume to a second temperature, the second temperature being higher than the first temperature, by guiding an RF current through said focal volumes with raised temperature;

wherein the RF current is generated by an RF energy frequency between 100 KHz and 100 MHz,

wherein the ultrasound energy has a frequency between 500 KHz and 50 MHz, and

wherein the RF current flows through a central part of the heated focal volume.

21. The method according to claim 20, wherein at least one of the focal volumes is located in a subcutaneous region of the skin.

22. The method according to claim 20, further comprising cooling the skin surface.

23. The method according to claim 20, wherein at least one of the focal volumes is located between 0.2 mm and 5 mm below the skin surface.

24. The method according to claim 23, wherein at least one of the focal volumes is located between 0.2 mm to 2 mm below the skin surface.

25. The method according to claim 20, wherein a lateral width of at least one of the focal volumes is between 0.05 mm to 1 mm.

26. The method according to claim 25, wherein the lateral width of one or more of the focal volumes is between 0.1 mm to 0.3 mm.

27. The method according to claim 20, wherein a lateral spacing between focal volumes is between 0.3 mm to 3 mm.

28. The method according to claim 27, wherein the lateral spacing between focal volumes is between 0.5 mm to 1 mm.

29. The method according to claim 20, wherein a length of the focal volumes between the RF electrodes is between 1 mm to 20 mm.

30. The method according to claim 29, wherein the length of the focal volumes between the RF electrodes is between 3 mm to 10 mm.

31. A system for skin treatment, said system comprising:

(a) at least one ultrasound transducer configured to focus ultrasound energy into at least one focal volume in the skin operative to raise the electrical conductivity of said volume and generate at least one guided RF current path;

(b) at least one pair of RF electrodes configured to deliver RF energy to pass along a longitudinal direction into the same volumes forming said guided RF current paths; and

(c) a control unit configured to enable an RF current generated by the RF energy to flow between the pair of RF electrodes through a central part of the focal volume,

wherein the RF energy has a frequency between 100 KHz and 100 MHz, and

wherein the ultrasound energy has a frequency between 500 KHz and 50 MHz.

32. A method for treating skin, said method comprising:

(a) heating the skin to a first temperature at one or more focal volumes in the skin by focusing ultrasound energy at the one or more focal volumes;

(b) heating the one or more focal volumes to a second temperature, the second temperature being higher than the first temperature, by generating an RF current passing along the longitudinal direction of the same focal volumes; and

(c) controlling the RF current to flow through a central part of the heated focal volume,

wherein the RF current is generated by an RF energy frequency between 100 KHz and 100 MHz, and

wherein the ultrasound energy has a frequency between 500 KHz and 50 MHz.

33. A method for generating a guided current path in the skin, said method comprising:

(a) applying to the skin surface at least one ultrasound energy focused into the skin and operating to heat a focal volume to a first temperature sufficient to raise the temperature of said focal volume;

(b) increasing the temperature of the same focal volume by applying to said skin surface RF energy and guiding an induced RF current into the same focal volumes with raised temperature by the ultrasound energy; and

(c) controlling the RF current to flow through a central part of the heated focal volume,

wherein the RF energy frequency is between 100 KHz and 100 MHz, and

wherein the ultrasound energy has a frequency between 500 KHz and 50 MHz.

34. A method for skin treatment, said method comprising:

a) applying to the skin to be treated a system including;

(i) at least one ultrasound transducer adapted to focus ultrasound energy at one or more focal volumes in the skin and heat said volumes such that their electrical conductivity is increased in said at one or more focal volumes in the skin; and

(ii) at least one pair of RF electrodes adapted to deliver RF energy to the same focal volume;

b) generating at least one guided RF current path in said volume; and

c) conducting RF induced current through the guided RF current path;

wherein the RF current flows through a central part of the heated focal volume,

wherein the RF energy frequency is between 100 KHz and 100 MHz, and

wherein the ultrasound energy frequency is between 500 KHz and 50 MHz.

35. A system for skin treatment, said system comprising:

a) at least one pair of RF electrodes configured to induce RF current in a guiding channel produced in the skin; and

b) at least one focused ultrasound source applied between the RF electrodes,

wherein the ultrasound source, by heating the skin to a temperature higher than the surrounding skin, creates in the skin a single guiding channel for the RF current, said channel extending between the RF electrodes,

wherein the RF current is generated by an RF energy frequency between 100 KHz and 100 MHz, and

wherein the ultrasound source generates an ultrasound energy frequency between 500 KHz and 50 MHz,

said system further comprising;

c) a control unit configured to enable the RF current to flow between the pair of RF electrodes through a central part of the single guiding channel.

36. A system for skin treatment, said system comprising:

a) at least one ultrasound transducer configured to generate a single elongated focal zone in a volume of the skin and raise the temperature of the focal zone to a first temperature higher than the temperature of the surrounding skin; and

b) a single pair of RF electrodes extending along the elongated focal zone and driven by a single RF power supply, said RF electrodes being configured to be applied to the skin and generate, in the elongated focal zone, a time and spatially matching the ultrasound generated elongated focal zone electric field and heat the same elongated focal zone to a second temperature higher than the first temperature,

wherein application of the ultrasound energy heats the elongated focal zone and generates a guided channel further heated by RF energy applied to the elongated focal zone,

wherein the RF energy has a frequency between 100 KHz and 100 MHz, and

wherein the ultrasound energy has a frequency between 500 KHz and 50 MHz,

said system further comprising;

c) a control unit configured to enable an RF current generated by the RF energy to flow between the pair of RF electrodes through a central part of the elongated focal zone.

37. A system for skin treatment, said system comprising:

a) one or more cylindrical ultrasound transducers configured to produce in the skin one or more cylindrical focal volumes with each transducer heating a respective focal volume;

b) a plurality of RF electrodes with a 1-dimensional or 2-dimensional structure interlacing with the ultrasound transducers and configured to be applied to the skin to heat further the same cylindrical focal volumes heated by the ultrasound transducer; and

c) a control unit configured to enable an RF current generated by an RF energy to flow between the plurality of RF electrodes through a central part of the heated cylindrical focal volume,

wherein the RF electrodes produce the RF energy having a frequency between 100 KHz and 100 MHz, and

wherein the ultrasound transducer produces an ultrasound energy having a frequency between 500 KHz and 50 MHz.