Polymer-bioceramic composite implantable medical device with different types of bioceramic particles
First Claim
1. A stent comprising structural elements fabricated at least in part from a bioceramic/polymer composite, the composite having a plurality of bioceramic particles dispersed within a biodegradable polymer, the plurality of bioceramic particles comprising at least two types of bioceramic particles, a first type which includes acidic or hydrophilic particles that increases the degradation rate of the polymer and a second type which includes basic particles that decreases the degradation rate of the polymer.
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Accused Products
Abstract
Implantable medical devices fabricated from polymer/bioceramic composites with different types of bioceramic particles are disclosed. The plurality of bioceramic particles can include acidic particles and basic particles, the acidic particles and basic particles having different particle size distributions. The degradation of a selected type of particle can be reduced or prevented during a selected time frame by encapsulating some or all of the selected type of particles with a bioabsorbable polymer.
388 Citations
36 Claims
- 1. A stent comprising structural elements fabricated at least in part from a bioceramic/polymer composite, the composite having a plurality of bioceramic particles dispersed within a biodegradable polymer, the plurality of bioceramic particles comprising at least two types of bioceramic particles, a first type which includes acidic or hydrophilic particles that increases the degradation rate of the polymer and a second type which includes basic particles that decreases the degradation rate of the polymer.
- 14. A stent comprising structural elements fabricated from a bioceramic/polymer composite, the composite having a plurality of bioceramic particles dispersed within a biodegradable polymer, the plurality of bioceramic particles comprising acidic particles and basic particles, the acidic particles and basic particles having different particle size distributions.
- 26. A stent comprising structural elements fabricated from a bioceramic/polymer composite, the composite having a plurality of bioceramic particles dispersed within a biodegradable polymer, the plurality of bioceramic particles comprising at least two types of particles, a first type which includes acidic or hydrophilic particles that increases the degradation rate of the polymer and a second type which includes basic particles that decreases the degradation rate of the polymer wherein the degradation of a selected type of particle is reduced or prevented during a selected time frame by encapsulating some or all of the selected type of particles with an encapsulating bioabsorbable polymer.
Specification