Systems for removing dimethyl sulfoxide (DMSO) or related compounds or odors associated with same

• US 7,955,418 B2
• Filed: 09/11/2006
• Issued: 06/07/2011
• Est. Priority Date: 09/12/2005
• Status: Active Grant

• Current Assignee: Abela Pharmaceuticals, Inc.
• Original Assignee: Abela Pharmaceuticals, Inc.
• Inventors: Claussen, Harvey L., Cozean, Colette
• Primary Examiner(s): LAWRENCE JR, FRANK M
• Application Number:
  US12/066,485
• Publication Number:
  US 20080251081A1
• Time in Patent Office: 1,730 Days
• Field of Search: 951/35, 951/37, 951/41, 961/175, 961/34, 961/54, 128/203.29, 128/206.12, 128/205.27, 128/205.25, 128/206.21, 128/205.26, 423/244.01, 55D/IG.35, 422/56, 422/120
• US Class Current: 95/135
• CPC Class Codes: A41D 13/1115 with a horizontal pleated pocket
• CPC Class Codes: A41D 13/1123 with a duckbill configuration
• CPC Class Codes: A41D 13/1192 with antimicrobial agent
• CPC Class Codes: A61L 9/014 containing sorbent material, e.g. activated carbon
• CPC Class Codes: A61M 16/0087 Environmental safety or protection means, e.g. preventing explosion
• CPC Class Codes: A61M 16/0093 by adsorption, absorption or filtration
• CPC Class Codes: A61M 16/06 Respiratory or anaesthetic masks
• CPC Class Codes: A61M 16/105 Filters A61M16/047, A61M16/22 take precedence; water traps A61M16/08
• CPC Class Codes: A61M 16/1055 bacterial
• CPC Class Codes: A61M 16/1065 in the expiratory path
• CPC Class Codes: A61M 16/1075 by influencing the temperature A61M16/1045 takes precedence
• CPC Class Codes: A61M 16/208 Non-controlled one-way valves, e.g. exhalation, check, pop-off non-rebreathing valves
• CPC Class Codes: A61M 2205/7527 liquophilic, hydrophilic
• CPC Class Codes: A62B 23/00 Filters for breathing-protection purposes gas-filters in general B01D
• CPC Class Codes: B01D 2253/202 Polymeric adsorbents
• CPC Class Codes: B01D 2253/311 Porosity, e.g. pore volume
• CPC Class Codes: B01D 2257/306 Organic sulfur compounds, e.g. mercaptans
• CPC Class Codes: B01D 2257/90 Odorous compounds not provided for in groups B01D2257/00 - B01D2257/708
• CPC Class Codes: B01D 2257/91 Bacteria; Microorganisms
• CPC Class Codes: B01D 2259/4533 for medical purposes
• CPC Class Codes: B01D 2259/4541 : for portable use, e.g. gas masks
• CPC Class Codes: B01D 53/02 : by adsorption, e.g. preparative gas chromatography solid sorbent compositions B01J20/00, preparation of inorganic compounds or elements C01
• CPC Class Codes: B01D 53/04 : with stationary adsorbents B01D53/025 takes precedence
• CPC Class Codes: B01D 53/508 : by treating the gases with solids
• CPC Class Codes: B01J 20/28085 : being more than 50 nm, i.e. macropores

Abstract

Preferred embodiments of the invention relate to systems for removing dimethyl sulfoxide (DMSO) or related compounds, or odors associated with same. The systems include adsorbents, odor adsorbing fabrics, masks, clean air members and clean air supply assemblies.

Claims

1. An adsorbent for adsorbing dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said compounds, comprising:

an inner layer, an intermediate layer, and an outer layer,

wherein said inner layer comprises adsorbing core particles;

wherein said adsorbing core particles adsorb dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said compounds;

wherein said intermediate layer contacts said inner layer and said outer layer; and

wherein said outer layer comprises a porous coating; and

an indicator for indicating the presence of dimethyl sulfoxide (DMSO) or related compounds.

2. The adsorbent of claim 1, wherein said indicator comprises permanganate.

3. The adsorbent of claim 1, wherein said indicator is colored, and is adapted to decrease in color or intensity as dimethyl sulfoxide (DMSO) or related compounds are removed.

4. The adsorbent according to claim 1, wherein said adsorbing core particles are selected from the group consisting of one or more of the following:

activated carbon, an inorganic oxide, a compound having ion exchange capacity, an ion exchange resin, and a chemical deodorizer.

6. The adsorbent according to claim 1 or claim 5, wherein said outer layer consists only of a porous coating.

7. The adsorbent according to claim 1 or claim 5, wherein said outer layer comprises a polymer selected from the group consisting of one or more of the following:

a fluororesin, a polyamide resin, a polyimide resin, a polyester resin, a polystyrene resin, a polyolefin resin, a polycarbonate resin, a polysulfone resin, an acrylic resin, a cellulose resin, a vinyl chloride resin, a polyacetal resin, a polyurethane resin and a copolymer or derivative thereof.

8. The adsorbent according to claim 1 or claim 5, wherein said outer layer comprises a polymer selected from the group consisting of one or more of the following:

polytetrafluoroethylene, polyhexafluoropropylene, polydifluoroethylene, polyvinylidene fluoride, polyvinyl fluoride, and a copolymer or derivative thereof.

9. The adsorbent according to claim 1 or claim 5, wherein said porous coating has a thickness of about 0.01 μ

m to about 1,000 μ

m.

10. The adsorbent according to claim 1 or claim 5,, wherein said porous coating has an average pore diameter of about 0.01 μ

m to about 500 μ

m.

11. The adsorbent according claim 1 or claim 5, wherein said porous coating has a porosity of about 3% to about 90%.

15. A clean air member for removal of dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said dimethyl sulfoxide (DMSO) or related compounds comprising the adsorbent according to claim 1 or claim 5.

16. A clean air supply assembly for removal of dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said dimethyl sulfoxide (DMSO) or related compounds comprising the adsorbent according to claim 1 or claim 5.

5. An adsorbent for adsorbing dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said compounds, comprising:

an inner layer, an intermediate layer, and an outer layer,

wherein said inner layer comprises adsorbing core particles;

wherein said adsorbing core particles adsorb dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said compounds;

wherein said intermediate layer contacts said inner layer and said outer layer,

wherein said outer layer comprises a porous coating, and

wherein said intermediate layer comprises a metal compound and a water-soluble organic material disposed between the core particles and the porous coating.

12. A method for removing dimethyl sulfoxide (DMSO) metabolites, comprising contacting said metabolites with an adsorbent, said absorbent comprising:

an inner layer, an intermediate layer, and an outer layer,

wherein said inner layer comprises adsorbing core particles;

wherein said adsorbing core particles adsorb dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said compounds;

wherein said intermediate layer contacts said inner layer and said outer layer; and

wherein said outer layer comprises a porous coating.

13. The method of claim 12, wherein said dimethyl sulfoxide (DMSO) metabolites are produced by an individual receiving dimethyl sulfoxide (DMSO) treatment.

22. A method according to claim 12 or claim 14, wherein said adsorbent further comprises an indicator for indicating the presence of dimethyl sulfoxide (DMSO) or related compounds.

23. The method according to claim 22, wherein said indicator comprises permanganate.

24. The method according to claim 22, wherein said indicator is colored, and is adapted to decrease in color or intensity as dimethyl sulfoxide (DMSO) or related compounds are removed.

25. A method according to claim 12 or claim 14, wherein said adsorbing core particles are selected from the group consisting of one or more of the following:

activated carbon, an inorganic oxide, a compound having ion exchange capacity, an ion exchange resin, and a chemical deodorizer.

14. A method for removing odors associated with dimethyl sulfoxide (DMSO) or related compounds, comprising exposing said odors to an adsorbent, said absorbent comprising:

an inner layer, an intermediate layer, and an outer layer,

wherein said inner layer comprises adsorbing core particles;

wherein said adsorbing core particles adsorb dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said compounds;

wherein said intermediate layer contacts said inner layer and said outer layer; and

wherein said outer layer comprises a porous coating.

17. An apparatus for removing dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said dimethyl sulfoxide (DMSO) or related compounds from the exhaust outlet of a medical respiratory ventilator, wherein said apparatus comprises:

a gas scavenging device comprising an adsorbent, said adsorbent comprising;

an inner layer, an intermediate layer, and an outer layer,

wherein said inner layer comprises absorbing core particles;

wherein said adsorbing core particles adsorb dimethyl sulfoxide (DMSO) or related compounds, or the odor associated with said compounds;

wherein said intermediate layer contacts said inner layer and said outer layer;

wherein said adsorbing core particles adsorb dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said compounds;

wherein said intermediate layer contacts said inner layer and said outer layer,

wherein said outer layer comprises a porous coating, and

wherein said gas scavenging device is connected to said exhaust outlet.

18. A face mask for reducing exposure of dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said dimethyl sulfoxide (DMSO) or related compounds comprising an adsorbent, said adsorbent comprising:

an inner layer, an intermediate layer, and an outer layer,

wherein said inner layer comprises adsorbing core particles;

wherein said adsorbing core particles adsorb dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said compounds;

wherein said intermediate layer contacts said inner layer and said outer layer, wherein said outer layer comprises a porous coating.

19. A face mask for reducing exposure of dimethyl sulfoxide (DMSO) or related compounds, or the odors associated with said dimethyl sulfoxide (DMSO) or related compounds comprising:

an outer shield layer comprising a synthetic fiber;

a copper layer comprising a fiber and powdered copper;

a carbon layer comprising a fiber and activated carbon;

a chemical layer comprising a fiber and one or more, odor absorbing chemicals; and

a facial layer comprising a synthetic fiber.

20. The face mask according to claim 19, wherein said face mask comprises an exhale valve.

21. The face mask according to claim 19, wherein said face mask is a duckbill mask.