Method and apparatus for conducting microwave assisted organic reactions with gas-phase reactants
First Claim
Patent Images
1. A method of accelerating organic reactions that include a gas phase reactant, the method comprising:
- conducting a hydrogenation reaction selected from the group consisting of olefin hydrogenation, alkyne hydrogenation, carbobenzyloxy deprotection, and reductive amination, using the steps of;
introducing a microwave transparent reaction vessel containing an organic compound to be hydrogenated into a microwave cavity;
purging the reaction vessel containing the organic compound to be hydrogenated;
charging the reaction vessel with hydrogen gas in an amount that is at least stoichiometric with respect to the amount of the organic compound to be hydrogenated;
applying a continuous single mode of microwave radiation within the cavity and to the vessel and the organic compound in the vessel until the organic compound is hydrogenated to a desired yield; and
venting the vessel at the completion of the hydrogenation reaction.
1 Assignment
0 Petitions
Accused Products
Abstract
A method of accelerating the hydrogenation of organic compounds is provided. The method includes positioning an microwave transparent reaction vessel containing at least one reactant suitable for hydrogenation in a microwave cavity, purging the reaction vessel, charging the reaction vessel with hydrogen gas, and applying a continuous single mode of microwave radiation within the cavity and to the vessel and its contents for a time sufficient to effect a chemical change in the reactants.
-
Citations
12 Claims
-
1. A method of accelerating organic reactions that include a gas phase reactant, the method comprising:
-
conducting a hydrogenation reaction selected from the group consisting of olefin hydrogenation, alkyne hydrogenation, carbobenzyloxy deprotection, and reductive amination, using the steps of; introducing a microwave transparent reaction vessel containing an organic compound to be hydrogenated into a microwave cavity; purging the reaction vessel containing the organic compound to be hydrogenated; charging the reaction vessel with hydrogen gas in an amount that is at least stoichiometric with respect to the amount of the organic compound to be hydrogenated; applying a continuous single mode of microwave radiation within the cavity and to the vessel and the organic compound in the vessel until the organic compound is hydrogenated to a desired yield; and venting the vessel at the completion of the hydrogenation reaction. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
-
Specification