Glucose biosensor and method
First Claim
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1. A glucose biosensor comprising:
- a laminated body having a fluid sample inlet end and an electrical contact end;
a fluid sample inlet;
a substantially flat sample chamber in communication between said fluid sample inlet and a vent opening, said sample chamber being adapted to collect a fluid sample through said fluid sample inlet;
a GOD-based glucose electrode;
a GDH-based glucose electrode; and
a reference electrode wherein said GOD-based glucose electrode, said GDH-based glucose electrode and said reference electrode are within said sample chamber.
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Abstract
A system for more accurately measuring glucose in a sample includes a first glucose-sensing electrode incorporating a quantity of glucose oxidase, a second glucose-sensing electrode incorporating a quantity of PQQ-glucose dehydrogenase, a reference electrode, and means for selecting between a first glucose measurement made with the first glucose-sensing electrode and a second glucose measurement made with the second glucose-sensing electrode.
131 Citations
15 Claims
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1. A glucose biosensor comprising:
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a laminated body having a fluid sample inlet end and an electrical contact end; a fluid sample inlet; a substantially flat sample chamber in communication between said fluid sample inlet and a vent opening, said sample chamber being adapted to collect a fluid sample through said fluid sample inlet; a GOD-based glucose electrode; a GDH-based glucose electrode; and a reference electrode wherein said GOD-based glucose electrode, said GDH-based glucose electrode and said reference electrode are within said sample chamber. - View Dependent Claims (2, 3, 4, 5)
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6. A system for more accurately measuring glucose in a sample comprising:
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a first glucose-sensing electrode incorporating a quantity of glucose oxidase; a second glucose-sensing electrode incorporating a quantity of glucose dehydrogenase; a reference electrode; and means for selecting between a first glucose measurement made with said first glucose-sensing electrode in a sample and a second glucose measurement made with said second glucose-sensing electrode in said sample. - View Dependent Claims (7, 8, 9, 10, 11)
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12. A method for determining glucose concentration in a blood sample more accurately, said method comprising:
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making a first measurement of said glucose concentration of said blood sample using a first glucose electrode incorporating glucose oxidase; making a second measurement of said glucose concentration of said blood sample using a second glucose electrode incorporating glucose dehydrogenase; calculating the difference between said first measurement and said second measurement; and selecting one of said first measurement and said second measurement based on said calculated difference when said difference is compared to a predefined value. - View Dependent Claims (13, 14)
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15. A disposable glucose sensor comprising:
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a sensor body having an open well forming a test chamber; a GOD-based glucose electrode, a GDH-based glucose electrode and reference/counter electrode disposed within said open well; and electrical contacts on one end of said sensor body.
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Specification