Automated implantation system for radioisotope seeds

• US 7,959,548 B2
• Filed: 03/22/2005
• Issued: 06/14/2011
• Est. Priority Date: 06/05/2000
• Status: Expired due to Fees

• Current Assignee: Theragenics Corporation (Juniper Investment Co. LLC)
• Original Assignee: Core Oncology, Inc.
• Inventors: Hoedeman, George M., Berkey, John J., Elliott, Daniel M.
• Primary Examiner(s): Gilbert; Samuel G
• Application Number:
  US11/086,779
• Publication Number:
  US 20050209499A1
• Time in Patent Office: 2,275 Days
• Field of Search: 600 1- 8
• US Class Current: 600/3
• CPC Class Codes: A61M 37/0069 Devices for implanting pellets, e.g. markers or solid medicaments for introducing of radioactive sources for interstitial radiation therapy, i.e. brachytherapy A61N5/1027
• CPC Class Codes: A61N 2005/1008 Apparatus for temporary insertion of sources, e.g. afterloaders
• CPC Class Codes: A61N 2005/1009 Apparatus for loading seeds into magazines or needles
• CPC Class Codes: A61N 2005/101 Magazines or cartridges for seeds
• CPC Class Codes: A61N 2005/1011 Apparatus for permanent insertion of sources
• CPC Class Codes: A61N 5/1007 Arrangements or means for the introduction of sources into the body
• CPC Class Codes: A61N 5/1027 Interstitial radiation therapy
• CPC Class Codes: A61N 5/103 Treatment planning systems

Abstract

An automated implantation system assists the implantation of low dose radioisotope seeds in a patient as part of a brachytherapy procedure. A Z-axis automated motion control system and an X-Y axis automated motion control system control a needle assembly. The X-Y axis automated motion control system positions an insertion axis of the needle assembly relative to the patient. The Z-axis automated motion control system selectively moves the needle assembly along the insertion axis to implant at least one radioisotope seed. This process is repeated for a plurality of locations on a base plane perpendicular to the insertion axis. Preferably, the radioisotope seeds are contained in a replaceable cartridge and the needle assembly is also replaceable.

Claims

1. An automated implantation system for implanting low dose radioisotope seeds in a patient as part of a brachytherapy procedure comprising:

a seed cartridge having an aperture and containing at least a plurality of radioisotope seeds preloaded into the seed cartridge, wherein the seed cartridge is locked into an automated implantation system during the operation of the automated implantation system;

a needle assembly;

a Z-axis automated motion control system that selectively moves at least the needle assembly along an insertion axis and into the patient and selectively ejects radioisotope seeds from the seed cartridge into the needle assembly; and

a force sensor that senses forces on the needle assembly along the insertion axis and is operably connected to at least the Z-axis automated motion control system.

2. The automated implantation system of claim 1, wherein the force sensor senses whether the needle assembly encounters resistance above an expected force for piercing tissue when the Z-axis automated motion control system advances the needle assembly and, in response, the Z-axis automated motion control system stops advancing the needle assembly.

3. The automated implantation system of claim 1, wherein the force sensor senses whether the needle assembly has advanced into a non-tissue region and, in response, a user interface operably connected to the Z-axis automated motion control system provides an indication to a user that the needle assembly has advanced into the non-tissue region.

4. An automated implantation system for implanting low dose radioisotope seeds in a patient as part of a brachytherapy procedure comprising:

a seed cartridge having an aperture and containing at least a plurality of radioisotope seeds preloaded into the cartridge;

a needle assembly;

a Z-axis automated motion control system that selectively moves at least the needle assembly along an insertion axis and into the patient and selectively ejects radioisotope seeds from the seed cartridge into the needle assembly; and

a force sensor that senses forces on the needle assembly along the insertion axis and is operably connected to at least the Z-axis automated motion control system, wherein the force sensor senses whether the needle assembly encounters resistance above an expected force for piercing tissue when the Z-axis automated motion control system advances the needle assembly and, in response, the Z-axis automated motion control system stops advancing the needle assembly; and

wherein the Z-axis automated motion control system is mounted in a compliant mount and the force sensor is mounted at a rear of the Z-axis automated motion control system, the compliant mount providing a minimum travel distance in the event that the needle assembly encounters resistance above the expected force for piercing tissue that forms a safety buffer to allow the needle assembly to retract.

5. An automated implantation system for implanting low dose radioisotope seeds in a patient as part of a brachytherapy procedure comprising:

a seed cartridge having an aperture and containing at least a plurality of radioisotope seeds preloaded into the cartridge;

a needle assembly;

a Z-axis automated motion control system that selectively moves at least the needle assembly along an insertion axis and into the patient and selectively ejects radioisotope seeds from the seed cartridge into the needle assembly; and

a force sensor that senses forces on the needle assembly along the insertion axis and is operably connected to at least the Z-axis automated motion control system, wherein the force sensor senses whether the needle assembly encounters resistance above an expected force for piercing tissue when the Z-axis automated motion control system advances the needle assembly and, in response, the Z-axis automated motion control system stops advancing the needle assembly, and wherein the force sensor comprises a load cell mounted in a compliant mount at a rear of the needle assembly, the compliant mount providing with a minimum travel distance in the event that the needle encounters resistance above the expected force for piercing tissue that forms a safety buffer to allow the needle to retract.