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Solvating system and sealant for medical use in the middle or inner ear

  • US 7,959,943 B2
  • Filed: 04/24/2007
  • Issued: 06/14/2011
  • Est. Priority Date: 05/10/2006
  • Status: Active Grant
First Claim
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1. A method for treating chronic otitis media and other bacterial ear conditions, which method comprises:

  • a) applying an aqueous solvating system comprising a metal ion sequestering agent and greater than 0.2 wt. % surfactant to a treatment site comprising a bacterial biofilm comprising an extracellular polysaccharide matrix attached or adhered to at least a portion of the middle or inner ear,b) detaching, removing or otherwise disrupting at least a part of the biofilm by solvating the extracellular polysaccharide matrix with the solvating system and then rinsing away the solvating system, and thenc) applying to the treatment site a protective layer of a polymeric film-forming sealant.

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