Method of recommending neurophysiological therapies
First Claim
1. A method for recommending treatment, comprising:
- a) providing;
i) a first set of quantified neurophysiologic information obtained from a patient having a behaviorally diagnosed psychiatric disorder;
ii) a second set of quantified neurophysiologic information obtained from at least one reference population of individuals, wherein said second information set comprises at least one therapy responsivity profile, wherein said profile includes a first treatment modality, wherein said first treatment modality is recommended independently of said diagnosed psychiatric disorder and associated symptoms;
b) comparing said first set of quantified neurophysiologic information with said second set of quantified neurophysiologic information by cluster analysis, under conditions such that a correlation between said patient and said at least one therapy responsivity profile is indicated, wherein said comparing is performed by a computer;
c) recommending said first treatment modality for said patient based upon said indicated correlation.
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Abstract
A method and system for utilizing neurophysiologic information obtained by techniques such as quantitative electroencephalography (QEEG), electrode recordings, MRI in appropriately matching patients with therapeutic entities is disclosed. The present invention enables utilization of neurophysiologic information, notwithstanding its weak correlation with extant diagnostic schemes for mental disorders, for safer and expeditious treatment for mental disorders, discovering new applications for therapeutic entities, improved testing of candidate therapeutic entities, inferring the presence or absence of a desirable response to a treatment, and deducing the mode of action of one or more therapeutic entities. In particular, methods for effectively comparing neurophysiologic information relative to a reference set are disclosed along with database-based tools for deducing therapeutic entity actions on particular patients such that these tools are readily accessible to remote users.
28 Citations
12 Claims
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1. A method for recommending treatment, comprising:
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a) providing; i) a first set of quantified neurophysiologic information obtained from a patient having a behaviorally diagnosed psychiatric disorder; ii) a second set of quantified neurophysiologic information obtained from at least one reference population of individuals, wherein said second information set comprises at least one therapy responsivity profile, wherein said profile includes a first treatment modality, wherein said first treatment modality is recommended independently of said diagnosed psychiatric disorder and associated symptoms; b) comparing said first set of quantified neurophysiologic information with said second set of quantified neurophysiologic information by cluster analysis, under conditions such that a correlation between said patient and said at least one therapy responsivity profile is indicated, wherein said comparing is performed by a computer; c) recommending said first treatment modality for said patient based upon said indicated correlation. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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Specification