Methods and systems for stimulating a motor cortex of the brain to treat a medical condition

• US 7,962,219 B2
• Filed: 01/11/2010
• Issued: 06/14/2011
• Est. Priority Date: 02/25/2005
• Status: Active Grant

• Current Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Original Assignee: Boston Scientific Neuromodulation Corporation (Boston Scientific Corporation)
• Inventors: Carbunaru, Rafael, Jaax, Kristen N., Whitehurst, Todd K.
• Primary Examiner(s): Layno; Carl H
• Assistant Examiner(s): Gedeon; Brian T
• Application Number:
  US12/685,161
• Publication Number:
  US 20100114192A1
• Time in Patent Office: 519 Days
• Field of Search: 607/45
• US Class Current: 607/45
• CPC Class Codes: A61N 1/36082 Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
• CPC Class Codes: A61N 1/37205 Microstimulators, e.g. implantable through a cannula

Abstract

Methods of treating a medical condition include applying at least one stimulus to a motor cortex within a brain of a patient with an implanted system control unit in accordance with one or more stimulation parameters. Systems for treating a medical condition include a system control unit implanted within the patient that is configured to apply at least one stimulus to a motor cortex within a brain of a patient in accordance with one or more stimulation parameters.

Claims

1. A method of treating a patient with a medical condition, comprising:

implanting a microstimulator within an opening extending completely through a skull of said patient, wherein the microstimulator resides within the opening;

routing an electrical lead or a catheter from said microstimulator through the opening to portion of motor cortex;

generating a stimulus in accordance with one or more stimulation parameters using said microstimulator; and

applying said stimulus to said portion of said motor cortex of said patient adjacent said opening via said electrical lead or said catheter, thereby treating said medical condition.

2. The method of claim 1, further comprising sensing at least one indicator related to said medical condition and using said at least one sensed indicator to adjust said one or more stimulation parameters.

3. The method of claim 1, wherein said stimulus comprises electrical stimulation.

4. The method of claim 3, wherein said one or more stimulation parameters includes one or more of a frequency, a pulse width, a duty cycle, a burst pattern, and an amplitude.

5. The method of claim 1, wherein said stimulus comprises a drug infusion.

6. The method of claim 5, wherein said one or more stimulation parameters includes one or more of an amount of drug infusion, a rate of drug infusion, and a frequency of drug infusion.

7. The method of claim 1, wherein said microstimulator comprises a capsule, and one or both of electrical circuitry and a drug pump contained within said capsule.

8. The method of claim 7, wherein said microstimulator comprises a power source contained within said capsule, said power source supplying energy to said one or both of said electrical circuitry and said drug pump.

9. The method of claim 8, wherein said microstimulator comprises a programmable memory contained within said capsule, where in said programmable memory stores said one or more stimulation parameters, the method further comprising wirelessly transmitting a command from an external control device to said microstimulator that adjusts said stored one or more stimulation parameters.

10. The method of claim 8, wherein said medical condition is a headache.

11. The method of claim 1, wherein the opening comprises a main hole extending only partially into the skull, and a smaller hole extending from the main hole through the remainder of the skull, wherein the microstimulator is implanted within the main hole, and the electrical lead or catheter extends through the smaller hole.