Arterial pressure-based, automatic determination of a cardiovascular parameter
First Claim
1. A method for determining a cardiovascular parameter of a subject comprising:
- sensing, over a period corresponding to at least one cardiac cycle, an input signal that indicates arterial blood pressure;
computing, using at least a portion of a processing system, a set of pressure-weighted time values, each corresponding to the product of a sensing time, relative to an initial time, and arterial pressure at the sensing time; and
estimating the cardiovascular parameter as a function of the set of pressure-weighted time values.
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Abstract
One or more cardiovascular parameters is estimated as a function of the arterial pressure waveform, in particular, using at least one statistical moment of a discrete representation pressure waveform having an order greater than one. Arterial compliance, the exponential pressure decay constant, vascular resistance, cardiac output, and stroke volume are examples of cardiovascular parameters that can be estimated using various aspects of the invention. In one embodiment of the invention, not only are the first four moments (mean, standard deviation, skewness, and kurtosis) of the pressure waveform used to estimate the cardiovascular parameter(s) of interest, but also heart rate, statistical moments of a set of pressure-weighted time values, and certain anthropometric patient measurements such as age, sex, body surface area, etc.
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Citations
20 Claims
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1. A method for determining a cardiovascular parameter of a subject comprising:
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sensing, over a period corresponding to at least one cardiac cycle, an input signal that indicates arterial blood pressure; computing, using at least a portion of a processing system, a set of pressure-weighted time values, each corresponding to the product of a sensing time, relative to an initial time, and arterial pressure at the sensing time; and estimating the cardiovascular parameter as a function of the set of pressure-weighted time values. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A system for determining a cardiovascular parameter of a subject comprising:
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a processing system sensing, over a period corresponding to at least one cardiac cycle, an input signal that indicates arterial blood pressure; computer-executable code for computing a set of pressure-weighted time values, each corresponding to the product of a sensing time, relative to an initial time, and arterial pressure at the sensing time; and
for estimating the cardiovascular parameter as a function of the set of pressure-weighted time values. - View Dependent Claims (15, 16, 17, 18, 19, 20)
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Specification