Biosensor and ultrasonic method of making a biosensor
First Claim
Patent Images
1. A method for making a biosensor, comprising the steps of:
- providing a substrate having a region for receiving a sample;
dispensing a liquid substance on a surface of the region for receiving a sample; and
applying ultrasonic vibrations at an angle of about 60-90 degrees to the bottom of the substrate to quickly and uniformly spread the liquid substance on the surface of the region for receiving a sample.
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Abstract
There is provided a test strip for testing a fluid sample, including a sample cavity configured to receive the fluid sample and an ultrasonically-spread reagent layer arranged on at least one surface of the sample cavity. There is also provided a method for making a biosensor, including providing a substrate having a region for receiving a sample; dispensing a liquid substance on at least one surface of the region for receiving a sample; and subjecting the substrate to ultrasonic vibrations to quickly and uniformly spread the liquid substance on the at least one surface of the region for receiving a sample.
25 Citations
27 Claims
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1. A method for making a biosensor, comprising the steps of:
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providing a substrate having a region for receiving a sample; dispensing a liquid substance on a surface of the region for receiving a sample; and applying ultrasonic vibrations at an angle of about 60-90 degrees to the bottom of the substrate to quickly and uniformly spread the liquid substance on the surface of the region for receiving a sample. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A method for manufacturing a plurality of biosensors, comprising:
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arranging a plurality of test strip substrates into an array; providing each test strip substrate in the array with a sample cavity; dispensing a liquid solution on a surface of the sample cavity of each test strip in the array; and subjecting the sample cavity of each test strip in the array to ultrasonic vibrations to quickly and uniformly spread the liquid solution on the surface of the sample cavity of each test strip in the array, wherein the ultrasonic vibrations are applied at an angle of about 60-90 degrees to the bottom of the sample cavity of each test strip in the array. - View Dependent Claims (11, 12, 13, 14, 15, 16, 17, 18)
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19. A method for making a plurality of test strips, comprising the steps of:
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arranging a plurality of test strips into an array, each test strip comprising (1) a base layer, (2) a spacer layer arranged on the base layer, and (3) a sample cavity defined by the base and spacer layers; dispensing a liquid reagent layer on a surface of the sample cavity; and passing the array over an ultrasonic generator to subject the sample cavity of each test strip to ultrasonic vibrations to quickly and uniformly spread the liquid reagent layer, and wherein the passing step comprises subjecting the sample cavity of each test strip in the array to ultrasonic vibrations that are between about 60-90 degrees to the surface of the sample cavity. - View Dependent Claims (20, 21, 22, 23, 24, 25, 26, 27)
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Specification