Screening system and method for analyzing a plurality of biosensors
First Claim
1. A screening system capable of controlling at least one of movement and storage of a sensor carrier therein to ensure there is a substantially constant temperature gradient present across at least a portion of the sensor carrier, further comprising a temperature equilibration system which includes a temperature compensation body on which the sensor carrier is stored for a predetermined amount of time to ensure there is a substantially constant temperature gradient present across the at least a portion of the sensor carrier, and a temperature sensor which measures an incoming temperature of the sensor carrier and then the measured incoming temperature is used to calculate the predetermined amount of time that the sensor carrier needs to be placed on said temperature compensation body to ensure there is a substantially constant temperature gradient present across the at least a portion of the sensor carrier.
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Accused Products
Abstract
A screening device and a method are described herein which can automatically handle and measure (interrogate) a plurality of sensor carriers (i.e., multiwell plates, microplates) with multi-dimensionally arranged, temperature-compensated or temperature-compensatable optical sensors, while maintaining a substantially constant temperature gradient for a relatively long period of time around the optical sensors where temperature compensation has been performed on the sensor carriers.
63 Citations
18 Claims
- 1. A screening system capable of controlling at least one of movement and storage of a sensor carrier therein to ensure there is a substantially constant temperature gradient present across at least a portion of the sensor carrier, further comprising a temperature equilibration system which includes a temperature compensation body on which the sensor carrier is stored for a predetermined amount of time to ensure there is a substantially constant temperature gradient present across the at least a portion of the sensor carrier, and a temperature sensor which measures an incoming temperature of the sensor carrier and then the measured incoming temperature is used to calculate the predetermined amount of time that the sensor carrier needs to be placed on said temperature compensation body to ensure there is a substantially constant temperature gradient present across the at least a portion of the sensor carrier.
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3. A screening system, comprising:
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a temperature equilibration system which includes a temperature compensation body on which a sensor carrier is stored for a predetermined amount of time to ensure there is a substantially constant temperature gradient across at least a portion of the sensor carrier; a measurement system which interrogates one or more sensors located within the sensor carrier when there is still the substantially constant temperature gradient present across at least a portion of the sensor carrier; and a temperature sensor which measures an incoming temperature of the sensor carrier and then the measured incoming temperature is used to calculate the predetermined amount of time that the sensor carrier needs to be placed on said temperature compensation body to ensure there is a substantially constant temperature gradient across the at least a portion of the sensor carrier. - View Dependent Claims (4)
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5. A screening system comprising:
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a measurement chamber; a take in/out mechanism which receives a sensor carrier and moves the sensor carrier to inside said measurement chamber, said measurement chamber contains at least the following; a handling system; a temperature equilibration system which has a plate holder with one or more layers where each of the layers has a plurality of temperature compensation bodies; a table which has a measurement nest; wherein said handling system takes the sensor carrier from said take in/out mechanism and places the sensor carrier onto one of the temperature compensation bodies to help equalize a temperature of the sensor carrier; and wherein said handling system after a period of time takes the sensor carrier from the one temperature compensation body of said temperature equilibration system and places the sensor carrier into the measurement nest of said table; a measurement system which interrogates one or more sensors located within the sensor carrier when the sensor carrier is located on the measurement nest of the table; and a control unit for controlling said take in/out mechanism, said handling system, said temperature equilibration system, said table and said measurement system to perform a measurement analysis on the sensors located within the sensor carrier. - View Dependent Claims (6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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Specification