Device and method for controlling injection of liquid embolic composition

• US 7,976,527 B2
• Filed: 10/24/2007
• Issued: 07/12/2011
• Est. Priority Date: 10/17/1997
• Status: Expired due to Fees

• Current Assignee: Covidien LP (Medtronic Plc)
• Original Assignee: Micro Therapeutics, Inc. (Medtronic Plc)
• Inventors: Wallace, George, Jones, Michael, Walker, Blair D., Perl, John II, Greff, Richard J., Greene, George R., Cragg, Andrew H.
• Primary Examiner(s): Lucchesi; Nicholas D
• Assistant Examiner(s): Bouchelle; Laura A
• Application Number:
  US11/923,495
• Publication Number:
  US 20080045922A1
• Time in Patent Office: 1,357 Days
• Field of Search: 604/508, 604/523, 604/500, 604/507, 606/108, 606/191, 606/200, 623/1.11, 623/1.15, 623/1.16
• US Class Current: 604/508
• CPC Class Codes: A61B 17/00491 Surgical glue applicators surgical adhesives A61L24/00; two-component delivery syringes A61M5/19
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 17/12168 having a mesh structure A61B17/1214 takes precedence
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12177 comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
• CPC Class Codes: A61B 17/12186 liquid materials adapted to be injected
• CPC Class Codes: A61B 17/1219 expandable in contact with liquids
• CPC Class Codes: A61B 17/12195 comprising a curable material
• CPC Class Codes: A61B 2017/00495 for two-component glue
• CPC Class Codes: A61B 2017/00876 magnetic
• CPC Class Codes: A61B 2017/00893 pharmaceutically effective
• CPC Class Codes: A61B 2017/1205 Introduction devices
• CPC Class Codes: A61B 2017/12059 Joint of soluble material
• CPC Class Codes: A61B 2017/12063 electrolytically detachable
• CPC Class Codes: A61M 2025/0036 with more than four lumina
• CPC Class Codes: A61M 2025/004 characterized by lumina being arranged circumferentially
• CPC Class Codes: A61M 25/00 Catheters; Hollow probes dilators A61M29/00; peritoneal catheters A61M1/285; tracheal tubes A61M16/04; for drainage A61M27/00; for uterus, vagina or rectum A61M31/00 ; for measuring or testing A61B; materials for catheters A61L29/00
• CPC Class Codes: A61M 25/0028 characterized by features relating to at least one lumen located at the proximal part of the catheter, e.g. alterations in lumen shape or valves catheter hubs A61M25/0097
• CPC Class Codes: A61M 25/0097 : characterised by the hub connectors A61M39/10

Abstract

A liquid embolic delivery system is provided for trapping an injected liquid embolic composition to prevent the liquid embolic from solidifying or otherwise passing outside of an embolization area. The delivery system includes a catheter for delivery of a liquid embolic composition and a containment member positioned at a distal end of the catheter which is shaped to trap the liquid embolic composition delivered through the lumen of the catheter. The containment member is formed as a brush, nest, sponge, swab, flexible sack, or other shape into and around which the liquid embolic composition is injected. The liquid embolic composition is trapped or meshes with the containment member during solidification containing the liquid embolic and preventing the embolic composition from passing into the blood stream.

Claims

1. A liquid embolic delivery system comprising:

a catheter having a distal end, a proximal end, and a lumen for delivery of a liquid embolic composition to a cavity wherein said distal end is detachable; and

a detachment area on the catheter for detaching the distal end of the catheter after solidification of the liquid embolic composition;

wherein said liquid embolic composition comprises a biocompatible polymer combined with a biocompatible solvent;

wherein said polymer is ethylene vinyl alcohol copolymer and the solvent is dimethyl sulfoxide (DMSO).

3. The method of claim 1, further comprising removing the proximal end of the catheter from the body.

2. A method of delivering a liquid embolic composition at an embolization site within a body comprising:

delivering a liquid embolic composition to an embolization site within a body with a catheter having a distal end and a proximal end, exposing the liquid embolic composition to blood in the embolization site; and

detaching the distal end of the catheter after solidification of the liquid embolic composition to release the catheter from a mass of solidified embolic composition.