Event triggered infection monitoring

• US 7,976,534 B2
• Filed: 07/28/2009
• Issued: 07/12/2011
• Est. Priority Date: 04/19/2007
• Status: Active Grant

• Current Assignee: Medtronic Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Incorporated (Medtronic Plc)
• Inventors: Gerber, Martin T., Rondoni, John C.
• Primary Examiner(s): Sirmons; Kevin C
• Assistant Examiner(s): Hall; Deanna K
• Application Number:
  US12/510,595
• Publication Number:
  US 20090299153A1
• Time in Patent Office: 714 Days
• Field of Search: 600/549, 604/890.1, 604 65- 67, 604/131, 604/891.1, 604/502, 604/288.01
• US Class Current: 604/891.1
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body
• CPC Class Codes: A61M 2205/18 with alarm
• CPC Class Codes: A61M 2205/3368 Temperature
• CPC Class Codes: A61M 2205/3523 using telemetric means
• CPC Class Codes: A61M 2205/3561 local, e.g. within room or hospital
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/16836 by sensing tissue properties at the infusion site, e.g. for detecting infiltration detecting tissue temperature for diagnostic purposes A61M39/0247

Abstract

Implantable medical devices include a sensor module capable of detecting an indicator of infection in proximity to the device. The sensor module is activated following a detection of an event associated with the device, such as, for example, refill of an implantable infusion device or implantation. The sensor module is deactivated two or more hours following activation. Methods include detecting a first event associated with an implanted medical device; activating a sensor module of the implanted medical device at or after the detection of the first event; deactivating the sensor module two hours or more after the sensor module is activated; and determining whether information regarding the indicator of infection is indicative of an infection.

Claims

1. A method carried out by an implanted medical device or a system that includes the implanted medical device, comprising:

detecting a first event associated with the implanted medical device;

activating a sensor module of the implanted medical device at or after the detection of the first event, the sensor module capable of obtaining and transmitting information regarding an indicator of infection;

deactivating the sensor module two hours or more after the sensor module is activated; and

determining whether the information regarding the indicator of infection is indicative of an infection,

wherein the implanted device is a refillable infusion device and wherein detecting the first event comprises detecting an event associated with refilling the device.

2. The method of claim 1, wherein detecting the first event comprises receiving instructions from a programmer that a refill event has commenced or is completed.

3. The method of claim 1, wherein activating the sensor module comprises providing power to a sensor from a power source of the implanted device.

4. The method of claim 1, wherein activating the sensor module comprises activating a circuit to store information provided by a sensor in memory of the implanted device.

5. The method of claim 1, wherein activating the sensor module comprises activating the module such that the module provides sensed information in discrete time intervals.

6. The method of claim 1, wherein deactivating the sensor module two hours or more after the sensor module is activated comprises deactivating the sensor module between two hours and 90 days after the sensor module is activated.

7. The method of claim 1, wherein determining whether information regarding the indicator of infection is indicative of an infection is determined in the implantable medical device.

8. The method of claim 1, further comprising sending the information regarding the indicator of infection to a second device, wherein determining whether information regarding the indicator of infection is indicative of an infection is determined in the second device.

9. The method of claim 1, further comprising:

detecting a second even associated with the implanted medical device; and

reactivating the sensor module at or after the detection of the second event.

10. The method of claim 9, wherein detecting the second event comprises detecting an event associated with a subsequent refilling the device.

11. The method of claim 10, wherein detecting the event associated with the subsequent refilling the device comprises receiving instructions from a programmer that the subsequent refill event has commenced or is completed.

12. The method of claim 9, further comprising deactivating the sensor module two or more hours after the reactivation of the sensor module.

13. The method of claim 1, wherein the sensor module is capable of obtaining and transmitting information regarding temperature.

14. The method of claim 1, wherein the sensor module is capable of obtaining and transmitting information regarding pH or impedance.

15. The method of claim 1, further comprising issuing an alert if the indicator of infection is indicative of an infection.

18. The method of claim 1, wherein detecting the first event comprises detecting insertion of a needle into a refill port of the device.

19. The method of claim 9, wherein detecting the second event comprises detecting insertion of a needle into a refill port of the device.

16. A non-transitory computer readable medium containing instructions that when implemented cause an implantable refillable infusion device to (i) detect an event associated with refilling the implanted medical device;

(ii) activate a sensor module of the implanted medical device at or after the detection of the event, the sensor module capable of detecting an indicator of infection;

(ii) deactivate the sensor module two hours or more after the sensor module is activated; and

(iii) determine whether information regarding the indicator of infection is indicative of an infection.

17. An implantable refillable infusion device comprising the computer-readable media of claim 16.