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System and method for denaturing and fixing collagenous tissue

  • US 7,976,539 B2
  • Filed: 07/19/2005
  • Issued: 07/12/2011
  • Est. Priority Date: 03/05/2004
  • Status: Active Grant
First Claim
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1. A method for modifying a valve in a subject'"'"'s body, comprising:

  • endoluminally advancing an elongate flexible instrument to within a vicinity of a valve in a subject'"'"'s body;

    heating a tissue mass located in a vicinity of the valve to a temperature sufficient to shrink the tissue mass, thereby modifying the shape or position of a valve to modify flow through the valve; and

    introducing a biocompatible fixative into the tissue mass after heating the tissue mass, to retain shrinkage or tightening of the tissue mass and to retain the modified shape or position of the valve.

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