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Drug delivery to a joint

  • US 7,976,858 B2
  • Filed: 01/13/2005
  • Issued: 07/12/2011
  • Est. Priority Date: 01/13/2004
  • Status: Active Grant
First Claim
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1. A method of intra-articular drug delivery, comprising:

  • identifying an attachment zone in a synovial joint, wherein the attachment zone comprises a non-articulating portion of bone and/or cartilage within the synovial joint; and

    percutaneously affixing a drug release device in the attachment zone, the drug release device comprising a base affixable in the attachment zone, a sustained-release drug carrier, and a drug, the device positioned so that the device releases the drug into the synovial fluid of the synovial joint, and so that agitation of the synovial fluid facilitates elution of the drug from the drug release device.

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