Mammalian sweet taste receptors
First Claim
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1. An isolated receptor, wherein the receptor comprises a first polypeptide and a second polypeptide, wherein the first polypeptide has at least 93% amino acid sequence identity to SEQ ID NO:
- 20, or at least 94% amino acid sequence identity to SEQ ID NO;
23, and wherein the second polypeptide has at least 92% amino acid sequence identity to SEQ ID NO;
8.
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Abstract
The present invention provides isolated nucleic acid and amino acid sequences of sweet taste receptors comprising two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet taste receptors.
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Citations
29 Claims
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1. An isolated receptor, wherein the receptor comprises a first polypeptide and a second polypeptide, wherein the first polypeptide has at least 93% amino acid sequence identity to SEQ ID NO:
- 20, or at least 94% amino acid sequence identity to SEQ ID NO;
23, and wherein the second polypeptide has at least 92% amino acid sequence identity to SEQ ID NO;
8. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29)
- 20, or at least 94% amino acid sequence identity to SEQ ID NO;
Specification