Charged particle beam irradiation system and method of extracting charged particle beam

• US 7,977,656 B2
• Filed: 09/06/2006
• Issued: 07/12/2011
• Est. Priority Date: 09/07/2005
• Status: Expired due to Fees

• Current Assignee: Hitachi, Ltd.
• Original Assignee: Hitachi, Ltd.
• Inventors: Totake, Satoshi, Fujimaki, Hisataka
• Primary Examiner(s): Johnston; Phillip A.
• Application Number:
  US11/515,920
• Publication Number:
  US 20070051905A1
• Time in Patent Office: 1,770 Days
• Field of Search: 250/492.3
• US Class Current: 250/492.3
• CPC Class Codes: A61N 2005/1087 Ions; Protons
• CPC Class Codes: A61N 5/1042 with spatial modulation of the radiation beam within the treatment head
• CPC Class Codes: G21K 1/043 changing time structure of beams by mechanical means, e.g. choppers, spinning filter wheels
• CPC Class Codes: G21K 1/10 Scattering devices; Absorbing devices; Ionising radiation filters
• CPC Class Codes: H05H 7/10 Arrangements for ejecting particles from orbits

Abstract

A charged particle beam irradiation system includes an accelerator for accelerating a charged particle beam, a beam irradiation apparatus having a beam energy modulator and arranged for irradiating an object with the charged particle beam extracted from the accelerator and having passed the beam energy modulator, which is rotated and whose thickness in the axial direction differs in the rotational direction, and a controller for controlling the extraction intensity of the charged particle beam extracted from the accelerator, while the charged particle beam is being extracted, on the basis of the rotational angle of the beam energy modulator.

Claims

1. A charged particle beam irradiation system comprising:

a synchrotron for accelerating a charged particle beam, the synchrotron including a radio frequency applying device for beam extraction;

a beam irradiation apparatus having a beam energy modulator and arranged for irradiating an object with the charged particle beam extracted from said synchrotron and having passed said beam energy modulator, the beam energy modulator being rotated and a thickness thereof in an axial direction differing in a rotational direction; and

a controller for controlling the extraction intensity of the charged particle beam extracted from the synchrotron by controlling an amplitude of a radio frequency signal supplied to the radio frequency applying device on the basis of a rotational angle of the beam energy modulator in the rotational direction, the extraction intensity being controlled to vary among different levels on the basis of the rotational angle of the beam energy modulator during a period after a start of the extraction of the charged particle beam and before a stop of the extraction of the charged particle beam while the charged particle beam is being extracted.

2. The charged particle beam irradiation system according to claim 1, further comprising:

an angle detector for detecting the rotational angle of the beam energy modulator,

wherein the controller controls the extraction intensity of the charged particle beam extracted from the synchrotron on the basis of the rotational angle detected by the angle detector.

3. The charged particle beam irradiation system according to claim 1, further comprising:

a storage device for storing a plurality of extraction intensity set values of charged particle beams extracted from the synchrotron, the extraction intensity set values corresponding to a plurality of rotational angles of the beam energy modulator,

wherein the controller controls the extraction intensity of the charged particle beam on the basis of one of the extraction intensity set values selected from the storage device according to the rotational angle of the beam energy modulator.

6. The charged particle beam irradiation system according to claim 1, wherein the thickness of the beam energy modulator in the axial direction changes in the rotational direction due to a structure provided with a plurality of steps.

7. The charged particle beam irradiation system according to claim 1, wherein the beam energy modulator includes a blade, the thickness of the blade in the axial direction differing in the rotational direction.

12. The charged particle beam irradiation system according to claim 1, wherein the controller further controls the period for extracting the charged particle beam by starting and stopping the beam extraction on the basis of the rotational angle of the beam energy modulator.

14. The charged particle beam irradiation system according to claim 7, wherein, when an ion beam having energy that is lower than the energy to which the shape of the beam energy modulator is optimized is transmitted to pass though the beam energy modulator, the controller reduces the extraction intensity of the ion beam passing through an area where the blade thickness is small compared to the extraction intensity of the ion beam passing through other areas.

15. The charged particle beam irradiation system according to claim 7, wherein, when an ion beam having energy that is higher than the energy to which the shape of the beam energy modulator is optimized is transmitted to pass through the beam energy modulator, the controller reduces the extraction intensity of the ion beam passing through a flat section of the blade of the beam energy modulator where the thickness is small compared to the extraction intensity of the ion beam passing through a flat section of the blade of the beam energy modulator where the thickness is great.

4. A charged particle beam irradiation system comprising:

a synchrotron for accelerating a charged particle beam, the synchrotron including a radio frequency applying device for beam extraction;

a beam irradiation apparatus having a beam energy modulator and arranged for irradiating an object with the charged particle beam extracted from said synchrotron and having passed said beam energy modulator, the beam energy modulator being rotated and a thickness thereof in an axial direction differing in a rotational direction; and

a controller for controlling the amplitude of a radio frequency signal supplied to the radio frequency applying device on the basis of a rotational angle of the beam energy modulator in the rotational direction, the amplitude being controlled to vary among different levels on the basis of the rotational angle of the beam energy modulator during a period after a start of the extraction of the charged particle beam and before a stop of the extraction of the charged particle beam while the charged particle beam is being extracted.

5. The charged particle beam irradiation system according to claim 4, further comprising:

an angle detector for detecting the rotational angle of the beam energy modulator,

wherein the controller controls the amplitude of the radio frequency signal on the basis of the rotational angle detected by the angle detector.

8. A charged particle beam irradiation system comprising:

a synchrotron for accelerating a charged particle beam, the synchrotron including a radio frequency applying device for beam extraction;

a beam irradiation apparatus having a beam energy modulator and arranged for irradiating an object with the charged particle beam extracted from said synchrotron and having passed said beam energy modulator, the beam energy modulator being rotated and a thickness thereof in an axial direction differing in a rotational direction; and

a controller for controlling the extraction intensity of the charged particle beam extracted from the synchrotron by controlling an amplitude of a radio frequency signal supplied to the radio frequency applying device on the basis of the thickness of the beam energy modulator in the axial direction, the extraction intensity being controlled to vary among different levels on the basis of the thickness of the beam energy modulator during a period after a start of the extraction of the charged particle beam and before a stop of the extraction of the charged particle beam while the charged particle beam is being extracted.

10. The charged particle beam irradiation system according to claim 8, wherein the thickness of the beam energy modulator is determined on the basis of the rotational angle of the beam energy modulator.

9. A charged particle beam irradiation system comprising:

a synchrotron for accelerating a charged particle beam, the synchrotron including a radio frequency applying device for beam extraction;

a beam irradiation apparatus having a beam energy modulator and arranged for irradiating an object with the charged particle beam extracted from said synchrotron and having passed said beam energy modulator, the beam energy modulator being rotated and a thickness thereof in an axial direction differing in a rotational direction; and

a controller for controlling the amplitude of a radio frequency signal supplied to the radio frequency applying device on the basis of the thickness of the beam energy modulator in the axial direction, the amplitude being controlled to vary among different levels on the basis of the thickness of the beam energy modulator during a period after a start of the extraction of the charged particle beam and before a stop of the extraction of the charged particle beam while the charged particle beam is being extracted.

11. A charged particle beam irradiation system comprising:

a synchrotron for accelerating a charged particle beam, the synchrotron including a radio frequency applying device for beam extraction;

a beam irradiation apparatus having a beam energy modulator and arranged for irradiating an object with the charged particle beam extracted from said synchrotron and having passed said beam energy modulator, the beam energy modulator being rotated and a thickness thereof in an axial direction differing in a rotational direction; and

a controller for controlling the extraction intensity of the charged particle beam extracted from the synchrotron while the charged particle beam is being extracted, when an ion beam having energy different from the energy to which the shape of the beam energy modulator is optimized is incident on the beam energy modulator, the extraction intensity being controlled to vary among different levels by controlling an amplitude of a radio frequency signal supplied to the radio frequency applying device synchrotron on the basis of one of the rotational angle in the rotational direction or the thickness in the axial direction of the beam energy modulator during a period after a start of the extraction of the charged particle beam and before a stop of the extraction of the charged particle beam while the charged particle beam is being extracted.

13. A charged particle beam irradiation system comprising:

a synchrotron for accelerating a charged particle beam, the synchrotron including a radio frequency applying device for beam extraction;

a beam irradiation apparatus having a beam energy modulator and arranged for irradiating an object with the charged particle beam extracted from said synchrotron and having passed said beam energy modulator, the beam energy modulator being rotated and a thickness thereof in an axial direction differing in a rotational direction; and

a controller for outputting an extraction start signal and an extraction stop signal for starting and stopping the extraction of a charged particle beam orbiting the synchrotron and a control signal for controlling the extraction intensity of the charged particle beam extracted from the synchrotron by controlling an amplitude of a radio frequency signal supplied to the radio frequency applying device on the basis of the rotational angle of the beam energy modulator in the rotational direction, the extraction intensity being controlled to vary among different levels on the basis of the rotational angle of the beam energy modulator during a period after a start of the extraction of the charged particle beam and before a stop of the extraction of the charged particle beam while the charged particle beam is being extracted.

16. A method of extracting a charged particle beam, comprising the steps of:

accelerating a charged particle beam using a synchrotron, the synchrotron including a radio frequency applying device for beam extraction;

transmitting the charged particle beam extracted from the synchrotron to pass a rotating beam energy modulator, a thickness of the beam energy modulator in an axial direction differing in a rotational direction; and

controlling the extraction intensity of the charged particle beam extracted from the synchrotron by controlling an amplitude of a radio frequency signal supplied to the radio frequency applying device on the basis of the rotational angle of the beam energy modulator in the rotational direction, the extraction intensity being controlled to vary among different levels on the basis of the rotational angle of the beam energy modulator during a period after a start of the extraction of the charged particle beam and before a stop of the extraction of the charged particle beam while the charged particle beam is being extracted.

19. The method of extracting a charged particle beam according to claim 16, wherein the charged particle beam is extracted from the synchrotron on the basis of extraction intensity set values of charged particle beams corresponding to a plurality of rotational angles of the beam energy modulator.

20. The method of extracting a charged particle beam according to claim 16, wherein the extraction intensity of the charged particle beam extracted from the synchrotron is further controlled by starting and stopping beam extraction.

17. A method of extracting a charged particle beam, comprising the steps of:

accelerating a charged particle beam with a synchrotron, the synchrotron including a radio frequency applying device the beam extraction;

transmitting the charged particle beam extracted from the synchrotron to pass a rotating beam energy modulator, a thickness of the beam energy modulator in an axial direction differing in a rotational direction; and

controlling the extraction intensity of the charged particle beam extracted from the synchrotron by controlling an amplitude of a radio frequency signal supplied to the radio frequency applying device on the basis of a rotating time of the beam energy modulator in the rotational direction, the extraction intensity being controlled to vary among different levels on the basis of the rotating time of the beam energy modulator during a period after a start of the extraction of the charged particle beam and before a stop of the extraction of the charged particle beam while the charged particle beam is being extracted.

18. A method of extracting a charged particle beam, comprising the steps of:

accelerating a charged particle beam with a synchrotron;

modulating the amplitude of a radio frequency signal applied to a charged particle beam on the basis of a rotational angle of a beam energy modulator in a rotational direction while the charged particle beam is being extracted, the amplitude being modulated to vary among different levels on the basis of the rotational angle of the beam energy modulator during a period after a start of the extraction of the charged particle beam and before a stop of the extraction of the charged particle beam while the charged particle beam is being extracted;

applying the modulated radio frequency signal for extracting the charged particle beam from the accelerator; and

transmitting the extracted charged particle beam to pass a rotating beam energy modulator, the thickness of the beam energy modulator in an axial direction differing in the rotational direction.

21. A charged particle beam irradiation system comprising:

a synchrotron for accelerating a charged particle beam, the synchrotron including a radio frequency applying device for beam extraction;

a beam irradiation apparatus having a beam energy modulator and arranged for irradiating an object with the charged particle beam extracted from said synchrotron and transported through the beam irradiation apparatus along a beam axis and having passed said beam energy modulator, the beam energy modulator being rotated in a rotational direction around an axis of rotation extending in a direction along said beam axis and a thickness thereof in the axial direction differing in the rotational direction; and

a controller for controlling the extraction intensity of the charged particle beam extracted from the synchrotron by controlling an amplitude of a radio frequency signal supplied to the radio frequency applying device on the basis of a rotational angle of the beam energy modulator in the rotational direction, the extraction intensity being controlled to vary among different levels on the basis of the rotational angle of the beam energy modulator during a period after a start of the extraction of the charged particle beam and before a stop of the extraction of the charged particle beam while the charged particle beam is being extracted.

22. A charged particle beam irradiation system comprising:

a synchrotron for accelerating a charged particle beam, the synchrotron including a radio frequency applying device for beam extraction;

a beam irradiation apparatus having a beam energy modulator and arranged for irradiating an object with the charged particle beam extracted from said synchrotron and having passed said beam energy modulator, the beam energy modulator being rotated and the thickness thereof in the axial direction differing in the rotational direction, the beam energy modulator being used to control a width of a spread-out Bragg peak (SOBP); and

a controller for controlling the extraction intensity of the charged particle beam extracted from the synchrotron by controlling an amplitude of a radio frequency signal supplied to the radio frequency applying device on the basis of the rotational angle of the beam energy modulator, the extraction intensity being controlled while the charged particle beam is being extracted from the synchrotron before reaching the beam irradiation apparatus.

23. The charged particle beam irradiation system according to claim 22, further comprising:

an angle detector for detecting the rotational angle of the beam energy modulator,

wherein the controller controls the extraction intensity of the charged particle beam extracted from the synchrotron on the basis of the rotational angle detected by the angle detector.

25. The charged particle beam irradiation system according to claim 22, further comprising:

a storage device for storing a plurality of extraction intensity set values of charged particle beams extracted from the synchrotron, the extraction intensity set values corresponding to a plurality of rotational angles of the beam energy modulator,

wherein the controller controls the extraction intensity of the charged particle beam on the basis of one of the extraction intensity set values selected from the storage device according to the rotational angle of the beam energy modulator.

28. The charged particle beam irradiation system according to claim 22, wherein the thickness of the beam energy modulator in the axial direction changes in the rotational direction due to a structure provided with a plurality of steps.

29. The charged particle beam irradiation system according to claim 22, wherein the beam energy modulator includes a blade, the thickness of the blade in the axial direction differing in the rotational direction.

34. The charged particle beam irradiation system according to claim 22, wherein the controller controls the period for extracting the charged particle beam by starting and stopping the beam extraction on the basis of the rotational angle of the beam energy modulator.

36. The charged particle beam irradiation system according to claim 29, wherein, when an ion beam having energy that is lower than the energy to which the shape of the beam energy modulator is optimized is transmitted to pass though the beam energy modulator, the controller reduces the extraction intensity of the ion beam passing through an area where the blade thickness is small compared to the extraction intensity of the ion beam passing through other areas.

37. The charged particle beam irradiation system according to claim 29, wherein, when an ion beam having energy that is higher than the energy to which the shape of the beam energy modulator is optimized is transmitted to pass through the beam energy modulator, the controller reduces the extraction intensity of the ion beam passing through a flat section of the blade of the beam energy modulator where the thickness is small compared to the extraction intensity of the ion beam passing through a flat section of the blade of the beam energy modulator where the thickness is great.

24. A charged particle beam irradiation system comprising:

an ion source for generating a charged particle beam;

a synchrotron for accelerating the charged particle beam extracted from the ion source, the synchrotron including a radio frequency applying device for beam extraction;

a beam irradiation apparatus having a beam energy modulator and arranged for irradiating an object with the charged particle beam extracted from said synchrotron and having passed said beam energy modulator, the beam energy modulator being rotated and the thickness thereof in the axial direction differing in the rotational direction, the beam energy modulator being used to control a width of a spread-out Bragg peak (SOBP); and

a controller for controlling the extraction intensity of the charged particle beam extracted from the synchrotron by controlling an amplitude of a radio frequency signal supplied to the a radio frequency applying device on the basis of the rotational angle of the beam energy modulator, the extraction intensity being controlled while the charged particle beam is being extracted from the synchrotron before reaching the beam irradiation apparatus.

26. A charged particle beam irradiation system comprising:

a synchrotron for accelerating a charged particle beam, the synchrotron including a radio frequency applying device for beam extraction;

a beam irradiation apparatus having a beam energy modulator and arranged for irradiating an object with the charged particle beam extracted from said synchrotron and having passed said beam energy modulator, the beam energy modulator being rotated and the thickness thereof in the axial direction differing in the rotational direction, the beam energy modulator being used to control a width of a spread-out Bragg peak (SOBP); and

a controller for controlling the amplitude of a radio frequency signal supplied to the radio frequency applying device on the basis of the rotational angle of the beam energy modulator, the amplitude being controlled while the charged particle beam is being extracted from the synchrotron before reaching the beam irradiation apparatus.

27. The charged particle beam irradiation system according to claim 26, further comprising:

an angle detector for detecting the rotational angle of the beam energy modulator,

wherein the controller controls the amplitude of the radio frequency signal on the basis of the rotational angle detected by the angle detector.

30. A charged particle beam irradiation system comprising:

a synchrotron for accelerating a charged particle beam, the synchrotron including a radio frequency applying device for beam extraction;

a beam irradiation apparatus having a beam energy modulator and arranged for irradiating an object with the charged particle beam extracted from said synchrotron and having passed said beam energy modulator, the beam energy modulator being rotated and the thickness thereof in the axial direction differing in the rotational direction, the beam energy modulator being used to control a width of a spread-out Bragg peak (SOBP); and

a controller for controlling the extraction intensity of the charged particle beam extracted from the synchrotron by controlling an amplitude of a radio frequency signal supplied to the radio frequency applying device on the basis of the thickness of the beam energy modulator in the axial direction, the extraction intensity being controlled while the charged particle beam is being extracted from the synchrotron before reaching the beam irradiation apparatus.

32. The charged particle beam irradiation system according to claim 30, wherein the thickness of the beam energy modulator is determined on the basis of the rotational angle of the beam energy modulator.

31. A charged particle beam irradiation system comprising:

a synchrotron for accelerating a charged particle beam, the synchrotron including a radio frequency applying device for beam extraction;

a beam irradiation apparatus having a beam energy modulator and arranged for irradiating an object with the charged particle beam extracted from said synchrotron and having passed said beam energy modulator, the beam energy modulator being rotated and the thickness thereof in the axial direction differing in the rotational direction, the beam energy modulator being used to control a width of a spread-out Bragg peak (SOBP); and

a controller for controlling the amplitude of a radio frequency signal supplied to the radio frequency applying device on the basis of the thickness of the beam energy modulator in the axial direction, the amplitude being controlled while the charged particle beam is being extracted from the synchrotron before reaching the beam irradiation apparatus.

33. A charged particle beam irradiation system comprising:

a synchrotron for accelerating a charged particle beam, the synchrotron including a radio frequency applying device for beam extraction;

a beam irradiation apparatus having a beam energy modulator and arranged for irradiating an object with the charged particle beam extracted from said synchrotron and having passed said beam energy modulator, the beam energy modulator being rotated and the thickness thereof in the axial direction differing in the rotational direction, the beam energy modulator being used to control a width of a spread-out Bragg peak (SOBP); and

a controller for controlling the extraction intensity of the charged particle beam extracted from the synchrotron while the charged particle beam is being extracted from the synchrotron before reaching the beam irradiation apparatus, by controlling an amplitude of a radio frequency signal supplied to the radio frequency applying device when an ion beam having energy different from the energy to which the shape of the beam energy modulator is optimized is incident on the beam energy modulator.

35. A charged particle beam irradiation system comprising:

a synchrotron for accelerating a charged particle beam, the synchrotron including a radio frequency applying device for beam extraction;

a beam irradiation apparatus having a beam energy modulator and arranged for irradiating an object with the charged particle beam extracted from said synchrotron and having passed said beam energy modulator, the beam energy modulator being rotated and the thickness thereof in the axial direction differing in the rotational direction; and

by controlling an amplitude of a signal supplied to the accelerator an extraction start signal and an extraction stop signal for starting and stopping the extraction of a charged particle beam orbiting the synchrotron and a control signal for controlling the extraction intensity of the charged particle beam extracted from the synchrotron before reaching the beam irradiation apparatus by controlling an amplitude of a radio frequency signal supplied to the radio frequency applying device on the basis of the rotational angle of the beam energy modulator.

38. A method of extracting a charged particle beam, comprising the steps of:

accelerating a charged particle beam with a synchrotron, the synchrotron including a radio frequency applying device for beam extraction;

transmitting the charged particle beam extracted from the synchrotron to pass a rotating beam energy modulator, the thickness of the beam energy modulator in the axial direction differing in the rotational direction, the beam energy modulator being used to control a width of a spread-out Bragg peak (SOBP); and

controlling the extraction intensity of the charged particle beam extracted from the synchrotron by controlling an amplitude of a radio frequency signal supplied to the radio frequency applying device on the basis of the rotational angle of the beam energy modulator, the extraction intensity being controlled while the charged particle beam is being extracted from the synchrotron before reaching the beam energy modulator.

41. The method of extracting a charged particle beam according to claim 38, wherein the charged particle beam is extracted from the synchrotron on the basis of extraction intensity set values of charged particle beams corresponding to a plurality of rotational angles of the beam energy modulator.

42. The method of extracting a charged particle beam according to claim 38, wherein the extraction intensity of the charged particle beam extracted from the synchrotron is controlled by starting and stopping beam extraction.

39. A method of extracting a charged particle beam, comprising the steps of:

accelerating a charged particle beam with a synchrotron, the synchrotron including a radio frequency applying device for beam extraction;

transmitting the charged particle beam extracted from the synchrotron to pass a rotating beam energy modulator, the thickness of the beam energy modulator in the axial direction differing in the rotational direction, the beam energy modulator being used to control a width of a spread-out Bragg peak (SOBP); and

controlling the extraction intensity of the charged particle beam extracted from the synchrotron by controlling an amplitude of a radio frequency signal supplied to the radio frequency applying device on the basis of the rotating time of the beam energy modulator, the extraction intensity being controlled while the charged particle beam is being extracted from the synchrotron before reaching the beam irradiation apparatus.

40. A method of extracting a charged particle beam, comprising the steps of:

accelerating a charged particle beam with a synchrotron;

modulating the amplitude of a radio frequency signal applied to a charged particle beam on the basis of the rotational angle of a beam energy modulator while the charged particle beam is being extracted from the synchrotron before reaching the beam irradiation apparatus;

applying the modulated radio frequency signal for extracting the charged particle beam from the synchrotron; and

transmitting the extracted charged particle beam to pass a rotating beam energy modulator, the thickness of the beam energy modulator in the axial direction differing in the rotational direction, the beam energy modulator being used to control a width of a spread-out Bragg peak (SOBP).