Device and method for gradually controlling breathing
First Claim
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1. A method of manipulating breathing comprising:
- providing a stimulator programmed with an electrical stimulation protocol directed to improving ventilatory stability of a patient;
sensing respiration via a sensor and identifying one or more portions of one or more respiratory cycles including first, second and subsequent intrinsic respiratory cycles by the patient detected internally within the patient'"'"'s body;
determining via a processor in communication with the sensor when the sensed respiration is a disordered event;
when the disordered event is detected, applying electrical stimulation during a first selected intrinsic inspiration cycle at a first delay from an onset of the first intrinsic inspiration cycle;
further applying the electrical stimulation during a second intrinsic inspiration cycle at a second delay from an onset of the second intrinsic cycle; and
,further applying the electrical stimulation during one or more subsequent intrinsic breaths such that each stimulation is applied with a delay from an onset of each subsequent intrinsic breath such that the delay in each subsequent breath reduces from a previous delay until the stimulation is synchronous with a start of each subsequent intrinsic inspirationwherein the electrical stimulation is provided to tissue associated with the diaphragm of the patient at least in part during the intrinsic inspiration cycle in accordance with the electrical stimulation protocol until the sensed respiration has reached a normalized respiration such that ventilatory stability is improved.
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Abstract
A device and method is provided for controlling breathing of a subject by electrically stimulating tissue associated with the diaphragm or phrenic nerve of the subject.
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Citations
16 Claims
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1. A method of manipulating breathing comprising:
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providing a stimulator programmed with an electrical stimulation protocol directed to improving ventilatory stability of a patient; sensing respiration via a sensor and identifying one or more portions of one or more respiratory cycles including first, second and subsequent intrinsic respiratory cycles by the patient detected internally within the patient'"'"'s body; determining via a processor in communication with the sensor when the sensed respiration is a disordered event; when the disordered event is detected, applying electrical stimulation during a first selected intrinsic inspiration cycle at a first delay from an onset of the first intrinsic inspiration cycle; further applying the electrical stimulation during a second intrinsic inspiration cycle at a second delay from an onset of the second intrinsic cycle; and
,further applying the electrical stimulation during one or more subsequent intrinsic breaths such that each stimulation is applied with a delay from an onset of each subsequent intrinsic breath such that the delay in each subsequent breath reduces from a previous delay until the stimulation is synchronous with a start of each subsequent intrinsic inspiration wherein the electrical stimulation is provided to tissue associated with the diaphragm of the patient at least in part during the intrinsic inspiration cycle in accordance with the electrical stimulation protocol until the sensed respiration has reached a normalized respiration such that ventilatory stability is improved. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A breathing stabilizer device for manipulating breathing comprising:
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an electrical stimulator programmed with an electrical stimulation protocol directed to controlling breathing of a patient; an electrode configured to be implanted to stimulate tissue associated with a phrenic nerve or diaphragm of a patient to cause a diaphragm response, wherein the stimulator is in electrical communication with the electrode to thereby supply an electrically stimulating signal to the tissue according to the electrical stimulation protocol; an intrinsic breathing detector configured to detect an intrinsic breath and to identify one or more portions of one or more respiratory cycles including an onset of a first, second and subsequent intrinsic breath internally within a patient'"'"'s body; and a stimulation timer programmed to cause stimulation to occur during a respiratory cycle and to further stimulate breathing at a first respiratory rate greater than or equal to an intrinsic respiratory rate, wherein the stimulation timer is further programmed to initiate the stimulation upon detection of a respiratory disorder, where the stimulation is applied during a first selected intrinsic breath at a first delay from an onset of the first intrinsic breath, and where the stimulation is applied during a second intrinsic breath at a second delay from an onset of the second intrinsic breath such that the second delay is shorter than the first delay, and wherein the stimulation is further applied during one or more subsequent intrinsic breaths with each stimulation being applied at a delay from an onset of each subsequent intrinsic breath such that the delay in each subsequent intrinsic breath is shorter than a previous delay until the stimulation applied is synchronous with an onset of each subsequent intrinsic breath. - View Dependent Claims (9, 10, 11, 12, 13, 14, 15, 16)
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Specification