Method of neurostimulation of distinct neural structures using single paddle lead to treat multiple pain locations and multi-column, multi-row paddle lead for such neurostimulation

• US 7,979,133 B2
• Filed: 10/13/2009
• Issued: 07/12/2011
• Est. Priority Date: 01/26/2006
• Status: Active Grant

• Current Assignee: Advanced Neuromodulation Systems Incorporated (Abbott Laboratories)
• Original Assignee: Advanced Neuromodulation Systems Incorporated (Abbott Laboratories)
• Inventors: Erickson, John H., Feler, Claudio A.
• Primary Examiner(s): KAHELIN, MICHAEL WILLIAM
• Application Number:
  US12/578,396
• Publication Number:
  US 20100030300A1
• Time in Patent Office: 637 Days
• Field of Search: 607/46, 607/117
• US Class Current: 607/46
• CPC Class Codes: A61N 1/0553 Paddle shaped electrodes, e.g. for laminotomy
• CPC Class Codes: A61N 1/36071 Pain
• CPC Class Codes: A61N 1/36185 Selection of the electrode configuration

Abstract

In some embodiments, a paddle lead is implanted within a patient such that the electrodes are positioned within the cervical or thoracic spinal levels. An electrode combination on a first row of electrodes can be determined that is effective for a first pain location with minimal effects on other regions of the body. The first pain location can be addressed by stimulating a first dorsal column fiber due to the relatively fine electrical field resolution achievable by the multiple columns. Then, another electrode combination on a second row of electrodes can be determined for a second pain location with minimal effects on other regions. The second pain location could be addressed by stimulating a second dorsal column fiber. After the determination of the appropriate electrodes for stimulation, the patient'"'"'s IPG can be programmed to deliver pulses using the first and second rows according to the determined electrode combinations.

Claims

1. A system for treating chronic pain in a patient using spinal cord stimulation, wherein (i) the chronic pain includes a first pain component within a first bodily sub-region of the trunk of the patient, (ii) the chronic pain includes a second pain component within a second bodily sub-region of the lower extremities of the patient separated from the first bodily sub-region by intervening bodily sub-regions, the system comprising:

a paddle structure adapted to be implanted within the epidural space of the patient with at least 10 electrodes disposed in at least five mutually adjacent columns and at least two adjacent rows on the paddle structure;

a pulse generator that is electrically coupled to the paddle structure and that is programmable to deliver pulses to the spinal cord of the patient using the electrodes of the paddle structure

a non-transient computer-readable medium with instructions stored thereon that, when executed, cause the pulse generator to;

(i) generate a first electrical field, created by stimulation pulses having a first set of stimulation parameters including one or more first active electrode to treat chronic pain in the first bodily sub-region, the first set of stimulation parameters applied through the first active electrode, has a restricted spatial resolution to stimulate a first set of one or more dorsal column fibers; and

(ii) generate a second electrical field, created by stimulation pulses having a second set of stimulation parameters including one or more second active electrode to treat chronic pain in the second bodily sub-region, the second set of stimulation parameters applied through the second active electrode, has a restricted spatial resolution to stimulate a second set of one or more dorsal column fibers;

wherein, in response to the program, the patient experiences paresthesia in the first and second bodily sub-regions and the patient experiences minimal sensory effects from the applied electrical pulses in the intervening bodily sub-regions.

2. The system of claim 1 further comprising a programmer device capable of programming the pulse generator.

3. The system of claim 2 wherein the programmer device is adapted to initially configure the first set of stimulation parameters and the second set of stimulation parameters.

4. The system of claim 1 wherein the first set of one or more dorsal column fibers are associated with a first fasciculus of the dorsal column of the patient and the electrical field created by the stimulation pulses restricts the stimulation to the first set of dorsal column fibers associated with the first fasciculus while minimizing stimulation to adjacent dorsal column fibers in the first fasciculus or adjacent dorsal column fibers in another immediately adjacent fasciculus.

5. The system of claim 1 wherein the second set of one or more dorsal column fibers are associated with a second fasciculus of the dorsal column of the patient and the electrical field created by the stimulation pulses restricts the stimulation to the second set of dorsal column fibers associated with the second fasciculus while minimizing stimulation to adjacent dorsal column fibers in the second fasciculus or adjacent dorsal column fibers in another immediately adjacent fasciculus.

6. The system of claim 1 wherein the paddle structure is configured to spans the dorsal column of the patient'"'"'s spinal cord.

7. A system for treating pain in a patient using spinal cord stimulation, wherein (i) the pain includes a first pain location within a first bodily sub-region of the patient, (ii) the pain includes a second pain location within a second bodily sub-region of the patient separated from the first bodily sub-region by intervening bodily sub-regions, the system comprising:

a paddle structure adapted to be implanted within the epidural space of the patient with at least 10 electrodes disposed in at least five mutually adjacent columns and at least two adjacent rows on the paddle structure;

a pulse generator that is electrically coupled to the paddle structure and that is programmable to deliver pulses to the spinal cord of the patient using the electrodes of the paddle structure, wherein the pulse generator is programmed to;

(i) generate a first electrical field, created by stimulation pulses having a first set of stimulation parameters including one or more first active electrode to treat pain in the first bodily sub-region, the first set of stimulation parameters applied through the first active electrode, has a restricted spatial resolution to stimulate a first set of one or more dorsal column fibers;

(ii) generate a second electrical field, created by stimulation pulses having a second set of stimulation parameters including one or more second active electrode to treat pain in the second bodily sub-region, the second set of stimulation parameters applied through the second active electrode, has a restricted spatial resolution to stimulate a second set of one or more dorsal column fibers;

wherein, in response to the applied electrical pulses, the patient experiences paresthesia in the first and second bodily sub-regions and the patient experiences minimal sensory effects from the applied electrical pulses in the intervening bodily sub-regions.

8. The method of claim 7 wherein the paddle structure is adapted to be implanted in a lower thoracic vertebral level selected from the group consisting of T8, T9, T10, T11 and T12.

9. The method of claim 7 wherein the paddle structure is configured to spans the physiological midline of the patient.

10. The method of claim 7 wherein the paddle structure is adapted to be implanted in a cervical vertebral level selected from the group consisting of C1, C2, C3, C4, C5, C6, and C7.

11. The method of claim 7 wherein the paddle structure is adapted to be implanted in a high cervical vertebral level comprising C1, C2 or a combination thereof.

12. A system for treating pain in a patient using spinal cord stimulation, wherein (i) the pain includes a first pain location within a first bodily sub-region of the patient, (ii) the pain includes a second pain location within a second bodily sub-region of the patient separated from the first bodily sub-region by intervening bodily sub-regions, the system comprising:

a paddle structure adapted to be implanted within the epidural space of the patient with at least 10 electrodes disposed in at least five mutually adjacent columns and at least two adjacent rows on the paddle structure;

a pulse generator that is electrically coupled to the paddle structure to deliver pulses to the spinal cord of the patient using the electrodes of the paddle structure;

a programming device that is capable of communicating with the pulse generator;

wherein the pulse generator is programmed to apply electrical pulses to the patient through the stimulation lead to generate;

(i) a first electrical field, created by stimulation pulses having a first set of stimulation parameters including one or more first active electrode to treat pain in the first bodily sub-region, the first set of stimulation parameters applied through the first active electrode, has a restricted spatial resolution to stimulate a first set of one or more dorsal column fibers;

(ii) a second electrical field, created by stimulation pulses having a second set of stimulation parameters including one or more second active electrode to treat pain in the second bodily sub-region, the second set of stimulation parameters applied through the second active electrode, has a restricted spatial resolution to stimulate a second set of one or more dorsal column fibers;

wherein, in response to the applied electrical pulses, the patient experiences paresthesia in the first and second bodily sub-regions and the patient experiences minimal sensory effects from the applied electrical pulses in the intervening bodily sub-regions.

13. The method of claim 12 wherein the first set of stimulation parameters and the second set of stimulation parameters are determined by the programming device and communicated to the pulse generator.