Methods and devices for automated biopsy and collection of soft tissue

• US 7,981,050 B2
• Filed: 02/06/2007
• Issued: 07/19/2011
• Est. Priority Date: 03/24/1994
• Status: Expired due to Fees

• Current Assignee: Devicor Medical Products Incorporated (Danaher Corporation)
• Original Assignee: Devicor Medical Products Incorporated (Danaher Corporation)
• Inventors: Burbank, Fred H., Stuart, J. Michael, Galt, Kenneth M., Ritchart, Mark A.
• Primary Examiner(s): Hindenburg; Max
• Assistant Examiner(s): Foreman; Jonathan M
• Application Number:
  US11/671,500
• Publication Number:
  US 20070156064A1
• Time in Patent Office: 1,624 Days
• Field of Search: 600562-568, 606/167, 606/170
• US Class Current: 600/566
• CPC Class Codes: A61B 10/0266 means for severing sample
• CPC Class Codes: A61B 10/0275 with sample notch, e.g. on the side of inner stylet
• CPC Class Codes: A61B 10/0283 with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe A61B10/025, A61B10/0266 take precedence
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2010/0208 Biopsy devices with actuators, e.g. with triggered spring mechanisms
• CPC Class Codes: A61B 2010/0225 for taking multiple samples
• CPC Class Codes: A61B 2017/303 with four or more legs
• CPC Class Codes: A61B 6/12 Arrangements for detecting or locating foreign bodies
• CPC Class Codes: A61B 8/0841 for locating instruments

Abstract

Instruments for performing percutaneous biopsy procedures are disclosed, which have advantageous features for improving functionality and performance over prior art devices. These instruments comprise two types, single-use devices, and multiple-use devices having active tissue capture capability. Improved features include the ability to retrieve and evaluate multiple tissue samples during a single insertion procedure, without physical handling of the samples, as well as constructional features, such as a molded tissue cassette housing, variant vacuum port embodiments suited for different tissue environments, and a method for backflushing the instrument to remove biological debris, among others.

Claims

1. A biopsy device comprising:

an outer hollow cannula having a closed tissue piercing distal tip and a lateral tissue receiving port disposed proximally of the distal tip;

a hollow inner cutting member having a sharpened distal end for severing tissue received in the lateral tissue receiving port of the outer hollow cannula; and

a rotatably driven tissue sample holder disposed proximally of the lateral tissue receiving port, wherein the rotatably driven tissue sample holder comprises a plurality of tissue sample chambers, wherein each tissue sample chamber of the plurality of tissue sample chambers is adapted to receive at least one tissue sample severed by the hollow inner cutting member;

wherein the rotatably driven tissue sample holder is rotatable about an axis offset from a longitudinal axis of the hollow inner cutting member;

wherein the rotatably driven tissue sample holder is positioned and configured to rotate relative to the hollow inner cutting member to successively align the tissue sample chambers with the longitudinal axis of the hollow inner cutting member.

2. The biopsy device of claim 1 wherein the rotatably driven tissue sample holder is adapted to receive multiple tissue samples.

3. The biopsy device of claim 1 wherein rotatably driven tissue sample holder is rotatably driven by a drive motor.

4. The biopsy device of claim 3 wherein the rotatably driven tissue sample holder is belt driven by the drive motor.

5. The biopsy device of claim 1 wherein the rotatably driven tissue sample holder comprises a belt driven rotary tissue cassette.

6. A biopsy device comprising:

an outer hollow cannula having a closed tissue piercing distal tip and a lateral tissue receiving port disposed proximally of the distal tip;

a hollow inner cutting member having a sharpened distal end for severing tissue received in the lateral tissue receiving port of the outer hollow cannula, wherein the hollow inner cutting member is rotatable and translatable with respect to the lateral tissue receiving port to sever tissue received in the tissue receiving port; and

a rotatably driven tissue sample holder disposed proximally of the lateral tissue receiving port, wherein the rotatably driven tissue sample holder comprises a plurality of tissue sample chambers, wherein each tissue sample chamber of the plurality of tissue sample chambers is adapted to receive at least one tissue sample severed by the hollow inner cutting member;

wherein the rotatably driven tissue sample holder is adapted and positioned to rotate about an axis offset from and generally parallel to the longitudinal axis of the hollow inner cutting member;

wherein the rotatably driven tissue sample holder is positioned and configured to rotate relative to the hollow inner cutting member to successively align the tissue sample chambers with the longitudinal axis of the hollow inner cutting member.

7. A biopsy device comprising:

an outer hollow cannula having a closed distal tip and a lateral tissue receiving port disposed proximally of the distal tip;

a hollow inner cutting member having a sharpened distal end for severing tissue received in the lateral tissue receiving port of the outer hollow cannula; and

a rotatably driven tissue sample holder disposed proximally of the lateral tissue receiving port, wherein the rotatably driven tissue sample holder comprises a plurality of discrete tissue sample receiving portions, wherein the rotatably driven tissue sample holder is configured to receive tissue samples in severed by the hollow inner cutting member in discrete spaced apart positions in the plurality of discrete tissue sample receiving portions;

wherein the rotatably driven tissue sample holder is rotatable about an axis offset from a longitudinal axis of the hollow inner cutting member;

wherein the rotatably driven tissue sample holder is positioned and configured to rotate relative to the hollow inner cutting member to successively index the discrete tissue sample receiving portions relative to the longitudinal axis of the hollow inner cutting member.

8. The biopsy device of claim 7, wherein the distal tip is configured to pierce tissue.

9. The biopsy device of claim 7, wherein the plurality of tissue sample receiving portions comprise a plurality of tissue sample chambers.

10. The biopsy device of claim 9, wherein the rotatably driven tissue sample holder comprises a rotatable cylindraceous member, wherein the tissue sample chambers comprise elongate passages formed in the rotatable cylindraceous member.