Lead electrode incorporating extracellular matrix
First Claim
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1. A method comprising affixing an isolated extracellular matrix (ECM) sheet including isolated ECM having a native three dimensional microstructure to an electrode in an amount effective to inhibit fibrotic capsule formation and/or enhance excitable tissue formation around a lead comprising the electrode after implantation of the lead.
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Abstract
Implantable devices containing extracellular matrix and methods of using the devices are provided.
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17 Claims
- 1. A method comprising affixing an isolated extracellular matrix (ECM) sheet including isolated ECM having a native three dimensional microstructure to an electrode in an amount effective to inhibit fibrotic capsule formation and/or enhance excitable tissue formation around a lead comprising the electrode after implantation of the lead.
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