Injection device with secondary reservoir

• US 7,981,081 B2
• Filed: 10/30/2009
• Issued: 07/19/2011
• Est. Priority Date: 04/11/2005
• Status: Active Grant

• Current Assignee: Embecta Corporation
• Original Assignee: Becton, Dickinson & Co
• Inventors: Marsh, Ronald W., Browka, Edward P., Follman, Mark
• Primary Examiner(s): Lucchesi; Nicholas D
• Assistant Examiner(s): HOLLOWAY, IAN KNOBEL
• Application Number:
  US12/588,853
• Publication Number:
  US 20100049140A1
• Time in Patent Office: 627 Days
• Field of Search: 604 68- 69, 604 82- 83, 604/506
• US Class Current: 604/117
• CPC Class Codes: A61M 2005/3128 Incorporating one-way valves, e.g. pressure-relief or non-return valves
• CPC Class Codes: A61M 5/204 connected to external reservoirs for multiple refilling
• CPC Class Codes: A61M 5/283 by telescoping of ampoules or carpules with the syringe body
• CPC Class Codes: A61M 5/3155 by rotational movement of dose setting member, e.g. during setting or filling of a syringe
• CPC Class Codes: A61M 5/31561 using freely adjustable volume steps
• CPC Class Codes: A61M 5/3158 performed by axially moving actuator operated by user, e.g. an injection button
• CPC Class Codes: A61M 5/46 having means for controlling depth of insertion

Abstract

A method and apparatus for injecting fluid into areas having high density tissue that creates a high backpressure resistance on the injection device is disclosed. The high backpressure resistance is overcome through a mechanical advantage achieved by using a secondary reservoir having a cross-sectional area smaller than the cross-sectional area of a primary reservoir. Exemplary injection device reservoir housings may comprise a primary reservoir, a secondary reservoir, a check valve, a septum penetrating cannula, travel limits, a pen needle connecting portion, sliding seal guide ribs, a sliding seal, a pen needle assembly, a needle stop, and a patient needle.

Claims

1. An injection mechanism for injecting fluid into a targeted tissue layer comprising:

a primary reservoir for storing fluid prior to injection and filling a secondary reservoir with a dosage amount of fluid to be injected;

a secondary reservoir for receiving and holding the dosage amount of fluid to be injected from the first reservoir, wherein the secondary reservoir is in series with the primary reservoir and has a smaller cross-sectional area than the cross-sectional area of the primary reservoir; and

a needle connecting portion comprising a sliding seal, a needle assembly, and a needle stop, wherein the sliding seal comprises a needle septum disposed at least partially within the secondary reservoir and having a cross-sectional area smaller than the cross-sectional area of the primary reservoir; and

a patient needle disposed at least partially within the needle septum of the sliding seal, and for penetrating the skin of the patient to inject the dosage amount of fluid of the secondary reservoir in the targeted tissue layer during injection, wherein said patient needle has an exposed length of between approximately 0.5 mm and approximately 5 mm.

2. The injection mechanism of claim 1, wherein said patient needle has an exposed length of between approximately 0.5 mm and approximately 3.5 mm.

3. The injection mechanism of claim 1, wherein said patient needle has an exposed length of between approximately 1.5 mm and approximately 3.0 mm.

4. The injection mechanism of claim 1, wherein said patient needle delivers fluid in the intradermal or the shallow subcutaneous tissue space.

5. The injection mechanism of claim 1, further comprising:

a check valve located between the primary and secondary reservoirs for preventing fluid from leaking from the secondary reservoir back into the primary reservoir or medicament cartridge.

6. The injection mechanism of claim 1, wherein the fluid is at least one of a therapeutic drug, vaccine or diagnostic material.

7. The injection mechanism of claim 1, wherein the primary reservoir is adapted to receive a medicament cartridge for administering said dosage of medication.

8. The injection mechanism of claim 7, wherein a dose means is used to transfer said dosage of medication into said secondary reservoir in preparation for giving an injection.

9. The injection mechanism of claim 1, wherein said secondary reservoir is filled with fluid causing said sliding seal to move proximal in said secondary reservoir.

10. The injection mechanism of claim 1, wherein the patient needle penetrates said patient skin until stopped by the needle stop, wherein said needle stop has an area larger than that of said patient needle.

11. The injection mechanism of claim 10, wherein an injection is administered by applying pressure to said primary reservoir thereby causing said fluid in said secondary reservoir to flow through said needle septum and patient needle to be injected into said intradermal tissue.

12. An injection mechanism for injecting fluid into a targeted tissue layer comprising:

a primary reservoir for storing fluid prior to injection and filling a secondary reservoir with a dosage amount of fluid to be injected;

a secondary reservoir for receiving and holding the dosage amount of fluid to be injected from the first reservoir, wherein the secondary reservoir is in series with the primary reservoir and has a smaller cross-sectional area than the cross-sectional area of the primary reservoir;

a needle connecting portion comprising a sliding seal, a needle assembly, and a needle stop, wherein the sliding seal comprises a needle septum disposed at least partially within the secondary reservoir and having a cross-sectional area smaller than the cross-sectional area of the primary reservoir; and

a patient needle disposed at least partially within the needle septum of the sliding seal, and for penetrating the skin of the patient to inject the dosage amount of fluid of the secondary reservoir in the targeted tissue layer during injection; and

a check valve located between the primary and secondary reservoirs for preventing fluid from leaking from the secondary reservoir back into the primary reservoir or medicament cartridge.

13. The injection mechanism of claim 12, wherein said patient needle has an exposed length of between approximately 0.5 mm and approximately 5 mm.

14. The injection mechanism of claim 12, wherein said patient needle delivers fluid in the intradermal or the shallow subcutaneous tissue space.

15. The injection mechanism of claim 12, wherein the fluid is at least one of a therapeutic drug, vaccine or diagnostic material.

16. The injection mechanism of claim 12, wherein the primary reservoir is adapted to receive a medicament cartridge for administering said dosage of medication.

17. The injection mechanism of claim 16, wherein a dose means is used to transfer said dosage of medication into said secondary reservoir in preparation for giving an injection.

18. The injection mechanism of claim 12, wherein said secondary reservoir is filled with fluid causing said sliding seal to move proximal in said secondary reservoir.

19. The injection mechanism of claim 12, wherein the patient needle penetrates said patient skin until stopped by the needle stop, wherein said needle stop has an area larger than that of said patient needle.

20. The injection mechanism of claim 19, wherein an injection is administered by applying pressure to said primary reservoir thereby causing said fluid in said secondary reservoir to flow through said needle septum and patient needle to be injected into said intradermal tissue.