Dialysis system having regimen generation methodology

• US 7,981,281 B2
• Filed: 07/09/2008
• Issued: 07/19/2011
• Est. Priority Date: 07/09/2008
• Status: Active Grant

• Current Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Original Assignee: Baxter Healthcare SA (Baxter International Inc.), Baxter International Inc.
• Inventors: Yu, Anping, Cizman, Borut, Vonesh, Edward F., Childers, Robert W.
• Primary Examiner(s): Drodge; Joseph W
• Application Number:
  US12/170,184
• Publication Number:
  US 20100010424A1
• Time in Patent Office: 1,105 Days
• Field of Search: 210/96.1, 210/96.2, 210/141, 210/143, 210/321.65, 210645-647, 604/29, 604/65, 604/67, 600/300, 702/19, 705/2, 705/3, 706 45- 48, 706/61, 706/924, 700 28- 33, 700/273
• US Class Current: 210/143
• CPC Class Codes: A61M 1/1522 the interface being evacuated interfaces to enhance contact
• CPC Class Codes: A61M 1/155 with treatment-fluid pumping means or components thereof
• CPC Class Codes: A61M 1/1565 Details of valves
• CPC Class Codes: A61M 1/159 specially adapted for peritoneal dialysis
• CPC Class Codes: A61M 1/28 Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
• CPC Class Codes: A61M 1/281 Instillation other than by gravity
• CPC Class Codes: A61M 1/282 Operational modes
• CPC Class Codes: A61M 1/287 Dialysates therefor
• CPC Class Codes: A61M 2205/502 User interfaces, e.g. screens or keyboards
• CPC Class Codes: G16H 10/60 for patient-specific data, e.g. for electronic patient records
• CPC Class Codes: G16H 20/40 relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
• CPC Class Codes: G16H 40/60 for the operation of medical equipment or devices
• CPC Class Codes: G16H 50/50 for simulation or modelling of medical disorders
• CPC Class Codes: Y10S 706/924 Medical

Abstract

A peritoneal dialysis system includes a logic implementer configured to: (i) accept at least one therapy target input; (ii) accept at least one patient transport characteristic input; (iii) accept at least one solution input; (iv) accept at least one fluid volume input; (v) accept at least one therapy time input, at least one of the inputs (ii) to (v) including an input range; and (vi) generate each therapy regimen using the inputs of (ii), (iii), (iv) and (v), including each of the possibilities within the at least one input range, that satisfy the at least one therapy target input.

Claims

1. A peritoneal dialysis (“

PD”

) system comprising;

equipment configured to perform at least one of ultrafiltration or dialysis of patient fluid; and

a logic implementer configured to;

(i) accept at least one therapy target input;

(ii) accept at least one patient transport characteristic input;

(iii) accept at least one solution input;

(iv) accept at least one fluid volume input;

(v) accept at least one therapy time input, at least one of the inputs of (iii), (iv) and (v) including a plurality of possible values; and

(vi) generate a plurality of therapy regimens for the equipment using the inputs of (ii), (iii), (iv) and (v), including the plurality of possible values, that satisfy the at least one therapy target input.

2. The peritoneal dialysis system of claim 1, wherein the equipment includes an automatic peritoneal dialysis (“

APD”

) machine operable to run a PD therapy according to a selected one of the therapy regimens.

3. The peritoneal dialysis system of claim 1, the logic implementer located at a location remote from the equipment.

4. The peritoneal dialysis system of claim 1, wherein the plurality of possible values include an input range/threshold.

5. The peritoneal dialysis system of claim 4, the logic implementer configured to generate each possible therapy regimen that satisfies the at least one therapy target input of (i) using each of the possible values of the input range/threshold.

6. The peritoneal dialysis system of claim 4, which includes a target therapy input range/threshold, the target therapy input range/threshold including at least one of:

(a) a minimum urea clearance;

(b) a minimum urea Kt/V;

(c) a minimum creatinine clearance;

(d) a maximum glucose absorption; and

(f) a minimum ultrafiltration removal amount.

7. The peritoneal dialysis system of claim 4, which includes a solution input range/threshold, the solution input range threshold including a plurality of percentage dextrose settings for the solution.

8. The peritoneal dialysis system of claim 7, the solution input range/threshold including the plurality of percentage dextrose settings for at least one of:

(a) a night fill, (b) a last night fill and (c) a day fill.

9. The peritoneal dialysis system of claim 4, which includes a fluid volume range/threshold, the fluid volume range/threshold including at least one of:

a total volume minimum, a total volume maximum, an individual fill volume minimum and an individual fill volume maximum.

10. The peritoneal dialysis system of claim 9, the fluid volume range/threshold applicable to at least one of:

(a) a night fill, (b) a last night fill, and (c) a day fill.

11. The peritoneal dialysis system of claim 4, which includes at least one therapy time range/threshold, the therapy time range/threshold including at least one of:

a minimum therapy time and a maximum therapy time.

12. The peritoneal dialysis system of claim 11, the at least one therapy time range/threshold applicable to at least one of (a) a night fill and (b) a day fill.

13. The peritoneal dialysis system of claim 1, the patient transport characteristic including at least one of:

(a) a mass transfer area coefficient (“

MTAC”

) for urea, (b) a MTAC for creatinine, (c) a MTAC for glucose, (d) a patient hydraulic permeability coefficient characteristic and (e) a fluid absorption characteristic.

14. The peritoneal dialysis system of claim 1, wherein the at least one solution input of (iii) includes a selection from a plurality of different solution types.

15. The peritoneal dialysis system of claim 14, the at least one solution input of (iii) entered for at least one of a last fill and a day fill.

16. A peritoneal dialysis system comprising:

equipment configured to perform at least one of ultrafiltration or dialysis of patient fluid; and

a logic implementer configured to;

(i) accept at least one therapy target input;

(ii) accept at least one patient transport characteristic input;

(iii) accept at least one solution input;

(iv) accept at least one fluid volume input;

(v) accept at least one therapy time input, at least one of the inputs (ii) to (v) including an input range; and

(vi) generate a plurality of therapy regimens for the equipment using the inputs of (ii), (iii), (iv) and (v), the plurality of therapy regimens including each possible therapy regimen that satisfies the at least one therapy target input of (i) using each value within the at least one input range.

17. The peritoneal dialysis system of claim 16, which includes a solution dextrose range for the at least one solution input of (iii), a minimum and maximum individual fill volume range for the at least one fluid volume input of (iv), and a minimum and maximum therapy time range for the at least one therapy time input of (v).

18. The peritoneal dialysis system of claim 17, which further includes a range of selectable solution types for the at least one solution input of (iii) and a minimum and maximum total fill volume for the at least one fluid volume input of (iv).

19. The peritoneal dialysis system of claim 16, wherein the at least one input range is applicable to at least two of a night fill, a night last fill, and a day fill.

20. The peritoneal dialysis system of claim 16, the logic implementer located at a location remote from the equipment.

21. A peritoneal dialysis system comprising:

equipment configured to perform at least one of ultrafiltration or dialysis of patient fluid; and

a logic implementer configured to;

(i) accept a plurality of therapy target inputs;

(ii) accept a plurality of patient transport inputs;

(iii) accept a range of solution inputs;

(iv) accept a range of fluid volume fill inputs;

(v) accept a range of fill time inputs; and

(vi) generate a plurality of therapy regimens for the equipment using the inputs of (ii) and each value within the ranges of (iii) to (v), the plurality of therapy regimens including each possible therapy regimen that satisfies the plurality of therapy target inputs of (i).

22. The peritoneal dialysis system of claim 21, wherein the therapy target inputs of (i) are therapy target thresholds.

23. The peritoneal dialysis system of claim 21, the logic implementer configured to auto-input at least one of the values from at least one of the input ranges.

24. The peritoneal dialysis system of claim 23, the logic implementer further configured to override the at least one auto-inputted possibility with a patient-selected possibility.

25. The peritoneal dialysis system of claim 21, the logic implementer located at a location remote from the equipment.