System and method for noninvasive electrocardiographic imaging (ECGI)
First Claim
Patent Images
1. A noninvasive system for determining electrical activity for a heart of a living being, the system comprising:
- memory to store computer-readable instructions; and
a processor configured to access the memory and execute the computer readable instructions to compute heart electrical activity data that represents heart electrical activity of the living being from a set of noninvasively measured body surface electrical potentials using data that describes a geometric relationship between a plurality of locations corresponding to where the body surface electrical potentials were measured and a surface representation of the heart;
wherein the processor executes the computer readable instructions to compute the heart electrical activity data by translating the measured body surface electrical potentials to surface potentials on the surface representation of the heart without using a mesh of any heart surface.
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Abstract
Noninvasive systems and methods are provided for determining electrical activity for a heart of a living being. A processor is configured to meshlessly compute data that represents heart electrical activity from a set of noninvasively measured body surface electrical potentials. This is accomplished using data that describes a geometric relationship between a plurality of locations corresponding to where the body surface electrical potentials were measured and the heart.
72 Citations
37 Claims
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1. A noninvasive system for determining electrical activity for a heart of a living being, the system comprising:
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memory to store computer-readable instructions; and a processor configured to access the memory and execute the computer readable instructions to compute heart electrical activity data that represents heart electrical activity of the living being from a set of noninvasively measured body surface electrical potentials using data that describes a geometric relationship between a plurality of locations corresponding to where the body surface electrical potentials were measured and a surface representation of the heart; wherein the processor executes the computer readable instructions to compute the heart electrical activity data by translating the measured body surface electrical potentials to surface potentials on the surface representation of the heart without using a mesh of any heart surface. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13)
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14. A method for noninvasively reconstructing electrical activity of a heart of a living being, the living being having a body surface, the method comprising:
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computing heart electrical activity data corresponding to heart electrical activity from a set of noninvasively measured body surface electrical potentials via an algorithm that translates the noninvasively measured body surface electrical potentials to the heart electrical activity data, the algorithm not using a mesh of any heart surface and not using a mesh of the body surface; and generating a display based on the heart electrical activity data. - View Dependent Claims (15, 16, 17, 18, 19)
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20. A non-transitory computer readable medium for use in connection with noninvasively computing electrical activity of a heart of a living being, the living being having a body surface, the computer readable medium comprising:
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a code segment executable by a processor for computing data corresponding to heart electrical activity from a set of noninvasively measured body surface electrical potentials via a meshless algorithm that translates the noninvasively measured body surface electrical potentials to the heart electrical activity data; a code segment executable by a processor for determining a geometry of locations on the body surface where the body surface electrical potentials were noninvasively measured; and a code segment executable by a processor for determining a geometry of an epicardial envelope of the living being; and wherein the computing code segment is configured to compute the set of epicardial envelope electrical potentials from the set of noninvasively measured body surface potentials and the determined geometries. - View Dependent Claims (21, 22, 23, 24, 25, 26)
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27. A method for reconstructing electrical potentials on a surface inside a volume, wherein the volume comprises a field that satisfies Laplace equation, the volume having an outer surface, the method comprising:
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computing data corresponding to a plurality of electrical potentials on a surface inside the volume from a set electrical potentials measured at the volume'"'"'s outer surface via a meshless algorithm that translates the measured outer surface electrical potentials to the inside surface electrical potential data without using a mesh of the surface inside the volume and without using a mesh of the outer surface of the volume; and generating a display based on the heart electrical activity data. - View Dependent Claims (28, 29, 30, 31)
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32. A system for reconstructing heart electrical activity for a heart of a living being, the living being having a torso, the torso having an outer surface, the system comprising:
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memory to store computer-readable instructions; and a processor configured to access the memory and execute the computer readable instructions to (1) receive data representing a plurality of electrical potentials measured on the torso outer surface at a plurality locations along the torso outer surface, (2) receive spatial relationship data that describes a spatial relationship between the torso outer surface and an epicardial envelope, (3) determine the torso outer surface locations where the electrical potentials were measured, (4) define a plurality of locations along the epicardial envelope, (5) define a plurality of source node locations outside the torso outer surface, (6) define a plurality of source node locations inside the epicardial envelope, (7) based at least in part upon the spatial relationship data, the determined torso outer surface locations, and the defined source node locations, compute a matrix of coefficients A that spatially relates each determined torso outer surface location to each defined source node location, (8) perform an inverse computation on A and the received electrical potential data to compute a plurality of source node location coefficients, (9) based at least in part upon the spatial relationship data, the defined epicardial envelope locations, and the defined source node locations, compute a matrix of coefficients B that relates each defined epicardial envelope location to each defined source node location, (10) perform a forward computation using B and the source node coefficients to compute electrical activity data that represents electrical activity on the epicardial envelope, and (11) store the electrical activity data in the memory. - View Dependent Claims (33, 34, 35, 36)
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37. A non-transitory computer readable medium having computer executable instructions for performing a method that comprises:
computing heart electrical activity data that represents heart electrical activity from a set of noninvasively measured body surface electrical potentials using data that describes a geometric relationship between a plurality of locations corresponding to where the body surface electrical potentials were measured and a representation of a surface of a heart of a living being, wherein the computing comprising; performing a first computation on a first transfer matrix and the noninvasively measured body surface electrical potentials to compute a first plurality of coefficients, the first computation being performed without using a mesh of any heart surface; and performing a second computation using a second transfer matrix and the first plurality of coefficients to compute a set of cardiac surface electrical potentials for the representation of the surface of the heart, the second computation being performed without using a mesh of any heart surface, the set of cardiac surface electrical potentials for the representation of the surface of the heart being stored in memory.
Specification