Gastric electrical stimulation with multi-site stimulation anti-desensitization feature
First Claim
1. A method for gastric stimulation with reduced desensitization, the method comprising:
- delivering first electrical stimulation therapy to a gastrointestinal organ of a patient via a first electrode combination positioned at a first position on the gastrointestinal organ for a first period of time greater than or equal to approximately 30 seconds; and
delivering second electrical stimulation therapy to the gastrointestinal organ via a second electrode combination positioned at a second position on the gastrointestinal organ for a second period of time greater than or equal to approximately 30 seconds,wherein the first and second electrical stimulation therapies are configured to produce a substantially identical therapeutic result, and wherein at least one electrode of the first electrode combination is displaced at least approximately three centimeters from at least one electrode of the second electrode combination.
1 Assignment
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Accused Products
Abstract
The disclosure is directed to gastric stimulation programmers, stimulators and methods for controlling delivery of gastric stimulation therapy to maintain the efficacy of the therapy over time. Maintaining the efficacy of gastric stimulation therapy may be possible by implementing one or more anti-desensitization features in a gastric stimulation controller or stimulator. As electrical stimulation therapy is continuously delivered to a patient, the stimulated tissue may become desensitized to the electrical stimulation therapy such that the beneficial effect of the electrical stimulation is diminished. Once desensitization occurs, the affected tissue may not respond favorably to electrical stimulation therapy. Application of one or more anti-desensitization features to control gastric stimulation therapy may reduce or prevent desensitization and effectively extend the efficacy of the therapy over time.
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Citations
34 Claims
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1. A method for gastric stimulation with reduced desensitization, the method comprising:
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delivering first electrical stimulation therapy to a gastrointestinal organ of a patient via a first electrode combination positioned at a first position on the gastrointestinal organ for a first period of time greater than or equal to approximately 30 seconds; and delivering second electrical stimulation therapy to the gastrointestinal organ via a second electrode combination positioned at a second position on the gastrointestinal organ for a second period of time greater than or equal to approximately 30 seconds, wherein the first and second electrical stimulation therapies are configured to produce a substantially identical therapeutic result, and wherein at least one electrode of the first electrode combination is displaced at least approximately three centimeters from at least one electrode of the second electrode combination. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12)
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13. A gastrointestinal electrical stimulation device comprising:
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a first electrode combination implantable at a first position on a gastrointestinal organ of a patient; a second electrode combination implantable at a second position on the gastrointestinal organ; and a stimulation generator that delivers first electrical stimulation therapy to the gastrointestinal organ via the first electrode combination for a first period of time greater than or equal to approximately 30 seconds, and delivers second electrical stimulation therapy to the gastrointestinal organ via a second electrode combination for a second period of time greater than or equal to approximately 30 seconds, wherein the first and second electrical stimulation therapies are configured to produce a substantially identical therapeutic result, at least one electrode of the first electrode combination is configured to be displaced upon implantation at least approximately three centimeters from at least one electrode of the second electrode combination, the at least one electrode of the first electrode combination is coupled to a first lead of the gastrointestinal electrical stimulation device, and the at least one electrode of the second electrode combination is coupled to a second lead of the gastrointestinal electrical stimulation device. - View Dependent Claims (14, 15, 16, 17, 18, 19, 20, 21, 22, 23)
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24. A gastrointestinal electrical stimulation device comprising:
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means for delivering first electrical stimulation therapy to a gastrointestinal organ of a patient via a first electrode combination positioned at a first position on the gastrointestinal organ for a first period of time greater than or equal to approximately 30 seconds; and means for delivering second electrical stimulation therapy to the gastrointestinal organ via a second electrode combination positioned at a second position on the gastrointestinal organ for a second period of time greater than or equal to approximately 30 seconds, wherein the first and second electrical stimulation therapies are configured to produce a substantially identical therapeutic result, at least one electrode of the first electrode combination is configured to be displaced upon implantation at least approximately three centimeters from at least one electrode of the second electrode combination, the at least one electrode of the first electrode combination is coupled to a first lead of the gastrointestinal electrical stimulation device and the at least one electrode of the second electrode combination is coupled to a second lead of the gastrointestinal electrical stimulation device. - View Dependent Claims (25, 26, 27, 28, 29, 30, 31, 32, 33, 34)
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Specification