After-loader devices and kits

• US 7,985,172 B2
• Filed: 04/27/2007
• Issued: 07/26/2011
• Est. Priority Date: 05/09/2006
• Status: Expired due to Fees

• Current Assignee: Eckert & Ziegler BEBIG S.A (Eckert & Ziegler AG)
• Original Assignee: Biocompatibles UK Limited (Boston Scientific Corporation)
• Inventors: Walker, Paul, Bleich, Edward, Viselli, Anthony, Lamoureux, Gary A., Johnston, Warren W.
• Primary Examiner(s): GILBERT, SAMUEL G
• Application Number:
  US11/741,652
• Publication Number:
  US 20080009660A1
• Time in Patent Office: 1,551 Days
• Field of Search: 600 1- 8
• US Class Current: 600/7
• CPC Class Codes: A61M 37/0069 Devices for implanting pellets, e.g. markers or solid medicaments for introducing of radioactive sources for interstitial radiation therapy, i.e. brachytherapy A61N5/1027
• CPC Class Codes: A61N 2005/1008 Apparatus for temporary insertion of sources, e.g. afterloaders
• CPC Class Codes: A61N 5/1007 Arrangements or means for the introduction of sources into the body

Abstract

After-loader devices, kits, and methods for using the same are provided. Such after-loader devices are useful for loading implants into hollow needles, especially after the needles are inserted into patient tissue. The after-loader devices can be pre-loaded with implants, before the after-loaders are connected to hubs of hollow needles, or loaded thereafter.

Claims

1. An after-loader device useful for loading an implant into a hollow needle after the needle is inserted into patient tissue,

the hollow needle having a inner diameter, an outer diameter, a distal end, a proximal end, and a cylindrical needle hub at the proximal end, the cylindrical needle hub having an outer diameter that is greater than the outer diameter of the needle,

the after-loader device comprising:

an elongated body having a proximal end and a distal end; and

a bore that extends axially through said body between said proximal and distal ends of said body;

wherein a main portion of said bore has a first diameter that is approximately equal to the inner diameter of the hollow needle;

wherein a distal portion of said bore has a second diameter that is larger than the outer diameter of the needle hub and configured to receive, and thereby connect to, the needle hub; and

wherein a depth of the distal portion of said bore is sufficient to enable the body to rigidly connect to the cylindrical needle hub of the hollow needle without requiring additional support.

2. The after-loader device of claim 1, further comprising:

a radiation shield configured to slide over an outer circumferential surface of a main portion of said body, to thereby cover the main portion of said body.

3. The after-loader device of claim 2, wherein said body is translucent or transparent so that a user can observe an implant loaded into said bore, when said radiation shield is at least partially removed.

4. The after-loader device of claim 2, wherein:

a distal portion of said body has an outer diameter that is greater than an outer diameter of said main portion of the body, and greater than an inner diameter of said radiation shield;

wherein said distal portion of said body provides a stop for the radiation shield, and also accommodates said distal portion of said bore.

5. The after-loader device of claim 4, further comprising:

a tapered outer circumference extending between said distal portion of said body and said main portion of said body;

wherein said tapered outer circumference provides for a friction fit between said body and said radiation shield.

6. The after-loader device of claim 1, further comprising:

a distal end plug to plug a distal opening of said bore; and

a proximal end plug to plug a proximal opening of said bore;

wherein said distal end plug and said proximal end plug, when respectively plugged into said distal and proximal openings of said bore, prevent an implant loaded in said bore from falling out of said bore.

7. The after-loader device of claim 6, wherein each said end plug includes a gripping portion and an insertion portion.

8. The after-loader device of claim 6, wherein said end plugs are made from a radiation blocking material.

9. The after-loader device of claim 1, wherein a proximal portion of said bore is funneled to assist with inserting an implant and/or a stylet into said bore.

10. The after-loader device of claim 1, further comprising a tapered nose at said distal end of said body, said tapered nose configured to fit into a hub of a second type of hollow needle.

11. The after-loader device of claim 1, further comprising an adapter for use in connecting said body of the after-loader device to a second type of hollow needle.

12. The after-loader device of claim 11, wherein said adaptor includes:

a central portion;

a distal hollow shaft; and

a proximal hollow shaft;

wherein said distal hollow shaft is for insertion into a hub of the second type of needle and into a proximal most portion of a lumen of the second type of needle; and

wherein said proximal hollow shaft is for insertion into said distal portion of said bore of said body of the after-loader device.

13. The after-loader device of claim 12, wherein said central portion of said adaptor includes inner threads for engaging threads on the hub of the second type of needle.

14. An after-loader device useful for loading an implant into a hollow needle after the needle is inserted into patient tissue, the after-loader device comprising:

an elongated body including distal portion and a main portion; and

a bore that extends axially through said body;

wherein a distal portion of said bore, which extends through said distal portion of said body, is configured to receive, and thereby connect to, a cylindrical needle hub of a hollow needle; and

wherein a depth of said distal portion of said bore is sufficient to enable said body to rigidly connect to a cylindrical needle hub of a hollow needle without requiring additional support.

15. The after-loader device of claim 14, further comprising:

a radiation shield configured to slide over an outer circumferential surface of said main portion of said body, to thereby cover said main portion of said body.

16. The after-loader device of claim 15, wherein said body is translucent or transparent so that a user can observe an implant loaded into said bore, when said radiation shield is at least partially removed.

17. The after-loader device of claim 15, wherein:

a distal portion of said body has an outer diameter that is greater than an outer diameter of said main portion of the body, and greater than an inner diameter of said radiation shield;

wherein said distal portion of said body provides a stop for the radiation shield, and also accommodates said distal portion of said bore.

18. The after-loader device of claim 17, further comprising:

a tapered outer circumference extending between said distal portion of said body and said main portion of said body;

wherein said tapered outer circumference provides for a friction fit between said body and said radiation shield.

19. The after-loader device of claim 14, further comprising:

a distal end plug to plug a distal opening of said bore; and

a proximal end plug to plug a proximal opening of said bore;

wherein said distal end plug and said proximal end plug, when respectively plugged into said distal and proximal openings of said bore, prevent an implant loaded in said bore from falling out of said bore.

20. The after-loader device of claim 14, wherein a proximal portion of said body includes a proximal portion of said bore, which is funneled to assist with inserting an implant and/or a stylet into said bore.

21. A brachytherapy kit, comprising:

a plurality of after-loader devices, each of which is useful for loading an implant into a hollow needle after the needle is inserted into patient tissue; and

a plurality of treatment members, each said member including a plurality of radioactive sources spaced apart from one another;

wherein each said member is loaded into a bore of one of said after-loader devices, and maintained in said bore by end-plugs or by friction between the member and said bore

wherein for each said after-loader device;

said elongated body includes proximal portion and a main portion; and

said bore extends axially through said body;

a distal portion of said bore, which extends through a distal portion of said body, is configured to receive, and thereby connect to, a cylindrical needle hub of a hollow needle; and

wherein a depth of said distal portion of said bore is sufficient to enable said body to rigidly connect to a cylindrical needle hub of a hollow needle without requiring additional support.

22. The kit of claim 21, wherein each said after-loader device includes a radiation shield that surrounds at a main portion of an elongated body of said after-loader device.

23. The kit of claim 21, further comprising:

at least one stylet having a length that is at least as long as a total length of a said after-loader device connected with a hollow needle.

24. The kit of claim 23, further comprising:

a least one hollow needle.

25. The kit of claim 21, wherein the plurality of treatment members fulfill an entire predetermined treatment plan for a patient.

26. The kit of claim 25, wherein said radiations sources in said treatment members are spaced apart from on another in accordance with the treatment plan.

27. The kit of claim 25, further comprising:

a tray holding said plurality of after-loader devices loaded with said plurality of treatment members; and

a pouch housing said tray, which is holding said plurality of after-loader devices loaded with said plurality of treatment members, wherein said pouch keeps its contents sterile until said pouch is opened.

28. A brachytherapy kit, comprising;

a plurality of after-loader devices, each of which is useful for loading an implant into a hollow needle after the needle is inserted into patient tissue; and

a plurality of treatment members, each said member including a plurality of radioactive sources spaced apart from one another;

wherein each said member is loaded into a bore of one of said after-loader devices, and maintained in said bore by end-plugs or by friction between the member and said bore; and

at least one adaptor configured to connect a said after-loader device to a second type of hollow needle.

29. The kit of claim 28, further comprising:

at least one second type of hollow needle.