Methods for determining the hair follicle inductive properties of a composition
First Claim
Patent Images
1. A method for determining hair inductive properties of a composition comprising:
- injecting a composition comprising dissociated dermal cells and epidermal cells into the deep dermis of an immunocompromised mouse, wherein the dermal cells are from a first species and epidermal cells are from a second species and wherein the first species is different from the second species; and
determining whether at least one hair follicle forms, wherein the hair follicle comprises an outer root sheath, an inner root sheath with companion layer, and dermal papilla; and
wherein formation of at least one hair follicle indicates that the composition has hair inductive properties.
1 Assignment
0 Petitions
Accused Products
Abstract
The present invention provides a method for determining hair inductive properties of a composition comprising injecting a composition comprising dissociated dermal cells and epidermal cells into skin of a mammal and determining whether at least one hair follicle forms.
134 Citations
10 Claims
-
1. A method for determining hair inductive properties of a composition comprising:
-
injecting a composition comprising dissociated dermal cells and epidermal cells into the deep dermis of an immunocompromised mouse, wherein the dermal cells are from a first species and epidermal cells are from a second species and wherein the first species is different from the second species; and determining whether at least one hair follicle forms, wherein the hair follicle comprises an outer root sheath, an inner root sheath with companion layer, and dermal papilla; and
wherein formation of at least one hair follicle indicates that the composition has hair inductive properties. - View Dependent Claims (2, 3, 4, 5, 6)
-
-
7. A method for determining hair inductive properties of a composition comprising:
-
injecting a composition comprising dissociated dermal cells and epidermal cells into the deep dermis of an immunocompromised mouse, wherein the dermal cells and epidermal cells are human; and determining whether at least one hair follicle forms, wherein the hair follicle comprises an outer root sheath, an inner root sheath with companion layer, and dermal papilla; and
wherein formation of at least one hair follicle indicates that the composition has hair inductive properties. - View Dependent Claims (8, 9, 10)
-
Specification