Automatic injection and retraction devices for use with pre-filled syringe cartridges

• US 7,988,675 B2
• Filed: 01/31/2007
• Issued: 08/02/2011
• Est. Priority Date: 12/08/2005
• Status: Active Grant

• Current Assignee: West Pharmaceutical Services of Delaware, Inc. (West Pharmaceutical Services Incorporated)
• Original Assignee: West Pharmaceutical Services of Delaware, Inc. (West Pharmaceutical Services Incorporated)
• Inventors: Crow, Doug Owen, Gillespie, Richard D. III
• Primary Examiner(s): Mendez; Manuel A
• Application Number:
  US11/669,452
• Publication Number:
  US 20070135767A1
• Time in Patent Office: 1,644 Days
• Field of Search: 604/192, 604/195, 604/197, 604/198, 604/187, 604/110, 604/263, 604/162, 604/218, 604/171, 604/181
• US Class Current: 604/181
• CPC Class Codes: A61M 2005/206 With automatic needle insertion
• CPC Class Codes: A61M 2005/2073 preventing premature release, e.g. by making use of a safety lock
• CPC Class Codes: A61M 2005/2086 having piston damping means, e.g. axially or rotationally acting retarders
• CPC Class Codes: A61M 2005/2418 comprising means for damping shocks on ampoule
• CPC Class Codes: A61M 5/2033 Spring-loaded one-shot injectors with or without automatic needle insertion multishot dosing syringes A61M5/31525, needle insertion only A61M5/3287
• CPC Class Codes: A61M 5/24 Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic ampoules or carpules A61J1/06
• CPC Class Codes: A61M 5/3204 Needle cap remover, i.e. devices to dislodge protection cover from needle or needle hub, e.g. deshielding devices
• CPC Class Codes: A61M 5/46 having means for controlling depth of insertion

Abstract

An automatic injection and retraction device having a longitudinal axis is provided that includes an injection assembly, a retraction assembly, and a pre-filled syringe cartridge. The injection assembly has an activation-prevention feature moveable between an on position and an off position. The retraction assembly has a needle guard that is removable in a direction along the longitudinal axis upon application of a removal force. The pre-filled syringe cartridge has a hypodermic needle with a needle sheath thereon. The retraction and injection assemblies are secured to one another so that the pre-filled syringe cartridge is in the retraction assembly with the needle sheath secured to the needle guard. The retraction and injection assemblies are configured so that, upon application of a twisting torque to the injection and retraction assemblies, the activation-prevention feature moves from the on position to the off position simultaneous with applying the removal force to the needle guard.

Claims

1. An automatic injection and retraction device having a longitudinal axis, comprising:

an injection assembly having an activation-prevention feature moveable between an on position and an off position;

a retraction assembly having a needle guard, said needle guard being removable from said retraction assembly in a direction along the longitudinal axis upon application of a removal force; and

a pre-filled syringe cartridge having a hypodermic needle with a needle sheath thereon, said retraction assembly being secured to said injection assembly so that said pre-filled syringe cartridge is disposed in said retraction assembly with said needle sheath secured to said needle guard,

wherein said injection and retraction assemblies are configured so that, upon application of a twisting torque to said injection and retraction assemblies about the longitudinal axis, said activation-prevention feature is configured to move from said on position to said off position simultaneous with applying said removal force to said needle guard.

2. The automatic injection and retraction device as in claim 1, wherein said injection and retraction assemblies have cooperating cam surfaces configured to transmit said twisting torque as said removal force.

3. The automatic injection and retraction device as in claim 1, wherein said activation-prevention feature is configured to prevent movement from said off position to said on position.

4. The automatic injection and retraction device as in claim 1, wherein said retraction assembly, after use, is configured to permanently receive said needle guard having said needle sheath secured thereto so that said hypodermic needle is enclosed within said retraction assembly.

5. The automatic injection and retraction device as in claim 1, further comprising a temporary engagement feature between said injection assembly and a medicine compartment of said pre-filled syringe cartridge so that said injection assembly is configured to move said pre-filled syringe cartridge a predetermined distance along the longitudinal axis without said injection assembly drivingly engaging a piston of said pre-filled syringe cartridge.

6. The automatic injection and retraction device as in claim 5, wherein, after movement of said pre-filled syringe cartridge said predetermined distance, said temporary engagement feature is configured to release from said injection assembly so that said injection assembly is drivingly engaged to said piston of said pre-filled syringe cartridge.

7. An automatic injection and retraction device having a longitudinal axis, comprising:

an injection assembly having an activation sub-assembly and an injection sub-assembly, said activation sub-assembly being rotatable with respect said injection sub-assembly about the longitudinal axis but not moveable with respect to said injection sub-assembly along the longitudinal axis;

a retraction assembly having a retraction sub-assembly and a needle guard, said needle guard being moveable with respect said retraction sub-assembly along the longitudinal axis but not rotatable with respect to said retraction sub-assembly along the longitudinal axis; and

a pre-filled syringe cartridge having a hypodermic needle with a needle sheath thereon, said retraction assembly being secured to said injection assembly so that said pre-filled syringe cartridge is disposed in said retraction assembly with said needle sheath secured to said needle guard,

wherein said needle guard having said needle sheath secured thereto is removed from said retraction sub-assembly in a direction along the longitudinal axis upon application of a twisting torque to said activation sub-assembly and said needle guard about the longitudinal axis.

8. The automatic injection and retraction device as in claim 7, wherein said injection assembly further comprises an activation-prevention feature moveable between an on position and an off position.

9. The automatic injection and retraction device as in claim 8, wherein said activation-prevention feature is moved from said on position to said off position simultaneously with said needle guard and said needle sheath being moved in said direction upon application of said twisting torque.

10. The automatic injection and retraction device as in claim 8, wherein said activation-prevention feature is configured to prevent movement from said off position to said on position.

11. The automatic injection and retraction device as in claim 7, wherein said retraction sub-assembly, after use, is configured to permanently receive said needle guard having said needle sheath secured thereto so that said hypodermic needle is enclosed within said retraction assembly.

12. The automatic injection and retraction device as in claim 7, wherein said activation sub-assembly comprises an activation button and a cap, said activation button being received in said cap so that said activation button is moveable with respect said cap along the longitudinal axis but not rotatable with respect to said cap along the longitudinal axis.

13. The automatic injection and retraction device as in claim 7, wherein said pre-filled syringe cartridge further comprises a medicine compartment permanently affixed to and in fluid communication with said hypodermic needle and a piston slidably received in said medicine compartment.

14. The automatic injection and retraction device as in claim 13, wherein said injection sub-assembly comprises a housing component, a plunger rod, and a syringe ring, said housing component having a first bore and a second bore, said plunger being secured to said syringe ring when said syringe ring is received in said first bore so that said plunger rod drivingly engages said medicine compartment but not said piston, said plunger rod being free of said plunger rod when said syringe ring is received in said second bore so that said plunger rod drivingly engages said piston but not said medicine compartment.

15. The automatic injection and retraction device as in claim 7, wherein said retraction sub-assembly comprises one or more first linear members cooperate with a corresponding number of second linear members disposed on said needle guard so that said needle guard is moveable with respect said retraction sub-assembly along the longitudinal axis but not rotatable with respect to said retraction sub-assembly along the longitudinal axis.

16. The automatic injection and retraction device as in claim 7, wherein said needle guard comprises a sight opening defined therethrough and said retraction sub-assembly is made of substantially transparent material so that a user has a direct line of sight to said pre-filled syringe cartridge.

17. The automatic injection and retraction device as in claim 7, wherein said needle guard and said cap comprise cooperating cam surfaces so that said twisting torque is converted to a removal force acting on said needle guard.

18. A method of providing a parenteral injection of liquid medicament, comprising:

twisting an injection assembly with respect to a retraction assembly so that said injection assembly is simultaneously moved to an armed position and said retraction assembly is separated from a needle guard, said needle guard being engaged to a needle sheath so that separation of said needle guard from said retraction assembly removes said needle sheath from a hypodermic needle within said retraction assembly.

19. The method as in claim 18, further comprising activating said injection assembly so as to release an injection spring within said injection assembly so that said injection spring provides the parenteral injection through said hypodermic needle and energizes a retraction spring of said retraction assembly, wherein said retraction spring retracts said hypodermic needle into said retraction assembly after the parenteral injection.

20. The method as in claim 19, further comprising permanently resecuring said needle guard to said retraction assembly so that said needle sheath and said needle guard enclose said hypodermic needle within said retraction assembly.