Cerebral perfusion augmentation
First Claim
Patent Images
1. A method for increasing cerebral blood flow, comprising the steps of:
- advancing a catheter into the descending aorta, the catheter having a proximal region, a distal region, and an expandable member mounted on the distal region;
locating the expandable member in the aorta;
expanding and maintaining the expandable member to partially obstruct blood flow in the aorta during systole and diastole; and
measuring a physiologic parameter.
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Abstract
Methods are provided for partial aortic occlusion for cerebral perfusion augmentation in patients suffering from global or focal cerebral ischemia. The descending aorta is accessed. A device is then located downstream from the takeoff of the brachiocephalic artery. The device is operated to at least partially obstruct blood flow in the aorta during systole and diastole. A physiologic parameter can be measured. The device can then be adjusted to modify the degree of obstruction based on the measured physiologic parameter.
91 Citations
18 Claims
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1. A method for increasing cerebral blood flow, comprising the steps of:
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advancing a catheter into the descending aorta, the catheter having a proximal region, a distal region, and an expandable member mounted on the distal region; locating the expandable member in the aorta; expanding and maintaining the expandable member to partially obstruct blood flow in the aorta during systole and diastole; and measuring a physiologic parameter. - View Dependent Claims (3, 4, 6, 7)
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2. The method of claim I, further comprising the step of adjusting the expansion of the expandable member based on the measured physiologic parameter.
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5. The method of claim I, wherein the expandable member is a balloon.
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8. A method for increasing cerebral blood flow, comprising the steps of:
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advancing a catheter into the descending aorta, the catheter having a proximal region, a distal region, and an expandable member mounted on the distal region; locating the expandable member in the aorta; expanding the expandable member to partially obstruct blood flow in the aorta without full occlusion during systole and diastole; and measuring a physiologic parameter. - View Dependent Claims (9, 10, 11, 12, 13, 14)
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15. A method for increasing cerebral blood flow, comprising the steps of:
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advancing a catheter into the descending aorta, the catheter having a proximal region, a distal region, and a balloon mounted on the distal region; locating the balloon in the descending aorta; expanding and maintaining the balloon to partaily obstruct blood flow in the descending aorta during systole and diastole; and measuring a blood pressure. - View Dependent Claims (16, 17, 18)
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Specification