Compositions and methods for management of diabetes
First Claim
1. A method for providing an extract from buckwheat seed wherein the extract is effective for inhibiting systemic glucose uptake into an individual'"'"'s blood stream, said method comprising:
- contacting buckwheat seed with a first solvent to produce a first extract, said first solvent comprising a non-polar solvent;
contacting said buckwheat seed a second time with a second solvent to produce a second extract, said second solvent comprising a polar aprotic solvent;
contacting said buckwheat seed a third time with a third solvent to produce a third extract, said third solvent selected from the group comprising polar aprotic solvents and polar protic solvents; and
drying said third extract to remove the third solvent therefrom.
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Accused Products
Abstract
A buckwheat extract comprising at least myo-inositol, D-chiro-inositol, a fagopyritol, one MAPK-stimulating compound, and one glucose-uptake inhibiting compound. A substantially pure glucose-uptake inhibiting compound selected from a buckwheat extract. A method for providing a glucose-uptake inhibiting extract from buckwheat seed comprising first contacting said buckwheat seed with a non-polar solvent, then contacting said buckwheat seed with a polar aprotic solvent, and then finally contacting said buckwheat seed with a third solvent. The third solvent may be a polar aprotic solvent or a polar protic solvent. The extract produced by contacting buckwheat seed with the third solvent is dried to remove the solvent therefrom. Compositions comprising dried glucose-uptake inhibiting buckwheat extracts and purified compounds therefrom.
12 Citations
21 Claims
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1. A method for providing an extract from buckwheat seed wherein the extract is effective for inhibiting systemic glucose uptake into an individual'"'"'s blood stream, said method comprising:
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contacting buckwheat seed with a first solvent to produce a first extract, said first solvent comprising a non-polar solvent; contacting said buckwheat seed a second time with a second solvent to produce a second extract, said second solvent comprising a polar aprotic solvent; contacting said buckwheat seed a third time with a third solvent to produce a third extract, said third solvent selected from the group comprising polar aprotic solvents and polar protic solvents; and drying said third extract to remove the third solvent therefrom. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21)
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Specification