Far-field sensing channel for implantable cardiac device

• US 7,996,083 B2
• Filed: 06/02/2004
• Issued: 08/09/2011
• Est. Priority Date: 06/02/2004
• Status: Active Grant

• Current Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Original Assignee: Cardiac Pacemakers Incorporated (Boston Scientific Corporation)
• Inventors: Gilkerson, James O., Zhang, Geng, Ni, Quan, Daum, Douglas R.
• Primary Examiner(s): KAHELIN, MICHAEL WILLIAM
• Application Number:
  US10/858,848
• Publication Number:
  US 20050288719A1
• Time in Patent Office: 2,624 Days
• Field of Search: 600/508, 600/509, 607/5, 607/9
• US Class Current: 607/9
• CPC Class Codes: A61N 1/3621 for treating or preventing abnormally high heart rate
• CPC Class Codes: A61N 1/371 Capture, i.e. successful stimulation
• CPC Class Codes: A61N 1/3756 Casings with electrodes thereon, e.g. leadless stimulators

Abstract

An implantable pacemaker is provided with a far-field sensing channel which requires a reduced refractory period during the time when pacing pulses are delivered as compared with sensing channels using intra-cardiac electrodes. The far-field sensing channel may use the conductive housing of the implantable device or can and an indifferent electrode mounted on the device header as the electrodes for its differential inputs. Such a far-field sensing channel is able to sense activity occurring in either the atria or the ventricles for the purposes of arrhythmia detection and/or capture verification.

Claims

1. A device comprising:

an atrial sensing channel for incorporating one or more intracardiac electrodes adaptable for disposition near an atrium in order to generate an atrial electrogram;

a ventricular sensing channel for incorporating one or more intracardiac electrodes adaptable for disposition near a ventricle in order to generate a ventricular electrogram;

a pacing channel for incorporating one or more intracardiac electrodes adaptable for disposition near a ventricle or atrium and for delivering pacing pulses thereto;

a far-field sensing channel incorporating at least two far-field electrodes adaptable for disposition in order to generate a far-field electrogram that reflects activity in both the atria and ventricles;

a controller interfaced to the sensing channels and programmed with instructions for;

upon delivery of a pacing pulse, disabling the atrial and ventricular sensing channels for a blanking interval on the order of 15-20 ms and disabling the far-field sensing channel for a blanking interval on the order of 1-2 ms;

detecting a P-wave if two conditions are simultaneously met;

     1) the atrial electrogram exceeds a specified atrial channel threshold, and

     2) the far-field electrogram exceeds a specified far-field atrial threshold;

detecting an R-wave if two conditions are simultaneously met;

     1) the ventricular electrogram exceeds a specified ventricular channel threshold, and

     2) the far-field electrogram exceeds a specified far-field ventricular threshold;

wherein the far-field ventricular threshold is higher than the far-field atrial threshold; and

,

detecting an arrhythmia when the intervals between detected P-waves or between detected R-waves meets a specified rate criterion.

2. The device of claim 1 further comprising:

a minute ventilation sensor for measuring transthoracic impedance in order to generate a signal proportional to minute ventilation, the minute ventilation sensor including an exciter for supplying an oscillating excitation current between a pair of excitation current electrodes and a pair of voltage sense electrodes for generating an impedance signal; and

,

an indifferent electrode adapted for subcutaneous disposition;

wherein the indifferent electrode is both;

     1) incorporated into the far-field sensing channel and,

     2) utilized by the minute ventilation sensor as an excitation current electrode; and

,

wherein the controller is programmed such that the far-field sensing channel is made active only during periods when no excitation current is being supplied.

3. The device of claim 1 further comprising:

a minute ventilation sensor for measuring transthoracic impedance in order to generate a signal proportional to minute ventilation, the minute ventilation sensor including an exciter for supplying an oscillating excitation current between a pair of excitation current electrodes and a pair of voltage sense electrodes for generating an impedance signal;

an indifferent electrode adapted for subcutaneous disposition;

wherein the indifferent electrode is both;

     1) incorporated into the far-field sensing channel and,

     2) utilized by the minute ventilation sensor as a voltage sense electrode; and

,

wherein the controller is programmed such that the far-field sensing channel is made active only during periods when no excitation current is being supplied.

4. The device of claim 1 further comprising:

an implantable housing;

a header formed of insulating material mounted on the housing for receiving one or more sensing or pacing leads; and

,

an indifferent electrode mounted on the header that serves as a far-field electrode.

5. The device of claim 1 further comprising:

an implantable conductive housing that serves as a far-field electrode;

a header formed of insulating material mounted on the housing for receiving one or more sensing or pacing leads; and

,

an indifferent electrode mounted on the header that serves as a far-field electrode.

6. The device of claim 1 further comprising a subcutaneous electrode that serves as a far-field electrode.

7. The device of claim 1 further comprising:

an implantable conductive housing that serves as a far-field electrode; and

,

a subcutaneous electrode that serves as a far-field electrode.

8. The device of claim 1 further comprising atrial and ventricular pacing channels and wherein the controller is further programmed with instructions for verifying whether capture by either an atrial or ventricular pacing pulse has occurred by determining whether the far-field electrogram signal after an atrial or ventricular pace indicates an evoked response.

9. A method for operating a cardiac device, comprising:

generating an atrial electrogram in an atrial sensing channel incorporating an intracardiac electrode disposed near an atrium;

generating a ventricular electrogram in a ventricular sensing channel incorporating an intracardiac electrode disposed near a ventricle;

generating a far-field electrogram in a far-field sensing channel incorporating at least two far-field electrodes disposed in order for the far-field electrogram to reflect activity in both the atria and ventricles;

delivering pacing pulses to an atrium or a ventricle;

upon delivery of a pacing pulse, disabling the atrial and ventricular sensing channels for a blanking interval on the order of 15-20 ms and disabling the far-field sensing channel for a blanking interval on the order of 1-2 ms;

detecting a P-wave if two conditions are simultaneously met;

     1) the atrial electrogram exceeds a specified atrial channel threshold, and

     2) the far-field electrogram exceeds a specified far-field atrial threshold;

detecting an R-wave if two conditions are simultaneously met;

     1) the ventricular electrogram exceeds a specified ventricular channel threshold, and

     2) the far-field electrogram exceeds a specified far-field ventricular threshold;

wherein the far-field ventricular threshold is higher than the far-field atrial threshold; and

,

detecting an arrhythmia when the intervals between detected P-waves or between detected R-waves meets a specified rate criterion.

10. The method of claim 9 further comprising:

measuring transthoracic impedance with a minute ventilation sensor in order to generate a signal proportional to minute ventilation, the minute ventilation sensor including an exciter for supplying an oscillating excitation current between a pair of excitation current electrodes and a pair of voltage sense electrodes for generating an impedance signal;

utilizing a far-field electrode as an excitation current electrode for the minute ventilation sensor; and

,

activating the far-field channel only during periods when no excitation current is supplied.

11. The method of claim 9 further comprising:

measuring transthoracic impedance with a minute ventilation sensor in order to generate a signal proportional to minute ventilation, the minute ventilation sensor including an exciter for supplying an oscillating excitation current between a pair of excitation current electrodes and a pair of voltage sense electrodes for generating an impedance signal;

utilizing a far-field electrode as a voltage sense electrode for the minute ventilation sensor; and

,

activating the far-field channel only during periods when no excitation current is supplied.

12. The method of claim 9 wherein the far-field electrogram is generated using an indifferent electrode mounted on a header of an implantable housing as a far -field electrode.

13. The method of claim 9 wherein the far-field electrogram is generated using an implantable housing as a far-field electrode and an indifferent electrode mounted on a header of the implantable housing as a far-field electrode.

14. The method of claim 9 wherein the far-field electrogram is generated using a subcutaneous electrode as a far-field electrode.

15. The method of claim 9 wherein the far-field electrogram is generated using an implantable conductive housing as a far-field electrode and a subcutaneous electrode as a far-field electrode.

16. The method of claim 9 further comprising delivering atrial and ventricular pacing pulses and verifying whether capture by either an atrial or ventricular pacing pulse has occurred by determining whether the far-field electrogram signal after an atrial or ventricular pace indicates an evoked response.

17. A device comprising:

an atrial sensing amplifier for connecting to one or more intracardiac electrodes disposed near an atrium in order to form an atrial sensing channel and generate an atrial electrogram;

a ventricular sensing amplifier for connecting to one or more intracardiac electrodes disposed near a ventricle in order to form a ventricular sensing channel and generate a ventricular electrogram;

a far-field sensing amplifier for connecting to at least two far-field electrodes in order to form a far-field sensing channel where the far-field electrodes are disposed so as to generate a far-field electrogram that reflects activity in both the atria and ventricles;

a pulse generator for connecting to one or more intracardiac electrodes adaptable for disposition near a ventricle or atrium in order to form a pacing channel for delivery of pacing pulses;

a controller interfaced to the sensing channels and programmed with instructions for;

upon delivery of a pacing pulse, disabling the atrial and ventricular sensing channels for a blanking interval on the order of 15-20 ms and disabling the far-field sensing channel for a blanking interval on the order of 1-2 ms;

detecting a P-wave if two conditions are simultaneously met;

     1) the atrial electrogram exceeds a specified atrial channel threshold, and

     2) the far-field electrogram exceeds a specified far-field atrial threshold;

detecting an R-wave if two conditions are simultaneously met;

     1) the ventricular electrogram exceeds a specified ventricular channel threshold, and

     2) the far-field electrogram exceeds a specified far-field ventricular threshold;

wherein the far-field ventricular threshold is higher than the far-field atrial threshold; and

,

detecting an arrhythmia when the intervals between detected P-waves or between detected R-waves meets a specified rate criterion.