Method of making a plurality of calibration-adjusted sensors
First Claim
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1. A method of making a plurality of calibration-adjusted sensors for use in determining a concentration of a ketone body in a sample, the method comprising:
- (a) providing a plurality of pre-sensors, each pre-sensor comprising a working electrode, a counter electrode, and a sample chamber, wherein the sample chamber has at least part of the working electrode and the counter electrode arranged therein, wherein the plurality of pre-sensors include at least a first pre-sensor and a second pre-sensor;
(b) physically modifying the first pre-sensor to form a first sensor, the first sensor having a first physical characteristic defining a first slope and a first y-intercept;
(c) determining the first slope and the first y-intercept of the first sensor;
(d) comparing the first slope of the first sensor to a first desired slope and comparing the first and y-intercept of the first sensor to a first desired y-intercept; and
(e) physically modifying the second pre-sensor to form a second sensor having a second physical characteristic defining a second slope and a second y-intercept of the second sensor such that the second slope of the second sensor is substantially equal to the first desired slope and such that the second y-intercept of the second sensor is substantially equal to the first desired y-intercept.
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Abstract
Methods of making sensors, for determining the concentration of an analyte, such as glucose, in a biological fluid such as blood or serum, using techniques such as coulometry, amperometry, and potentiometry. The sensor includes a working electrode and a counter electrode, and may include an insertion monitoring trace to determine correct positioning of the sensor in a connector. The sensor is calibration-adjusted, eliminating the need for a user to enter a calibration code or for the meter to read a calibration code.
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Citations
14 Claims
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1. A method of making a plurality of calibration-adjusted sensors for use in determining a concentration of a ketone body in a sample, the method comprising:
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(a) providing a plurality of pre-sensors, each pre-sensor comprising a working electrode, a counter electrode, and a sample chamber, wherein the sample chamber has at least part of the working electrode and the counter electrode arranged therein, wherein the plurality of pre-sensors include at least a first pre-sensor and a second pre-sensor; (b) physically modifying the first pre-sensor to form a first sensor, the first sensor having a first physical characteristic defining a first slope and a first y-intercept; (c) determining the first slope and the first y-intercept of the first sensor; (d) comparing the first slope of the first sensor to a first desired slope and comparing the first and y-intercept of the first sensor to a first desired y-intercept; and (e) physically modifying the second pre-sensor to form a second sensor having a second physical characteristic defining a second slope and a second y-intercept of the second sensor such that the second slope of the second sensor is substantially equal to the first desired slope and such that the second y-intercept of the second sensor is substantially equal to the first desired y-intercept. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification