Blood test apparatus and blood test method

• US 7,998,087 B2
• Filed: 01/31/2007
• Issued: 08/16/2011
• Est. Priority Date: 01/31/2006
• Status: Expired due to Fees

• Current Assignee: Panasonic Healthcare Holdings Co., Ltd.
• Original Assignee: Panasonic Corporation (Panasonic Holdings Corporation)
• Inventors: Amano, Yoshinori, Fujiwara, Masaki
• Primary Examiner(s): Bullock; In Suk
• Assistant Examiner(s): Wecker; Jennifer
• Application Number:
  US12/162,627
• Publication Number:
  US 20090177117A1
• Time in Patent Office: 1,658 Days
• Field of Search: None
• US Class Current: 600/583
• CPC Class Codes: A61B 2562/0295 Strip shaped analyte sensors for apparatus classified in A61B5/145 or A61B5/157 disposable multilayered or laminated electrodes G01N27/307; details of handling chemical test elements G01N33/4875
• CPC Class Codes: A61B 5/14532 for measuring glucose, e.g. by tissue impedance measurement
• CPC Class Codes: A61B 5/14535 for measuring haematocrit
• CPC Class Codes: A61B 5/1486 using enzyme electrodes, e.g. with immobilised oxidase
• CPC Class Codes: A61B 5/150022 for capillary blood or interstitial fluid
• CPC Class Codes: A61B 5/150099 by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
• CPC Class Codes: A61B 5/150213 Venting means
• CPC Class Codes: A61B 5/150358 Strips for collecting blood, e.g. absorbent optical reagent test strips G01N21/8483; chemical reagent test strips G01N33/4875, G01N33/52
• CPC Class Codes: A61B 5/150412 Pointed piercing elements, e.g. needles, lancets for piercing the skin blade-like piercing elements A61B5/150442
• CPC Class Codes: A61B 5/150519 Details of construction of hub, i.e. element used to attach the single-ended needle to a piercing device or sampling device
• CPC Class Codes: A61B 5/150595 by snap-lock (i.e. based on axial displacement)
• CPC Class Codes: A61B 5/150641 comprising means to impede repositioning of protection sleeve from covering to uncovering position
• CPC Class Codes: A61B 5/150702 fully automatically removed, i.e. the removing does not require any action by the user
• CPC Class Codes: A61B 5/150755 Blood sample preparation for further analysis, e.g. by separating blood components or by mixing
• CPC Class Codes: A61B 5/15087 short range, e.g. between console and disposable using implanted devices A61B5/150877
• CPC Class Codes: A61B 5/150954 Means for the detection of operative contact with patient, e.g. by temperature sensitive sensor
• CPC Class Codes: A61B 5/15109 Fully automatically triggered, i.e. the triggering does not require a deliberate action by the user, e.g. by contact with the patient's skin
• CPC Class Codes: A61B 5/15113 Manually triggered, i.e. the triggering requires a deliberate action by the user such as pressing a drive button
• CPC Class Codes: A61B 5/15117 comprising biased elements, resilient elements or a spring, e.g. a helical spring, leaf spring, or elastic strap
• CPC Class Codes: A61B 5/1513 comprising linear sliding guides comprising tooth-shaped elements A61B5/15132
• CPC Class Codes: A61B 5/1519 : comprising driving means, e.g. a spring, for propelling the piercing unit
• CPC Class Codes: A61B 5/157 : Devices characterised by integrated means for measuring characteristics of blood

Abstract

A blood test apparatus negatively pressurizes a vicinity of a site to be punctured for collecting blood at an appropriate time without resorting to a special operation. More specifically, a blood test apparatus includes a housing having an opening; a puncturer; a first sensor that detects contact of a front face of the opening with a site to be punctured; a negative pressure generator that negatively pressurizes an inside of the opening; and a blood sensor that collects blood. The negative pressure generator starts when the first sensor detects the contact of the front face of the opening with the site to be punctured.

Claims

1. A blood test apparatus, comprising:

a housing with an opening part;

a puncturer that is provided inside the opening part;

a first sensor that detects contact between a part to be punctured and a front surface of the opening part;

a negative pressure generator that creates a negative pressure inside the opening part;

a blood sensor that samples blood flowing out from the part punctured with the puncturer after the negative pressure is created inside the opening part by the negative pressure generator; and

a measuring circuit that measures a signal obtained from the blood sensor to analyze components in the blood, wherein;

the blood sensor is positioned to project from the front surface of the opening part and is mounted for movement in and out of the housing through the opening part;

the first sensor is configured to detect that the blood sensor is forced into the opening part by the part to be punctured; and

the negative pressure generator starts when the first sensor detects that the blood sensor is forced into the opening part.

2. The blood test apparatus according to claim 1, wherein the negative pressure generator stops when the first sensor detects a non-contact between the part to be punctured and the front surface of the opening part.

3. The blood test apparatus according to claim 1, wherein the first sensor comprises a mechanical switch provided in the opening part that is pressed when the blood sensor is forced into the opening part by the part to be punctured.

4. The blood test apparatus according to claim 1, wherein the first sensor comprises an electrical switch or an optical switch provided in the opening part that detects an electrical change or an optical change caused when the blood sensor is forced into the opening part by the part to be punctured.

5. The blood test apparatus according to claim 1, further comprising a second sensor that detects a plumpness of the part to be punctured by the negative pressure.

6. The blood test apparatus according to claim 5, wherein the puncturer performs puncturing after the second sensor detects a plumpness of the part to be punctured.

7. The blood test apparatus according to claim 5, wherein the second sensor detects that the blood sensor is forced into the opening part by the plumped up part to be punctured.

8. The blood test apparatus according to claim 1, wherein:

the blood sensor comprises;

a storage into which blood flowing out from the part punctured with the puncturer is directed;

a supply channel, one end of the supply channel communicates with the storage, and into which the blood in the storage flows;

a detector which is provided in the supply channel, and in which an electrode system is provided; and

an air hole which communicates with an other end of the supply channel,

wherein the negative pressure generator creates a negative pressure in the supply channel via the air hole to facilitate an inflow of the blood in the storage to the supply channel.

9. The blood test apparatus according to claim 5, wherein:

the blood sensor comprises;

a storage into which blood flowing out from the part punctured with the puncturer is directed;

a supply channel, one end of the supply channel communicates with the storage, and into which the blood in the storage flows;

a detector which is provided in the supply channel, and in which an electrode system is provided; and

an air hole which communicates with an other end of the supply channel,

wherein the negative pressure generator creates a negative pressure in the supply channel via the air hole to facilitate an inflow of the blood in the storage to the supply channel.

10. The blood test apparatus according to claim 8, wherein the negative pressure generator stops when the electrode system detects an inflow of the blood to the supply channel.

11. The blood test apparatus according to claim 1, wherein the puncturer comprises:

a lancet, one end of which is held by a plunger that moves back and forth inside the housing; and

a blood collection needle attached to an other end of the lancet.

12. The blood test apparatus according to claim 1, wherein:

the blood sensor together with a holder that holds the blood sensor comprises an integrated blood sampling cartridge; and

the blood sampling cartridge is removably attached to the opening part.

13. The blood test apparatus according to claim 1, wherein:

the puncturer, the blood sensor and a holder comprise an integrated blood sampling cartridge;

the puncturer comprises;

a lancet, one end of which is held by a plunger that moves back and forth inside the housing; and

a blood collection needle attached to an other end of the lancet; and

the blood sampling cartridge is removably attached to the opening part.

14. The blood test apparatus according to claim 13, wherein the puncturer and the blood sensor in the blood sampling cartridge attached to the opening part are mounted for movement relative to each other.

15. The blood test apparatus according to claim 13, wherein the first sensor detects a move of the blood sensor of the blood sampling cartridge attached to the opening part, toward inside the opening part.

16. A method for examining blood with the blood test apparatus according to claim 1, comprising:

detecting contact between the part to be punctured and the front surface of the opening part, by the first sensor;

creating a negative pressure inside the opening part by the negative pressure generator;

puncturing the part to be punctured by the puncturer;

sampling blood flowing out from the punctured part in the blood sensor; and

analyzing components in the sampled blood.

17. The method according to claim 16, further comprising detecting a non-contact between the part of the skin to be punctured and the front surface of the opening part by the first sensor and stopping the negative pressure generator.

18. A method for examining blood with the blood test apparatus according to claim 8, comprising:

detecting contact between the part to be punctured and the front surface of the opening part, by the first sensor;

creating a negative pressure inside the opening part by the negative pressure generator;

puncturing the part to be punctured by the puncturer;

sampling blood flowing out from the punctured part in the blood sensor;

detecting an inflow of the blood to the blood supply channel by the electrode system and stopping the negative pressure generator; and

analyzing components in the sampled blood.

19. A method for examining blood with the blood test apparatus according to claim 9, comprising:

detecting contact between the part to be punctured and the front surface of the opening part, by the first sensor;

creating a negative pressure in the opening part by the negative pressure generator;

detecting a plumpness of the part to be punctured, by the second sensor;

puncturing the part to be punctured by the puncturer;

sampling blood flowing out from the punctured part in the blood sensor;

detecting an inflow of the blood to the blood supply channel by the electrode system and stopping the negative pressure generator; and

analyzing components in the sampled blood.