Antimicrobial material and method for making the same
First Claim
1. A method for producing an antimicrobial material comprising the steps of:
- (a) providing polyurethane (PU) to a solvent solution;
(b) providing polyethylene vinyl acetate (PEVA) to the solvent solution in a predetermined amount;
(c) providing a soluble ionic silver compound to the solvent solution in a predetermined amount; and
(d) forming a unitary predetermined shape using a one-stage melt process that combines the solution of steps (a), (b) and (c) all in one operation to output the unitary predetermined shape, and thereafter removing the solvent.
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Accused Products
Abstract
This invention provides a modified catheter biomaterial that provides both immediate, and long-term microbiocidal effects on otherwise antibiotic-resistant strains of microorganisms. The material, which exhibits good mechanical performance characteristics for medical devices, is composed of a hydrophobic polyurethane (PU), a hydrophilic polyethylene vinyl acetate (PEVA), a soluble silver salt and a sparsely-soluble silver salt. The hydrophobic polyurethane provides the good physical properties, the PEVA the hydrophilicity necessary to allow some water ingress into the catheter, the soluble silver salt for an immediate burst effect, and the sparsely-soluble silver salt for sustained-release over many months postimplantation.
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Citations
14 Claims
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1. A method for producing an antimicrobial material comprising the steps of:
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(a) providing polyurethane (PU) to a solvent solution; (b) providing polyethylene vinyl acetate (PEVA) to the solvent solution in a predetermined amount; (c) providing a soluble ionic silver compound to the solvent solution in a predetermined amount; and (d) forming a unitary predetermined shape using a one-stage melt process that combines the solution of steps (a), (b) and (c) all in one operation to output the unitary predetermined shape, and thereafter removing the solvent. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
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Specification