Deposition products, composite materials and processes for the production thereof

• US 7,998,504 B2
• Filed: 05/27/2008
• Issued: 08/16/2011
• Est. Priority Date: 05/16/2003
• Status: Active Grant

• Current Assignee: Argent Limited Partnership
• Original Assignee: Exciton Technologies Inc.
• Inventors: Djokic, Stojan
• Primary Examiner(s): Arnold; Ernst
• Application Number:
  US12/127,348
• Publication Number:
  US 20080233161A1
• Time in Patent Office: 1,176 Days
• Field of Search: None
• US Class Current: 424/445
• CPC Class Codes: A01N 2300/00 Combinations or mixtures of active ingredients covered by classes A01N27/00 - A01N65/48 with other active or formulation relevant ingredients, e.g. specific carrier materials or surfactants, covered by classes A01N25/00 - A01N65/48
• CPC Class Codes: A01N 25/34 Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
• CPC Class Codes: A01N 59/00 Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• CPC Class Codes: A01N 59/02 Sulfur; Selenium; Tellurium; Compounds thereof
• CPC Class Codes: A01N 59/16 Heavy metals; Compounds thereof
• CPC Class Codes: A61L 15/18 containing inorganic materials
• CPC Class Codes: A61L 15/46 Deodorants or malodour counteractants, e.g. to inhibit the formation of ammonia or bacteria
• CPC Class Codes: A61L 17/005 containing a biologically active substance, e.g. a medicament or a biocide
• CPC Class Codes: A61L 2300/104 Silver, e.g. silver sulfadiazine
• CPC Class Codes: A61L 2300/404 Biocides, antimicrobial agents, antiseptic agents
• CPC Class Codes: A61L 27/54 Biologically active materials, e.g. therapeutic substances A61L27/227 takes precedence
• CPC Class Codes: A61L 29/16 Biologically active materials, e.g. therapeutic substances A61L29/048 takes precedence
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence
• CPC Class Codes: B05D 1/18 performed by dipping
• CPC Class Codes: B05D 5/00 Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures
• CPC Class Codes: B05D 7/02 to macromolecular substances, e.g. rubber treatment or coating of shaped articles made of macromolecular substances C08J7/00
• CPC Class Codes: C23C 18/1646 Characteristics of the product obtained
• CPC Class Codes: C23C 18/42 Coating with noble metals
• CPC Class Codes: Y10T 428/256 Heavy metal or aluminum or compound thereof
• CPC Class Codes: Y10T 428/2949 Glass, ceramic or metal oxide in coating

Abstract

A composite material comprising a substrate and a deposition product and the use of a deposition product for providing an antimicrobial effect. The substrate of the composite material is a medical device. Further, in each of the composite material and the use, the deposition product consists essentially of at least one oxidized silver species and wherein the deposition product is comprised of a compound having the formula Ag₇O₈X, where X is an anion.

Claims

1. A composite material comprising a substrate and a deposition product, wherein the substrate is a medical device selected from a group of medical devices consisting of a wound dressing, a splint, a suture, a catheter, an implant, a tracheal tube, a drain, a shunt, a needle and an adhesive, and wherein the deposition product consists essentially of at least one oxidized silver species, and wherein the deposition product is comprised of a compound having the formula Ag₇O₈X, where X s an anion.

2. The composite material as claimed in claim 1 wherein the deposition product is further comprised of Ag₂SO₄.

3. The composite material as claimed in claim 1 wherein the deposition product is further comprised of at least one silver oxide selected from the group of silver oxides consisting of monovalent silver oxide, bivalent silver oxide, trivalent silver oxide and mixtures thereof.

4. The composite material as claimed in claim 1 wherein X is derived from an acid.

5. The composite material as claimed in claim 1 wherein the deposition product is comprised of a plurality of oxidized silver species having a plurality of valent states of silver.

6. The composite material as claimed in claim 1 wherein X is selected from the group of anions consisting of HCO₃⁻

, CO₃²⁻

, NO₃⁻

, ClO₄⁻

, SO₄²⁻

, F⁻

, and mixtures thereof.

7. The composite material as claimed in claim 6 wherein X is comprised of NO₃⁻

.

8. The composite material as claimed in claim 1 wherein the medical device is a wound dressing.

9. The composite material as claimed in claim 8 wherein the wound dressing is comprised of a high density polyethylene material.

10. The composite material as claimed, in claim 8 wherein the wound dressing is comprised of a cross-linked silicon gel.

11. The composite material as claimed in claim 8 wherein the wound dressing is comprised of a skin adhesive layer, wherein the skin adhesive layer is comprised of a cross-linked silicon gel, and wherein the deposition product is deposited on the skin adhesive layer.

12. The composite material as claimed in claim 11 wherein the deposition product is further comprised of Ag₂SO₄.

13. The composite material as claimed in claim 11 wherein the deposition product is further comprised of at least one silver oxide selected from the group of silver oxides consisting of monovalent silver oxide, bivalent silver oxide, trivalent silver oxide and mixtures thereof.

14. The composite material as claimed in claim 11 wherein X is derived from an acid.

15. The composite material as claimed in claim 11 wherein the deposition product is comprised of a plurality of oxidized silver species having a plurality of valent states of silver.

16. The composite material as claimed in claim 11 wherein X is selected from the group of anions consisting of HCO₃⁻

, CO₃²⁻

, NO₃⁻

, ClO₄⁻

, SO₄²⁻

, F⁻

, and mixtures thereof.

17. The composite material as claimed in claim 16 wherein X is comprised of NO₃⁻

.

18. The composite material as claimed in claim 11 wherein the skin adhesive layer has adhesive properties and wherein the deposition product does not materially interfere with the adhesive properties of the skin adhesive layer.