Integrated devices having extruded electrode structures and methods of using same
First Claim
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1. An integrated medication delivery device and electrode structure, comprising:
- an electrode structure comprisinga first conductive material, a second conductive material, and a dielectric material,wherein the first conductive material, the second conductive material, and the dielectric material are coextruded to provide an electrode structure having the first conductive material and the second conductive material electrically isolated by the dielectric material,wherein the first conductive material comprises a working electrode and the second conductive material comprises a reference/counter electrode, the working electrode comprising an analyte responsive enzyme disposed on, in or proximate thereto,wherein the electrode structure comprises a lumen, the lumen comprising a first opening, a second opening, and a lumen wall,wherein the dielectric material defines the lumen wall, andwherein the electrode structure includes a plurality of stand-offs along the lumen wall and extending inward into the lumen; and
a medication delivery device coupled to the lumen and configured to deliver a medication through the lumen to the subject.
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Abstract
The present disclosure provides electrode structures and integrated electrode structures having one or more conductive materials coextruded with one or more dielectric materials. The disclosed electrode structures can be configured for use as analyte sensors. Also provided, are methods of making and using the electrode structures and integrated electrode structures described herein.
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Citations
20 Claims
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1. An integrated medication delivery device and electrode structure, comprising:
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an electrode structure comprising a first conductive material, a second conductive material, and a dielectric material, wherein the first conductive material, the second conductive material, and the dielectric material are coextruded to provide an electrode structure having the first conductive material and the second conductive material electrically isolated by the dielectric material, wherein the first conductive material comprises a working electrode and the second conductive material comprises a reference/counter electrode, the working electrode comprising an analyte responsive enzyme disposed on, in or proximate thereto, wherein the electrode structure comprises a lumen, the lumen comprising a first opening, a second opening, and a lumen wall, wherein the dielectric material defines the lumen wall, and wherein the electrode structure includes a plurality of stand-offs along the lumen wall and extending inward into the lumen; and a medication delivery device coupled to the lumen and configured to deliver a medication through the lumen to the subject. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18)
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19. An electrode structure for integration with a medication delivery device, comprising:
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a first conductive material; an enzyme coupled to the first conductive material; a second conductive material; a dielectric material, wherein the first conductive material, the second conductive material, and the dielectric material are coextruded to create a hollow lumen with a first opening, a second opening, and a lumen wall, and wherein the first conductive material and the second conductive material are electrically isolated by the dielectric material; and a plurality of stand-offs along the lumen wall and extending inward into the lumen.
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20. An electrode structure for integration with a medication delivery device, comprising:
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a first conductive material; an enzyme coupled to the first conductive material; a second conductive material; a dielectric material, wherein the first conductive material, the second conductive material, and the dielectric material are coextruded to create a hollow lumen with a first opening, a second opening, and a lumen wall, and wherein the first conductive material and the second conductive material are electrically isolated by the dielectric material; and a plurality of stand-offs along the lumen wall and extending inward into the lumen, wherein each stand-off is positioned such that the stand-off does not contact the second conductive material.
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Specification