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Systems and methods for controlling position of charged polymer inside nanopore

  • US 8,003,319 B2
  • Filed: 02/02/2007
  • Issued: 08/23/2011
  • Est. Priority Date: 02/02/2007
  • Status: Active Grant
First Claim
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1. A method for controlling a position of a linear charged polymer inside a nanopore, comprising the steps of:

  • using electrostatic control to position a linear charged polymer inside a nanopore; and

    applying an independent voltage to each of three locking electrodes, wherein the three locking electrodes each have a cylindrical geometry and are separated by one or more insulators, creating an electrostatic potential well inside the nanopore that varies along nanopore via setting an electrical potential of each of the three locking electrodes independently, wherein the electrical potential of a second locking electrode differs from the electrical potential of a first and third locking electrode, andwherein the electrostatic potential well controls a position of the linear charged polymer inside the nanopore, wherein controlling a position of the linear charged polymer inside the nanopore comprises using the electrostatic potential well to lock the position of one monomer of the linear charged polymer inside the nanopore.

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