Method and system for automatic quantification of aortic valve function from 4D computed tomography data using a physiological model
First Claim
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1. A method for generating a dynamic aortic valve model, comprising:
- receiving a 4D cardiac image sequence comprising a plurality of frames, each frame comprising 3D image data;
determining an initial estimate for a physiological aortic valve model in at least one reference frame of the plurality of frames based on anatomical landmarks in the at least one reference frame;
refining the initial estimate for the physiological aortic valve model in the at least one reference frame using boundary detection to generate a final estimate for the physiological aortic valve model in the at least one reference frame; and
generating a dynamic aortic valve model by estimating the physiological aortic valve model for remaining frames of the plurality of frames based on the final estimate for the physiological aortic valve model in the at least one reference frame.
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Abstract
A method and system for modeling the aortic valve in 4D image data, such as 4D CT and echocardiography, is disclosed. An initial estimate of a physiological aortic valve model is determined for at least one reference frame of a 4D image sequence based on anatomic features in the reference frame. The initial estimate is refined to generate a final estimate in the reference frame. A dynamic model of the aortic valve is then generated by estimating the physiological aortic valve model for each remaining frame of the 4D image sequence based on the final estimate in the reference frame. The aortic valve can be quantitatively evaluated using the dynamic model.
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Citations
31 Claims
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1. A method for generating a dynamic aortic valve model, comprising:
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receiving a 4D cardiac image sequence comprising a plurality of frames, each frame comprising 3D image data; determining an initial estimate for a physiological aortic valve model in at least one reference frame of the plurality of frames based on anatomical landmarks in the at least one reference frame; refining the initial estimate for the physiological aortic valve model in the at least one reference frame using boundary detection to generate a final estimate for the physiological aortic valve model in the at least one reference frame; and generating a dynamic aortic valve model by estimating the physiological aortic valve model for remaining frames of the plurality of frames based on the final estimate for the physiological aortic valve model in the at least one reference frame. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15)
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16. An apparatus for generating a dynamic aortic valve model, comprising:
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means for receiving a 4D cardiac image sequence comprising a plurality of frames, each frame comprising 3D image data; means for determining an initial estimate for a physiological aortic valve model in at least one reference frame of the plurality of frames based on anatomical landmarks in the at least one reference frame; means for refining the initial estimate for the physiological aortic valve model in the at least one reference frame using boundary detection to generate a final estimate for the physiological aortic valve model in the at least one reference frame; and means for generating a dynamic aortic valve model by estimating the physiological aortic valve model for remaining frames of the plurality of frames based on the final estimate for the physiological aortic valve model in the at least one reference frame. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23)
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24. A computer readable medium encoded with computer executable instructions for generating a dynamic aortic valve model, the computer executable instructions defining steps comprising:
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receiving a 4D cardiac image sequence comprising a plurality of frames, each frame comprising 3D image data; determining an initial estimate for a physiological aortic valve model in at least one reference frame of the plurality of frames based on anatomical landmarks in the at least one reference frame; refining the initial estimate for the physiological aortic valve model in the at least one reference frame using boundary detection to generate a final estimate for the physiological aortic valve model in the at least one reference frame; and generating a dynamic aortic valve model by estimating the physiological aortic valve model for remaining frames of the plurality of frames based on the final estimate for the physiological aortic valve model in the at least one reference frame. - View Dependent Claims (25, 26, 27, 28, 29, 30, 31)
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Specification