Quick cycle biopsy system

• US 8,012,102 B2
• Filed: 03/01/2007
• Issued: 09/06/2011
• Est. Priority Date: 01/31/2005
• Status: Expired due to Fees

• Current Assignee: C.R. Bard, Inc. (Becton, Dickinson & Co)
• Original Assignee: C.R. Bard, Inc. (Becton, Dickinson & Co)
• Inventors: Kalis, Robert W., McCullough, Adam B.
• Primary Examiner(s): Hoekstra; Jeffrey G
• Application Number:
  US11/680,965
• Publication Number:
  US 20070149895A1
• Time in Patent Office: 1,650 Days
• Field of Search: 600/566, 600/562, 600/564, 600/567, 600/570, 600/571, 606/167, 606/174
• US Class Current: 600/566
• CPC Class Codes: A61B 10/0275 with sample notch, e.g. on the side of inner stylet
• CPC Class Codes: A61B 10/0283 with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe A61B10/025, A61B10/0266 take precedence
• CPC Class Codes: A61B 2010/0208 Biopsy devices with actuators, e.g. with triggered spring mechanisms
• CPC Class Codes: A61B 2010/0225 for taking multiple samples

Abstract

A method for extracting a tissue sample includes altering the pressure inside the lumen of a cannula to facilitate extraction of a tissue sample from the cannula. One aspect of the invention includes a biopsy apparatus comprising a valve for controlling the pressure inside the lumen of the cannula. In one variation, the pressure/vacuum generating device is connected to a cannula with a closed distal end and an orifice located on a circumferential surface of said cannula. A cutting sheath is slidably disposed over said cannula. The valve may be provided between the pressure/vacuum generating device and the cannula to control the pressure within the lumen of the cannula.

Claims

1. A biopsy device, comprising:

a biopsy cannula having a longitudinal axis, a lumen with a lumen wall, distal and proximal ends, and a sample chamber at the distal end of the biopsy cannula;

an access opening located at a circumferential surface of the biopsy cannula providing access to the sample chamber, the access opening facing radially away from the longitudinal axis and the sample chamber having a blind end opposite the access opening formed by a portion of the lumen wall of the biopsy cannula to define a bottom of the sample chamber;

a narrowing device positioned in the lumen of the biopsy cannula at a proximal end of the sample chamber to define a restriction in the lumen and an open area in the lumen, wherein a cross section of the open area between the narrowing device and the biopsy cannula at the restriction is less than 50 percent but greater than zero percent of a cross section of the lumen of the biopsy cannula, the open area being located to communicate with the sample chamber, the open area being positioned proximal to the access opening and at an opposite side of the lumen relative to the access opening at the blind end of the sample chamber;

a retractable sheath disposed to be movable relative to the sample opening; and

a vacuum source coupled in fluid communication with the lumen of the biopsy cannula for selectively supplying vacuum to the sample chamber via the open area at the restriction such that vacuum when applied will be brought to bear from the bottom of the sample chamber.

2. The device of claim 1, further comprising a controller configured to drive an operating sequence in which air is pumped into the sample chamber, the sample chamber is then uncovered by the covering sheath to cause air to expel a sample therein.

3. The device of claim 1, wherein the narrowing device defines a wall portion at the proximal end of the sample chamber to which a tissue sample will cling when vacuum is applied to the lumen during a cutting process, and wherein a cross section of the lumen of the biopsy cannula is closed between approximately 50 percent and 75 percent by the narrowing device, and the opening is formed as a single aperture.

4. The device of claim 1, further comprising a controller configured to drive an operating sequence in which air is pumped into the sample chamber, the sample chamber is then uncovered by the covering sheath to cause air to expel a sample therein.

5. The device of claim 1, wherein the retractable sheath includes a cutting sheath that is axially movable relative to the biopsy cannula and surrounds the biopsy cannula, the cutting sheath having a distal cutting surface.

6. The device of claim 1, further comprising a controller configured to drive an operating sequence in which air is pumped into the sample chamber, the sample chamber is then uncovered by the covering sheath to cause air to expel a sample therein.

7. The device of claim 1, wherein the sheath includes a cutting sheath that is axially movable relative to the stylet and surrounds the stylet, the cutting sheath having a distal cutting edge;

a drive configured to simultaneously rotate the cutting sheath while translating it from a proximal position, where the cutting edge is on a proximal end of the sample chamber access opening, toward the distal end, such that the cutting sheath covers the sample chamber access.

8. The biopsy device of claim 1, wherein the sample chamber is open above the portion of the lumen wall for approximately 25 percent of the cross section of the lumen of the biopsy cannula to form the access opening.

9. A biopsy device, comprising:

a biopsy cannula having a longitudinal axis, a lumen with a lumen wall, distal and proximal ends, and a sample chamber at the distal end of the biopsy cannula;

an access opening located at a circumferential surface of the biopsy cannula providing access to the sample chamber, the access opening facing radially away from the longitudinal axis and the sample chamber having a blind end opposite the access opening formed by a portion of the lumen wall of the biopsy cannula to define a bottom of the sample chamber;

a narrowing device located at a proximal end of the sample chamber to define a transition between the lumen and the sample chamber along the longitudinal axis, and an open area that bypasses the narrowing device to provide a fluid passage between the sample chamber and the lumen, the open area being positioned proximal to the access opening and at an opposite side of the longitudinal axis relative to the access opening such that the open area is adjacent the bottom of the sample chamber;

a retractable sheath that is selectively movable relative to the access opening; and

a vacuum source coupled in fluid communication with the lumen of the biopsy cannula.

10. The device of claim 9, further comprising a controller configured to drive an operating sequence in which air is pumped into the sample chamber, the sample chamber is then uncovered by the covering sheath to cause air to expel a sample therein.

11. The device of claim 9, wherein a cross section of the open area is less than 50 percent but greater than zero percent of a cross section of the lumen of the biopsy device, the open area being a single aperture.

12. The device of claim 11, further comprising a controller configured to drive an operating sequence in which air is pumped into the sample chamber, the sample chamber is then uncovered by the covering sheath to cause air to expel a sample therein.

13. The device of claim 9, wherein the retractable sheath includes a cutting sheath that is axially movable relative to the biopsy cannula and surrounds the biopsy cannula, the cutting sheath having a distal cutting surface.

14. The device of claim 13, further comprising a controller configured to drive an operating sequence in which air is pumped into the sample chamber, the sample chamber is then uncovered by the covering sheath to cause air to expel a sample therein.

15. The device of claim 9, wherein the sheath includes a cutting sheath that is axially movable relative to the stylet and surrounds the stylet, the cutting sheath having a distal cutting edge;

a drive configured to simultaneously rotate the cutting sheath while translating it from a proximal position where the cutting edge is on a proximal end of the sample chamber access opening toward the distal end such that it covers the sample chamber access.

16. The biopsy device of claim 9, wherein the sample chamber is open above the portion of the lumen wall for approximately 25 percent of the cross section of the lumen of the biopsy cannula to form the access opening.