Cartilage repair and regeneration device
First Claim
1. A cartilage repair device comprisinga plug configured to be positioned in an opening formed in damaged hyaline cartilage, the plug being formed from an extracellular matrix selected from the group consisting of vertebrate small intestine submucosa, vertebrate liver basement membrane, vertebrate bladder submucosa, vertebrate stomach submucosa, vertebrate alimentary tissue, vertebrate respiratory tissue, and vertebrate genital tissue,an exogenous biological lubricant applied to the extracellular matrix, wherein the biological lubricant is crosslinked onto the extracellular matrix, andan anchor secured to the plug, the anchor including a head, an elongated central body extending from the head, and at least one barb extending from the elongated central body for engagement with bone,wherein the extracellular matrix possesses sufficient compressive strength and sufficient shear strength to withstand the loads applied to hyaline cartilage when the plug is positioned in the opening formed in damaged hyaline cartilage.
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Abstract
A cartilage repair device comprises a scaffold, for example a naturally occurring extracellular matrix material, and a biological lubricant. The biological lubricant is applied to the naturally occurring extracellular matrix material.
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Citations
1 Claim
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1. A cartilage repair device comprising
a plug configured to be positioned in an opening formed in damaged hyaline cartilage, the plug being formed from an extracellular matrix selected from the group consisting of vertebrate small intestine submucosa, vertebrate liver basement membrane, vertebrate bladder submucosa, vertebrate stomach submucosa, vertebrate alimentary tissue, vertebrate respiratory tissue, and vertebrate genital tissue, an exogenous biological lubricant applied to the extracellular matrix, wherein the biological lubricant is crosslinked onto the extracellular matrix, and an anchor secured to the plug, the anchor including a head, an elongated central body extending from the head, and at least one barb extending from the elongated central body for engagement with bone, wherein the extracellular matrix possesses sufficient compressive strength and sufficient shear strength to withstand the loads applied to hyaline cartilage when the plug is positioned in the opening formed in damaged hyaline cartilage.
Specification